二十二碳六烯酸乙酯对沙土鼠缺血再灌注脑损伤及水肿作用的研究

研究二十二碳六烯酸乙酯(E-DHA)对沙土鼠缺血再灌注脑损伤及其脑水肿的影响.选用雄性断奶沙土鼠灌胃给予二十二碳六烯酸乙酯(150 mg/(kg·d))或等体积溶媒10周,阻断沙土鼠双侧颈总动脉血流10 min,造成缺血再灌注模型;测定再灌注后脑组织中丙二醛(MDA)水平,还原型谷胱甘肽(GSH)含量,超歧化氧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-PX)和钾、钠-ATP酶(Na ,K -ATPase)活性,脑水含量,钠、钾离子浓度及海马CA1区神经细胞存活百分数.结果表明:E-DHA预处理显著降低缺血再灌注沙土鼠脑组织MDA水平,阻止GSH含量、GSH-PX和Na ,K -ATPase活性下降,而对SOD的活性未表现出明显作用;E-DHA亦调节缺血再灌注沙土鼠脑组织钠、钾离子浓度,减轻缺血再灌注所致的脑水肿和神经细胞死亡.提示E-DHA对脑缺血再灌注脑损伤有显著保护作用,机制可能其与抗氧化作用有关.     

对流边界层顶部夹卷速度参数化的分析研究

应用 1979年 7月美国CIRCE试验边界层观测资料对两个夹卷速度参数化方案进行了对比验证 ,结果表明 :基于简单夹卷层结构模型的参数化方案we/w =A·Ri- 1 只适用于自由对流边界层 ,当对流边界层中存在较强机械湍流时 ,该方案变得不再适用 ;而基于“侵吞模型”的参数化方案we/w =B·θ /(Γzi)则不仅适用于自由对流边界层 ,对于含有较强机械湍流的对流边界层也能较好地符合 ,因而具有较强的适用性 .当对流边界层受机械湍流和浮力湍流共同驱动时 ,仅以浮力对流速度w 表征混合层垂直湍流速度尺度是不恰当的 ,还应该包含机械湍流的贡献 .对比验证表明 ,这一改进非常有效 ,不仅使物理意义更加合理 ,也使夹卷速度参数化方案与实际大气状况符合得更好     

兽药添加剂喹乙醇对水生生物的毒理学研究

兽药添加剂喹乙醇是一种在畜禽及水产养殖中应用广泛的促生长剂 ,但其安全性仍存在较大争议 ,使用不当或过量使用会对环境构成潜在危害 .采用斑马鱼和鲤鱼作为生物材料 ,分别研究了兽药添加剂喹乙醇对斑马鱼的急性毒性、对斑马鱼胚胎发育的影响及对鲤鱼肾细胞DNA的损伤 .急性毒性试验表明 ,96hrLC50 为 1 996.87mg/L ;胚胎发育试验实验结果表明 ,96hrEC50 为2 2 1 .2 0mg/L ;单细胞凝胶电泳试验结果表明 ,喹乙醇能引起较大的DNA损伤 ,与空白对照相比有极显著性差异 (P <0 .0 1) ,并在设定的剂量范围内呈现一定的剂量效应关系     

风对导弹飞控系统可靠性影响的仿真研究

可靠性是导弹的一项重要设计指标，风速矢量的变化是引起弹道散布的重要因素之一，而计算机仿真用于复杂系统的可靠性分析是一种有效的途径，因此采取仿真的手段来分析风对导弹飞控系统可靠性的影响。首先是建立风的工程化模型并进行随机化处理形成仿真模型；进一步研究风对导弹飞控系统的影响原理，进行导弹动力学模型的改造；接着详细阐述了可靠性的仿真算法，并给定了相关可靠性指标的计算公式；最后以某型导弹飞控系统为案例进行可靠性仿真试验验证。     

求解非结构四边形二次拉格朗日有限元方程的代数多重网格法

针对一类带间断系数的椭圆边值问题,在非结构四边形部分下,讨论了两种二次拉格朗日有限元方程的代数多重网格法,通过利用双线性元和二次元基函数之间的表示关系,给出了一种新的网格粗化算法和构造提升算子的代数途径.数值实验表明:新的AMC法具有更好的“鲁棒”性和效率.     

三苯基锡印迹聚合物的合成及吸附性能

以壳聚糖为聚合物单体，以三苯基锡(TPT)为模板分子，制备在空间结构和结合位点上与TPT完全匹配的TPT模板交联壳聚糖分子印迹聚合物(TMlPCLC)，研究该分子印迹聚合物的吸附、交联和洗脱条件。以及对TPT的吸附能力．结果表明，所合成TMIPCLC对TPT具有良好的吸附选择性。     

The Application of Similarity Theory in Designing Large Deflection Buckling Spring-Piece

Large Deflection Buckling Spring-Piece (LDBSP) refers to the deformation of an end-fixed flat spring-piece under normal loadings. Plastic deformation usually appears in LDBSP.The static characteristic curve is very particular, because within its linear deflection region, the spring constant can be designed to be any value from minus to plus. With its obvious advantages of large liner deflection range, low spring constant, etc., the LDBSP has now been extensively applied to the exciting device, low-frequency shock absorbers and so on. The static characteristic curve of LDBSP belongs to the nonlinear problem of an arch with varying section. Therefore, it is difficult to obtain it theoretically. The formulae for designing LDBSP have not been set up yet. In this study,the authors apply similarity theory to analyze the liner deflection range A and the spring constant K, and derive the relationship of similarity criterion, finally obtain a set of formulae for designing LDBSP by model test and the least square method, which can be applied in engineering design.Through the research, it is proved that it is unnecessary to keep geometrical similarity of spring-piece shape. This fact extends the application scope of the formulae. The proposed formulae for designing LDBSP thereby can be applied for any dimensions within the range allowed.     

THE EFFECT OF ALUM AND METALS ON PAPER AGING

Books and archives experience aging which is affected by a variety of factors, such as microorganism, humidity, light and components of paper [1]. Thus, the studies concerning impacts of those factors on paper aging are required. In this paper, an accelerated paper aging was carried out to investigate the effects of acid and metals such as alum, copper ( Ⅱ ) sulfate, copper ( Ⅱ ) chloride, and iron (Ⅲ) chloride on paper aging. It was found that both acid and metals had impacts on paper aging. In particular, paper aging was far more accelerated in case that acid and metals were present in paper at the same time.     

Research ＆ Development of Grade X70 LSAW Steel Pipes for West-East Gas Pipeline

In this article the research and development of X70 large diameter longitudinal seam submerged arc welded (LSAW) steel pipes for West-East Gas Transportation Pipeline project (WEGTP) in China are introduced, including the key technique, fabrication of pipe production line, mass production and the latest progress of LSAW steel pipe technique.     

基于认证和加密技术的安全多媒体传输方案

本文提出一种安全可靠的多媒体传输方案 ,将多媒体编码过程与认证过程相结合 ,信道编码过程与加密过程相结合 ,既实现了对多媒体敏感区域的认证功能 ,又实现了对整个数据流的加密保护 .其中 ,认证过程对敏感数据进行数字签名 ,并将此签名嵌入敏感区域 ,它可以检测出恶意篡改或传输错误 ;信道编码加密过程是将纠错编码与混沌流密码相结合 ,同时具有纠错功能和加密功能 .理论分析可见 ,认证和加密过程都与编码过程相结合 ,计算复杂度低 ,而且保持了信道编码的容错能力 .实验结果表明 ,此方案具有较高的安全性 ,适合多媒体数据的安全传输 .