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We analyse the nonlinear behaviour of the information content in the spread for future real economic activity. The spread linearly predicts one‐year‐ahead real growth in nine industrial production sectors of the USA and four of the UK over the last 40 years. However, recent investigations on the spread–real activity relation have questioned both its linear nature and its time‐invariant framework. Our in‐sample empirical evidence suggests that the spread–real activity relationship exhibits asymmetries that allow for different predictive power of the spread when past spread values were above or below some threshold value. We then measure the out‐of‐sample forecast performance of the nonlinear model using predictive accuracy tests. The results show that significant improvement in forecasting accuracy, at least for one‐step‐ahead forecasts, can be obtained over the linear model. Copyright © 2004 John Wiley & Sons, Ltd. 相似文献
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The effects of fire on nonbreeding songbird species in riparian habitat have not been studied. We compared body condition, within-year site fidelity, and between-year site fidelity of 3 songbird species ( Passerella iliaca , Fox Sparrow; Catharus guttatus , Hermit Thrush; and Regulus calendula , Ruby-crowned Kinglet) at 2 coastal riparian sites. Wildfire, which is rare in this habitat, had occurred at 1 of the sites before data collection. A significantly larger proportion of Passerella iliaca was recaptured in subsequent winters at the unburned site than at the burned site, but little difference was found between sites for Catharus guttatus or Regulus calendula . Body mass of all 3 species declined during winter at the burned site, but differences between sites were not significant. Similarly, body mass indices of new captures were lower at the burned site than the unburned site for all 3 species, but these differences were not significant. The within-year recapture rate for all 3 species combined declined at the burned site over the course of the study, possibly due to changes in vegetation structure caused by the fire. Overall, our data suggest that wintering songbirds were resilient to this disturbance, but that response to the post-fire environment differed among foraging guilds. Well-replicated studies that include pre-burn data are needed to evaluate the effects of this disturbance in riparian systems. 相似文献
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Reactive aldehydes are common carcinogens. They are also by-products of several metabolic pathways and, without enzymatic catabolism, may accumulate and cause DNA damage. Ethanol, which is metabolised to acetaldehyde, is both carcinogenic and teratogenic in humans. Here we find that the Fanconi anaemia DNA repair pathway counteracts acetaldehyde-induced genotoxicity in mice. Our results show that the acetaldehyde-catabolising enzyme Aldh2 is essential for the development of Fancd2(-/-) embryos. Nevertheless, acetaldehyde-catabolism-competent mothers (Aldh2(+/-)) can support the development of double-mutant (Aldh2(-/-)Fancd2(-/-)) mice. However, these embryos are unusually sensitive to ethanol exposure in utero, and ethanol consumption by postnatal double-deficient mice rapidly precipitates bone marrow failure. Lastly, Aldh2(-/-)Fancd2(-/-) mice spontaneously develop acute leukaemia. Acetaldehyde-mediated DNA damage may critically contribute to the genesis of fetal alcohol syndrome in fetuses, as well as to abnormal development, haematopoietic failure and cancer predisposition in Fanconi anaemia patients. 相似文献
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Genome-wide analysis reveals novel molecular features of mouse recombination hotspots 总被引:1,自引:0,他引:1
Smagulova F Gregoretti IV Brick K Khil P Camerini-Otero RD Petukhova GV 《Nature》2011,472(7343):375-378
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This research develops a methodology that helps actors in understanding information generated from multiple construction participants. It employs semiotic theory which approaches the interpreter’s understanding of the role of the representations used in construction documents to communicate meanings to other participants. This strategy is designed to aid the interpreters’ comprehension of the use of symbols. The symbols within the construction documents are forms of representations that take the form of a visual representation of a set of markers that describe a formal language, and of markers that are used to represent natural language as well as other possible representations, such as a collection of codes for indexing documents. Symbols are replaced by signs under the semiotics theory. The use of symbols as signs is this study’s recognition of the relationship between the interpreter and the material quality of symbols. The semiotic analysis is an examination of the compromise between the meanings of a representation per se and the concept associated with the understanding of such representation. 相似文献
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