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301.
W. D. MacRae G. F. Q. Chan Chi-Kit Wat G. H. N. Towers J. Lam 《Cellular and molecular life sciences : CMLS》1980,36(9):1096-1097
Summary -Terthienyl and 5 polyacetylenes were examined for chromosome damaging activity using Syrian hamster cells. None of these naturally occurring compounds induced sister chromatid exchanges and neither -terthienyl nor phenylheptatriyne induced chromosome aberrations.The authors wish to thank the National Science and Engineering Research Council for financial support of this research. 相似文献
302.
Summary
-adrenoceptor stimulation by isoprenaline increases the potassium efflux in beating guinea-pig atria. This effect is not mimicked by 8-bromo-cyclic AMP, a cyclic AMP analogue which exerts a positive inotropic effect in this preparation. 相似文献
303.
Summary After a dose of 3.0 Gy in the peak position of the pion depth-dose curve, the ratios between observed chromosome aberration yields under conditions of oxygenation and of anoxia were obtained for lymphocytes exposed at 3 depths in a plastic phantom. These ratios were 3.7, 1.9 and 1.3 in the plateau, peak and post-peak positions, respectively, suggesting a corresponding decrease in the oxygen enhancement ratio.Acknowledgments. We wish to thank Dr D.H. Reading, Mr M.A. Hynes and Mr W. Spinks for their assistance at the Rutherford Laboratory's -II beam line. This work was partly supported by Euratom Contract 171-76-1 BIO-UK. 相似文献
304.
D. V. Amin R. B. Doctor A. O. Girdhar U. H. Shah 《Cellular and molecular life sciences : CMLS》1980,36(12):1410-1411
Summary Prostaglandin (PG) release was measured from the isolated perfused rabbit heart. The effects of -adrenergic stimulation and blockade suggest that PG synthesis is regulated in part by adrenergic mechanisms. 相似文献
305.
M. K. Agarwal J. Paillard M. Philippe 《Cellular and molecular life sciences : CMLS》1980,36(8):1010-1012
Summary Contrary to the techniques of mere association, column chromatography has revealed a protoreceptor that accepts aldosterone agonists and antagonists only in the physiological target, the kidney, and is absent in non-targets, liver and serum; it is furthermore different from the aldosterone specific receptor in renal cytosol.Supported in part by grants from the CNRS AI 03 1917 and UER Broussais Hôtel Dieu. 相似文献
306.
307.
M. J. Kelly 《Cellular and molecular life sciences : CMLS》1981,37(8):889-890
Summary The relaxant effects of isoprenaline on rabbit isolated renal artery and aorta were compared. The results suggest that although isoprenaline acts on -adrenoceptors in the aorta it stimulates dopamine receptors in the renal artery. 相似文献
308.
H. Watanabe J. A. Menzies J. C. K. Loo 《Cellular and molecular life sciences : CMLS》1981,37(8):883-884
Summary Isonicotinic acid hydrazide (isoniazid) was shown to react readily with 17-ethinyl-17-hydroxyestr-4-en-3-one (norethindrone) to form the isonicotinyl hydrazone of the steroid under conditions likely to exist in the stomach. The hydrazone was detected in guinea-pig, but not rat, plasma following its oral administration. Rat liver tissue metabolized the compound more rapidly than guinea-pig liver in vitro which probably accounts for the failure to detect the hydrazone in rat plasma. 相似文献
309.
D. Sabourault Françoise Bauché Y. Giudicelli J. Nordmann R. Nordmann 《Cellular and molecular life sciences : CMLS》1981,37(3):227-229
Summary After 3 weeks of continuous ethanol intoxication by inhalation, the maximal number and affinity of the -and -receptors of rat heart were unchanged. These data indicate that adrenergic receptor disturbances are not involved in the mechanism of chronic ethanol-induced triglyceride deposition in the heart.Acknowledgments. This work was supported by grants from the Institut National de la Santé et de la Recherche Médicale. We wish to thank Mr M. Clément for skilled technical assistance in performing chronic ethanol inhalation treatments. 相似文献
310.
E. Knecht J. Renau-Piqueras J. Hernández-Yago S. Grisolía 《Cellular and molecular life sciences : CMLS》1981,37(5):456-457
Summary Protein from resting or phytohemagglutinin-stimulated human peripheral blood T-lymphocytes, pulse-labeled in vitro for 1 h with3H-leucine, had a half-life of 30 h. 相似文献