全文获取类型
收费全文 | 47642篇 |
免费 | 254篇 |
国内免费 | 541篇 |
专业分类
系统科学 | 1219篇 |
丛书文集 | 93篇 |
教育与普及 | 277篇 |
理论与方法论 | 510篇 |
现状及发展 | 29895篇 |
研究方法 | 284篇 |
综合类 | 13972篇 |
自然研究 | 2187篇 |
出版年
2013年 | 803篇 |
2012年 | 494篇 |
2011年 | 2475篇 |
2009年 | 603篇 |
2008年 | 653篇 |
2007年 | 735篇 |
2006年 | 827篇 |
2005年 | 997篇 |
2004年 | 2137篇 |
2003年 | 1728篇 |
2002年 | 1393篇 |
2001年 | 1063篇 |
2000年 | 561篇 |
1999年 | 780篇 |
1998年 | 641篇 |
1997年 | 772篇 |
1996年 | 531篇 |
1995年 | 394篇 |
1994年 | 681篇 |
1993年 | 687篇 |
1992年 | 739篇 |
1991年 | 636篇 |
1990年 | 697篇 |
1989年 | 523篇 |
1988年 | 499篇 |
1987年 | 501篇 |
1986年 | 578篇 |
1985年 | 711篇 |
1984年 | 670篇 |
1983年 | 572篇 |
1982年 | 727篇 |
1981年 | 772篇 |
1980年 | 846篇 |
1979年 | 1155篇 |
1978年 | 1090篇 |
1977年 | 1072篇 |
1976年 | 981篇 |
1975年 | 945篇 |
1974年 | 719篇 |
1973年 | 1013篇 |
1972年 | 1089篇 |
1971年 | 1055篇 |
1970年 | 1061篇 |
1969年 | 1001篇 |
1968年 | 969篇 |
1967年 | 823篇 |
1966年 | 694篇 |
1965年 | 586篇 |
1964年 | 468篇 |
1963年 | 414篇 |
排序方式: 共有10000条查询结果,搜索用时 17 毫秒
971.
基于傅里叶变换近红外光谱技术,通过主成分分析(PCA),可较好地区分不同品牌的榨菜酱油样本.利用偏最小二乘法(PLS)建立了测定榨菜酱油成分的定量分析模型,校正集样本中总酸、氨基酸态氮和食盐的分析模型决定系数(R2)分别为98.44,98.74和98.48,交叉验证均方差(RMSECV)分别为0.001 3,0.008 44和0.355.预测集样本中总酸、氨基酸态氮和食盐的外部验证决定系数(R2)分别为96.04,95.90,96.27,预测集标准偏差(RMSEP)分别为0.017 4,0.012 9,0.48.实验结果具有较高的预测精度,可以用于测定榨菜酱油主要成分的质量浓度. 相似文献
972.
973.
应用2008年分布在茅台酒原料基地,海拔370~1 301m地段209个农户栽培的有机高粱产量和品质资料,采用气候曲面技术(ANUSPLI)方法得到各地段的温度、降水量和日照数据,并对各地段有机高粱产量和品质及原产地气象条件进行了相关分析.结果表明:气温日较差对高粱产量、单宁质量分数有显著影响;降水量对高粱产量、单宁和淀粉质量分数有显著性影响;日照时数对高粱产量、单宁和淀粉质量分数有显著影响;其中气温、降水量和日照对高粱单宁质量分数的影响都为显著负相关.气象条件对高粱蛋白质质量分数无明显影响.该文依据相关分析结果建立了气候区划指标,并做出了优质酒用有机高粱栽培基地的气候区划,其优质有机高粱栽培基地最适宜区在赤水河流域中段的贵州省仁怀市北部、西部和西南部地区,适宜区在仁怀市东部和南部地区. 相似文献
974.
利用替代法得到了复合指数形变幅杆的频率方程,在此基础上解算出谐振长度、放大系数等重要参数,并借助于ANSYS软件对复合变幅杆进行模态分析.结果表明该方法对复合形变幅杆的设计是可行的,也显示了ANSYS在变幅杆设计中的重要性.这给其他复合变幅杆的设计提供了参考. 相似文献
975.
为优化超声波法和酶解法提取菊花总黄酮的工艺,并比较其工艺条件,选择因素水平,采用L9(34)正交设计优化提取工艺,以芦丁为对照品,用紫外分光光度计分析其提取率.结果表明,酶解法最佳工艺条件为:25倍70%的乙醇溶液,酶添加量0.5%,于45℃水浴下酶解150min,得率为5.60%;超声波法最佳工艺条件为:10倍70%的乙醇溶液超声40min,提取3次,得率为4.61%.酶解法的得率比超声波法的高21.5%. 相似文献
976.
Recognizing the successes of treed Gaussian process (TGP) models as an interpretable and thrifty model for nonparametric regression,
we seek to extend the model to classification. Both treed models and Gaussian processes (GPs) have, separately, enjoyed great
success in application to classification problems. An example of the former is Bayesian CART. In the latter, real-valued GP
output may be utilized for classification via latent variables, which provide classification rules by means of a softmax function.
We formulate a Bayesian model averaging scheme to combine these two models and describe a Monte Carlo method for sampling
from the full posterior distribution with joint proposals for the tree topology and the GP parameters corresponding to latent variables at the leaves. We concentrate on efficient sampling of the latent variables,
which is important to obtain good mixing in the expanded parameter space. The tree structure is particularly helpful for this
task and also for developing an efficient scheme for handling categorical predictors, which commonly arise in classification
problems. Our proposed classification TGP (CTGP) methodology is illustrated on a collection of synthetic and real data sets.
We assess performance relative to existing methods and thereby show how CTGP is highly flexible, offers tractable inference,
produces rules that are easy to interpret, and performs well out of sample. 相似文献
977.
This paper proposes a maximum clustering similarity (MCS) method for determining the number of clusters in a data set by studying
the behavior of similarity indices comparing two (of several) clustering methods. The similarity between the two clusterings
is calculated at the same number of clusters, using the indices of Rand (R), Fowlkes and Mallows (FM), and Kulczynski (K)
each corrected for chance agreement. The number of clusters at which the index attains its maximum is a candidate for the
optimal number of clusters. The proposed method is applied to simulated bivariate normal data, and further extended for use
in circular data. Its performance is compared to the criteria discussed in Tibshirani, Walther, and Hastie (2001). The proposed
method is not based on any distributional or data assumption which makes it widely applicable to any type of data that can
be clustered using at least two clustering algorithms. 相似文献
978.
Nicol��s F. Lori 《Foundations of Science》2011,16(4):311-314
During the refereeing procedure of Anthropomorphic Quantum Darwinism by Thomas Durt, it became apparent in the dialogue between him and me that the definition of information in Physics is something about which not all authors agreed. This text aims at describing the concepts associated to information that are accepted as the standard in the Physics world community. 相似文献
979.
Robert C. Scharff 《Foundations of Science》2011,16(2-3):227-243
Interest the Erklären?CVerstehen debate is usually interpreted as primarily epistemological. By raising the possibility that there are fundamentally different methods for fundamentally different types of science, the debate puts into play all the standard issues??that is, issues concerning scientific explanation and justification, the unity and diversity of scientific disciplines, the reality of their subject matter, the accessibility of various subject matters to research, and so on. In this paper, however, I do not focus on any of these specific issues. I start instead from the fact that the very existence of the debate itself is an issue; in fact, it poses a philosophical problem that almost everyone but the hardest line logical empiricists has come to realize cannot be resolved epistemologically. In my view, however, that it cannot be resolved ontologically, either. I think the problem is at bottom hermeneutical, and its resolution requires that we focus first, not on the objects of science or the methods of studying them, but on the character of the philosophical orientation assumed by those who would try to resolve it. In this paper, I explain why I think this is so by analyzing (1) Dilthey??s contribution to the original debate, (2) Husserl??s reaction to Dilthey, and (3) Heidegger??s critical evaluation of both. This line of philosophical development??this movement of self-understanding from critiques of objectivism to hermeneutical phenomenology??is of course already a central feature of much work in continental philosophy of science. In my conclusion, however, I argue for the less well-established??even if apparently approved??idea that it ought to be a central feature of technoscience studies as well. 相似文献
980.
Carette JE Raaben M Wong AC Herbert AS Obernosterer G Mulherkar N Kuehne AI Kranzusch PJ Griffin AM Ruthel G Dal Cin P Dye JM Whelan SP Chandran K Brummelkamp TR 《Nature》2011,477(7364):340-343
Infections by the Ebola and Marburg filoviruses cause a rapidly fatal haemorrhagic fever in humans for which no approved antivirals are available. Filovirus entry is mediated by the viral spike glycoprotein (GP), which attaches viral particles to the cell surface, delivers them to endosomes and catalyses fusion between viral and endosomal membranes. Additional host factors in the endosomal compartment are probably required for viral membrane fusion; however, despite considerable efforts, these critical host factors have defied molecular identification. Here we describe a genome-wide haploid genetic screen in human cells to identify host factors required for Ebola virus entry. Our screen uncovered 67 mutations disrupting all six members of the homotypic fusion and vacuole protein-sorting (HOPS) multisubunit tethering complex, which is involved in the fusion of endosomes to lysosomes, and 39 independent mutations that disrupt the endo/lysosomal cholesterol transporter protein Niemann-Pick C1 (NPC1). Cells defective for the HOPS complex or NPC1 function, including primary fibroblasts derived from human Niemann-Pick type C1 disease patients, are resistant to infection by Ebola virus and Marburg virus, but remain fully susceptible to a suite of unrelated viruses. We show that membrane fusion mediated by filovirus glycoproteins and viral escape from the vesicular compartment require the NPC1 protein, independent of its known function in cholesterol transport. Our findings uncover unique features of the entry pathway used by filoviruses and indicate potential antiviral strategies to combat these deadly agents. 相似文献