The effect of D-6-methyl-8-[β-isopropylaminoethyl] ergoline-I on the lactation in nursing rats

D-6-Methyl-8-[-isopropylaminoethyl] ergoline-I [VÚFB-10726], beginning from the dose of 0.05 mg/kg p.o., suppresses lactation through the inhibition of prolactin secretion in nursing rats.     

Ecdysone 20-hydroxylase from the midgut of the tobacco hornworm (Manduca sexta L.)

Summary An ecdysone 20-hydroxylase enzyme system that converts -ecdysone to 20-hydroxyecdysone was prepared from the midgut of the tobacco hornworm prepupa. This partially purified enzyme is NADPH dependent and is localized in the mitochondrial fraction of the midgut tissue.     

Holocene lake deposits of Bosten Lake, southern Xinjiang, China

A 9.25-m-long sediment core from Bosten Lake,Xinjiang, provides detailed information about changes in the water budget and biological acticity over the last 8400 cal-endar years. The chronology is constructed from six AMS radiocarbon dates on the terrestrial plant remains. Based onanalyses of TOC, CO3, detrital compounds and biogenic SiO2,lake level fluctuations and periods of remarkably-negative water budget appeared at 8.4-8.2 cal ka, 7.38-7.25 cal ka,5.7-5.5 cal ka, 3.7-3.4 cal ka and 3.3-2.9 cal ka, respec-tively. As they are in-phase with low lake levels at Sumxl Co and Bangong Co in western Tibet Plateau and with paleo-lakes in Inner Mongolia, a climate-induced change to some-what drier and warmer conditions is inferred. A further drop in lake level after 1320 AD of about 200 yr duration may heattributed to a negative water balance prior to the main phase of the Little Ice Age. Deep and stable lake phases of 1500 yr and 1800 yr duration at 7.2-5.7 cal ka and 5.5-3.7cal ka coincide with maximum moisture during the Holocene Megathermai in China. The long term trend towards aridity since about 4.3 cal ka can dearly be recognised. The reduced water budget of Bosten Lake from 640-1200 AD may be attributed to local effects.     

Ni2MnGa铁磁形状记忆材料

铁磁形状记忆合金 (FSMA)是在一定温度范围马氏体相稳定同时又具铁磁性的一类特殊的形状记忆合金。Ni2MnGa铁磁形状记忆合金近年来成为呈现磁场驱动大应变的新型驱动材料 ,这些应变来自磁场诱发马氏体孪晶的重排 ,而不是磁场对奥氏体至马氏体相变的作用。孪晶变体的重排在宏观上呈现为正或切应变 ,一非化学计量比Ni2 MnGa单晶于室温加 0 .4T磁场能产生6 %的应变 ,Ni Mn Ga单晶在高至 15 0Hz的交变磁场仍可得到 2 .5 %的应变。本文阐述了与这种磁控形状记忆效应相关的孪晶界迁动的磁学和晶体学理论。马氏体相的大磁晶各向异性能使磁化沿c轴方向有利 ,穿过孪晶界c轴刚好转动 90度 ,同时 ,这个孪晶界也构成了约 90度的畴界。在各向异性的情况下 ,孪晶界的迁动仅有相邻孪晶变体的Zeeman能差驱动 ,μ0 ΔMis·Hi。磁场和外应力对应变的影响通过对一简单的自由能表达式取极小值来表示 ,自由能表达式包括Zeeman能、磁晶各向异性能和外应力以及在某些情况下需考虑的内部弹性能 ,模型的所有参数可通过应力 应变曲线和磁化曲线测量得到。铁磁形状记忆合金的磁场诱发应变可类比传统热弹性形状记忆效应 ,与更为人们所熟知的磁致伸缩现象不同。     

五台山滹沱群SHRIMP锆石U-Pb年龄: 华北克拉通早元古代拼合新证据

采自五台山台怀镇南8 km处滹沱群变质火山-沉积岩层中的长英质凝灰岩样品含有两组锆石, 所记录的SHRIMP锆石方法²⁰⁷Pb/²⁰⁶Pb年龄分别为2180±5 Ma和2087±9 Ma. 在误差范围内, 较老的一组年龄与五台山大洼梁花岗岩年龄相当, 表明它们来自相似的地壳岩浆源; 而较年轻的一组锆石年龄与相邻地区阜平杂岩湾子表壳岩中变沉积岩和变火山岩及南营花岗片麻岩年龄相当, 因而被解释为滹沱群火山作用年龄. 这两组年龄的存在表明: (1) 滹沱群形成于早元古代而非太古宙; (2) 早元古代火山-沉积作用在五台和阜平地区同时间发生. 这样, 早元古代沉积作用在该区是广泛的, 它们代表了华北克拉通东部陆块西侧大陆边缘相沉积. 滹沱群火山作用年龄的确定也表明该群所经历的变质-变形事件发生在2087±9 Ma 之后, 这进一步佐证我们最近根据其他方面研究结果所得出的吕梁造山事件(约1.8 Ga)是该区主要构造事件的结论: 该事件导致华北克拉通东部陆块和西部陆块的最终拼合, 并成为全球早-中元古代超级大陆组成部分之一.     

近红外光谱技术鉴别海面溢油

近红外光谱技术分析速度快、效率高、成本低、重现性好,典型的无损分析;主要用于样品类别鉴定和纯度检验.近红外光谱技术结合模式识别方法,在纯品油种类的鉴别中已得到成功应用[1,2],本实验室也初步建立了纯品油近红外谱图数据库[3],但该法在实际海面溢油样品的鉴别中应用仍甚少.     

正常赖默—悌曼反应研究:超声波辐射与相转移催化合成方法

系统研究了正常及反常赖政－悌曼反应（NormalorAbnormalReliner－TiemannReavction，NRYorART）；研究了相转移住化方法和超声波辐射技术及其在正常Reliner—Tiemann（NRT）反应中的应用，从而使反应条件温和，效率增加，对邻比大，时间缩短，取得较好收效。     

Induction of autotomy in the American bird grasshopperSchistocerca americana (Drury) by the ecdysone agonist RH-5849 and investigation of its mode of action

The non-steroidal ecdysone agonist RH-5849 (1,2-dibenzoyl-l-tert-butylhydrazine) was found to be an effective neurotoxicant on injection into the American bird grasshopper,Schistocerca americana (Drury). Treated grasshoppers became immediately hyperactive, followed by loss of coordination, paralysis and eventually death. We also discovered that this compound induced bilateral autotomy of the metathoracic legs during the early stages of intoxication. However, no evidence of ecdysonergic or morphogenetic activities was observed. Synergism studies with neurotoxins of known mode of action suggested that RH-5849 has a mechanism of action similar to that of 4-amino pyridine, which blocks potassium channels.