低成本教育型机器人控制器的设计与实现

论述了一种低成本机器人控制器的设计与实现 .采用AT89C2 0 5 1作为主芯片 ,提供两路独立的电机驱动和最多 7个外围扩展口 .软件采用汇编语言编写 ,能下载并运行上位机程序 ,配合外围红外传感器 ,实现了追踪和安全漫游 .     

基于集对分析的模糊逻辑研究

介绍了一种新的解决模糊问题的途径 ,提出了一种模糊逻辑表示新形式 ,论证了其较之于传统模糊逻辑表示法的优点 .     

基于PowerBuilder的电子邮件应用设计与实现

阐述了在PowerBuilder的应用程序中 ,实现嵌入电子邮件的一般原理、方法及具体的程序实现 ,使PowerBuilder应用程序能够访问与MAPI兼容的电子邮件系统 .该邮件应用的特点在于能在应用软件系统中自动发送和接收电子邮件 ,同时还能获得地址薄的信息 .该邮件应用模块可挂接在任意PowerBuilder应用软件中 ,具有一定实用价值 .     

国际单项体育联合会善治评价体系构建及其实证研究

基于治理理论和委托—代理模型,本研究以35 个国际单项体育联合会善治 评价为对象,设计了以透明度、程序民主、制衡、团结等维度作为关键维度的指标体系, 并使用文献资料法、问卷调查法和访谈法等方法,对数据进行搜集整理。研究发现,国 际单项体育联合会平均得分为45.5（满分100）,善治状况评价为“一般”,决策和工作 机制不透明、选举和工作程序失范、利益相关者参与不足等,导致组织内部投机主义盛 行,国际单项体育联合会合法性面临危机。研究建议：1）严格执行选举程序,健全主席 和高管资格审查机制;2）完善信息公开制度,提升组织透明度;3）规范工作流程,充 实组织行政程序正当性;4）多元主体参与,健全组织内外部审查制度;5）明确最长任 期,保证组织官员积极性。     

Nanoengineering of amino - functionalized mesoporous silica nanospheres as nanoreactors

Selective functionalization of mesoporous silica nanospheres (MSNs) is crucial for nanoengineering of MSNs. Herein, we have combined “surface-protected etching strategy” and “cationic surfactant assisted etching strategy” to prepare functionalized MSNs with externally attached amino groups. The externally attached NH2 groups endow the catalysts with excellent catalytic performance for nitroaldol reaction between nitromethane and benzaldehyde. In addition, those NH2-MSNs can also be used to support gold nanoparticles, which display very good catalytic performance for reduction of 4-nitrophenol. It can be envisioned that the synthesis protocol developed in this work could also be extended to nanoengineered MSNs, which provides opportunities for nanoreactors design.     

Swimming and bipedal bottom-running in the pig-nosed turtle Carettochelys insculpta Ramsay, 1886

The pig-nosed freshwater turtle Carettochelys insculpta Ramsay, 1886 has paddle-shaped foreflippers that resemble those of sea turtles. These turtles exhibit a wide range of swimming capabilities. As well as swimming by the action of synchronized foreflippers alone, they sometimes used alternate hindlimb action at the same time. They could swim by ipsilaterally synchronized action of all four limbs, or by hindlimb action alone (combined with stabilizer/lift function of the foreflippers). The turtles also showed flexibility in bottom-walking. Besides the ipsilaterally synchronized quadrupedal action characteristic of other freshwater turtles, they exhibited a bipedal walking mechanism never previously described. Propelled by alternate action of the hindlimbs, the animals held the head and plastron above the substratum, with the large foreflippers acting to provide anterior lift and stability against roll and yaw. Because both hindlimbs were sometimes off the substratum simultaneously during bipedal locomotion, their duty factors were < 0.5, implying a bipedal run.     

Disruption of calcitonin gene-related peptide signaling accelerates muscle denervation and dampens cytotoxic neuroinflammation in SOD1 mutant mice

Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease. Neuronal vacuolization and glial activation are pathologic hallmarks in the superoxide dismutase 1 (SOD1) mouse model of ALS. Previously, we found the neuropeptide calcitonin gene-related peptide (CGRP) associated with vacuolization and astrogliosis in the spinal cord of these mice. We now show that CGRP abundance positively correlated with the severity of astrogliosis, but not vacuolization, in several motor and non-motor areas throughout the brain. SOD1 mice harboring a genetic depletion of the βCGRP isoform showed reduced CGRP immunoreactivity associated with vacuolization, while motor functions, body weight, survival, and astrogliosis were not altered. When CGRP signaling was completely disrupted through genetic depletion of the CGRP receptor component, receptor activity-modifying protein 1 (RAMP1), hind limb muscle denervation, and loss of muscle performance were accelerated, while body weight and survival were not affected. Dampened neuroinflammation, i.e., reduced levels of astrogliosis in the brain stem already in the pre-symptomatic disease stage, and reduced microgliosis and lymphocyte infiltrations during the late disease phase were additional neuropathology features in these mice. On the molecular level, mRNA expression levels of brain-derived neurotrophic factor (BDNF) and those of the anti-inflammatory cytokine interleukin 6 (IL-6) were elevated, while those of several pro-inflammatory cytokines found reduced in the brain stem of RAMP1-deficient SOD1 mice at disease end stage. Our results thus identify an important, possibly dual role of CGRP in ALS pathogenesis.