排序方式: 共有27条查询结果,搜索用时 15 毫秒
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In this article we seek to lay bare a couple of potential conceptual and methodological issues that, we believe, are implicitly present in contemporary philosophy of technology (PhilTech). At stake are (1) the sustained pertinence of and need for coping strategies as to ‘how to live with technology (in everyday life)’ notwithstanding PhilTech’s advancement in its non-essentialist analysis of ‘technology’ as such; (2) the issue of whether ‘living with technology’ is a technological affair or not (or both); and (3) the tightly related question concerning the status of the methodological bedrock of contemporary PhilTech, the ‘empirical turn.’ These matters are approached from the perspective of the philosophical notion of the ‘art of living,’ and our argumentation is developed both as a context for and on the basis of the contributions to the special issue ‘The Art of Living with Technology.’ 相似文献
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Scheper GC van der Klok T van Andel RJ van Berkel CG Sissler M Smet J Muravina TI Serkov SV Uziel G Bugiani M Schiffmann R Krägeloh-Mann I Smeitink JA Florentz C Van Coster R Pronk JC van der Knaap MS 《Nature genetics》2007,39(4):534-539
Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation (LBSL) has recently been defined based on a highly characteristic constellation of abnormalities observed by magnetic resonance imaging and spectroscopy. LBSL is an autosomal recessive disease, most often manifesting in early childhood. Affected individuals develop slowly progressive cerebellar ataxia, spasticity and dorsal column dysfunction, sometimes with a mild cognitive deficit or decline. We performed linkage mapping with microsatellite markers in LBSL families and found a candidate region on chromosome 1, which we narrowed by means of shared haplotypes. Sequencing of genes in this candidate region uncovered mutations in DARS2, which encodes mitochondrial aspartyl-tRNA synthetase, in affected individuals from all 30 families. Enzyme activities of mutant proteins were decreased. We were surprised to find that activities of mitochondrial complexes from fibroblasts and lymphoblasts derived from affected individuals were normal, as determined by different assays. 相似文献
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Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers 总被引:21,自引:0,他引:21
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Postphenomenology and the Politics of Sustainable Technology 总被引:3,自引:3,他引:0
Gert Goeminne 《Foundations of Science》2011,16(2-3):173-194
In this paper I argue that Don Ihde??s ??postphenomenology?? may constitute a proper access to the question concerning sustainable technology and I do so in three steps. First, I lay bare how a modern framework that systematically separates facts and instruments from values, choices and responsibilities yields no space for engaged decisions and responsible action towards more sustainable societies. In a second step, I elaborate how postphenomenology??s ??in-between?? perspective opens up the possibility of questioning science and technology as an inherent part of our human existence. Building on this, I argue how a ??normativity of the in-between?? may be developed around the concept of ??topical measure?? and which is grounded in the foundationless foundation of postphenomenology??s relational ontology. In a last step, I show how such a ??topical measure?? opens up two fields of normative action vis-à-vis the question concerning sustainable technology: one critical, the other empowering. Whereas ??topical criticism?? focuses on bringing into the open the powerful subpolitics of science and technology, the field of ??topical responsibility?? rather aims at actively assuming responsibility in these political circles. Besides its main interest, which lies in forging a genuine and adequate way into the issue of sustainability, this paper also constitutes an entry into Ihde??s philosophical oeuvre. The question concerning sustainable technology does not only touch upon Ihde??s relational trinity human-technology-world, it also deals with the degree of normative inquiry present in Ihde??s philosophy, an issue he has been repeatedly questioned about by his interlocutors. 相似文献
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de Vries W Solberg S Dobbertin M Sterba H Laubhahn D Reinds GJ Nabuurs GJ Gundersen P Sutton MA 《Nature》2008,451(7180):E1-3; discussion E3-4
Magnani et al. present a very strong correlation between mean lifetime net ecosystem production (NEP, defined as the net rate of carbon (C) accumulation in ecosystems) and wet nitrogen (N) deposition. For their data in the range 4.9-9.8 kg N ha(-1) yr(-1), on which the correlation largely depends, the response is approximately 725 kg C per kg N in wet deposition. According to the authors, the maximum N wet deposition level of 9.8 kg N ha(-1) yr(-1) is equivalent to a total deposition of 15 kg N ha(-1 )yr(-1), implying a net sequestration near 470 kg C per kg N of total deposition. We question the ecological plausibility of the relationship and show, from a multi-factor analysis of European forest measurements, how interactions with site productivity and environment imply a much smaller NEP response to N deposition. 相似文献
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Albertus H. Olivier Gert C. van Rooyen Berthold Firmenich Karl E. Beucke 《清华大学学报》2008,13(Z1):165-170
Currently, some commercial software applications support users to work in an integrated environment. However, this is limited to the suite of models provided by the software vendor and consequently it forces all the parties to use the same software. In contrast, the research described in this paper investigates ways of using standard software applications, which may be specialized for different professional domains. These are linked for effective transfer of information and a binding mechanism is provided to support consistency. The proposed solution was implemented using a CAD application and an independent finite element application in order to verify the theoretical aspects of this work. 相似文献