On the formation of the myotomes in avian embryos. An experimental and scanning electron microscope study

Summary The formation of the myotomes to chick embryos was studied by using experimental and scanning electron microscope techniques. With the aid of the quail-chick marker system, it was demonstrated that the dermatome gives rise to the myotome plate. SEM studies support the conclusion that the myotome cells originate only from the edges of the dermatome.Supported by the Deutsche Forschungsgemeinschaft (Ch 44/2).     

Dissolution of gallstones in hamsters by 3-hydroxy-3-methylglutaric acid

Summary Addition of 0.05–0.20% of 3-hydroxy-3-methylglutaric acid to a lithogenic hamster diet resulted in a marked reduction in the incidence of gallstones in hamsters.Supported, in part, by grants HL-03299, AG-00076 and T32 CA-09171 and a Research Career Award, HL-0734 from the National Institutes of Health.     

Respiratory function of blood and relative weight of certain organs in two species of shrew: Crocidura russula and Suncus etruscus (Soricidae mammals)]

A high oxygen capacity combined with a low oxygen affinity and a large Bohr effect achieve a high oxygen transport capacity in small shrews. The high metabolic rate (Suncus estruscus: 100 to 350 ml O2/kg. min) can be explained by the combination of the favorable blood parameters with a high relative heart weight (1,2% of body weight) and heart frequencies of 1,000 to 1,350 per minute.     

Immunocytology of alpha-endorphin positive hypothalamic fibers of Carassius auratus L. and Cyprinus carpio L.]

An immunocytological study of the basal hypothalamus of Carassius auratus and Cyprinus carpio with an alpha-endorphin antiserum shows the different nerve processes belonging probably to the immunoreactive cells of the lateral part of the N.L.T. According to their pathways, two main fibre tracts have been distinguished: many fluorescent fibres converge towards the pituitary gland into which they enter, other fibres run caudally through the tuber towards the nucleus tuberis inferior (Baumgarten and Braak) where they could not be followed further.     

Interaction of cocaine and bunaphtide on the3H-norepinephrine uptake mechanism on isolated left atrium of guinea-pig

Summary Bunaphtide induces a blockade in the³H-norepinephrine uptake and retention in the isolated guinea-pig left atrium. However, this blockade does not seems to be related with the cardiodepressant effect of the drug.     

Elevated glucose levels influence in vitro hatching,attachment, trophoblast outgrowth and differentiation of the mouse blastocyst

Summary A glucose concentration of 3.5 mg/ml is optimal for in vitro embryo attachment and trophoblastic cell outgrowth. Raising the concentration above 3.5 mg/ml does not improve embryo culture and can at certain concentrations be detrimental to embryo development.     

Variations au cours de la journée de l'incorporation in vivo de la leucine tritiée dans les protéines du cervelet et du cerveau du jeune rat normal et hypothyroïdien

Summary In the normal and hypothyroid 6-day-old rat, the specific radioactivity (RSA) and the relative RSA (ratio of the RSA to the [³H] leucine concentration of the acido soluble phase) of the cerebral and cerebellar proteins, change during the day synchronally. They show a maximum at 15.00 h and a minimum at 03.00 h. At all stages studied, these values are significantly lower in the hypothyroid animals than in normal ones.     

Effect of water oxygenation on oxygen consumption and gill ventilation of the crab, Carcinus maenas (L.)]

At 15 degrees C, the oxygen uptake rate of Carcinus maenas was practically independent of the ambient oxygen pressure betueen 50 and 500 Torr. Within this range, hyperventilatory and hypoventilatory responses were observed in hypoxic and hyperoxic conditions respectively whereas the oxygen extraction coefficient remained more or less constant.     

Electron microscope observation of "thyroidectomy cells" in the hypophyseal ventral lobe of a Chondrichthyan fish, the small spotted dogfish, Scyllium canicula Cuv.]

In the adenohypophysis of very young spotted dogfish, only one kind of granulated cells show strcutural changes following thyroidectomy: the small granule cells of the ventral lobe (granule diameter about 110 nm). These cells are similar to the thyrotrophs of other Vertebrates, and well distinct from the supposed gonadotrophs found in the same lobe.     

Nickel content of human lymphoblastoid cells cultured in a nickel sulfate-enriched medium]

Nickel is titrated by atomic absorption in nuclear and non-nuclear fractions of cells cultured in media supplemented by nickel sulphate. The living cell percentages are estimated in the same culture conditions. We try to connect the nickel presence in cellular fractions and the living cell percentages. These used cells seem to have mortality probability when nuclear fraction has 55 x 10(-6) of nickel and non-nuclear fraction has 33 x 10(-6) of nickel. We discuss the nickel stimulating effect for the start of DNA synthesis and the nickel penetration into cells.