Radio-immunologic determination of hypophyseal vasotocin by Phoxinus laevis during experimental modification of osmotic equilibrium]

Hypophysial vasotocin of Phoxinus laevis is determined by radio-immunoassay. With different sea water dilutions it is shown that hypophysial vasotocin concentration varies with ambient salinity. This fact agrees with histological pictures. Moreover, in comparison with the results of other authors, it is established that the hypophysial morphological modifications appeared only after the hormonal changes.     

Mycobacterial adjuvant and its carrier

Résumé Une fraction peptidoglycolipidique peut être extraite à partir du BCG par décapage acide dans un mélange de solvants fortement lipophiles. Cette fraction appelée ?LF? peut reproduire l'activité adjuvante du BCG entier dans les réactions immunitaires à médiation cellulaire et humorale. L'activité adjuvante du BCG appara?t comme liée à ce composant actif, LF, car après son extraction, le résidu bacillaire (BB) est dépourvu d'activité adjuvante. Néanmoins lorsque BB est utilisé pour adsorber (?véhiculer?) LF, le complexe BB-LF s'est révélé le meilleur adjuvant.

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This work was performed at the Laboratory of Experimental Hematology, Department of Zoology, the University of Nebraska-Lincoln, Lincoln, Nebraska 68508, USA.     

The effects of acetylation on the binding region of cartilage proteoglycans to hyaluronic acid

Summary Proteoglycans in cartilage are found as aggregates and as monomers. Evidence has been obtained indicating that hyaluronic acid, normally present in this tissue, binds together monomers into large molecular weight aggregates. In this investigation, the interacting region of the protein backbone has been studied. The results unequivocally demonstrated that the epsilon amino groups of lysine are involved in hyaluronic acid binding to proteoglycans and that their blocking by acetylation either prevents reaggregation or disaggregates the high mol. w aggregates.Supported by a grant from the Consiglio Nazionale delle Ricerche, Rome, Italy, and U. S. P. H. S., grants DE-02670 and HL 11310.     

Role of a free-living amoeba from water, Acanthamoaba castellani, in the transport of naked or enveloped animal viruses

The trophozo?ts of Acanthamoeba castellanii are unable to adsorb poliovirus or vesicular stomatitis Virus. After encystment in medium containing respectively 5.4 x 10(8) and 3 x 10(9) P.F.U./ml cysts did not contain Viruses. These data do not agree with a current hypothesis by which water's free Amoeba could carry animal Viruses.     

Presentation and automatic treatment of evolutive data in medicine. Application to clinical pancreatic pathology]

In this paper we propose a method allowing the representation of time-dependent changes in symptomatology. In algorithm, which automatically generates the sequence of stable states in patient's symptomatology evolution, describes slow, as well as fast, variations of diseases. This sequential representation of data can then be analysed by classical statistical procedures in a population of patients suffering from pancreatic diseases, to estimate the rate of global modification of clinical symptomatology in time.     

Stimulation of the secretion of LH and FSH and increase in testicular weight at birth in rats]

The evolutions of serum LH and FSH concentrations and of testicular weight have been measured in the newborn Rat before, during and up to 24 hrs. after birth. A sudden and transient increase of LH and FSH is observed at birth. The testicular weight rises rapidly between 2 and 4 hrs.