Mannosidohydroxystreptomycin fromStreptomyces sp.

Riassunto Viene descritto l'isolamento e lo studio chimico della mannosidoossistreptomicina, presente, insieme con ossistreptomicina, streptidina e toiocamicina, nelle colture delloStreptomyces 86. Il nuovo antibiotico ed il suo diidroderivato presentano una attività antibatterica paragonabile a quella di streptomicina e di ossistreptomicina.     

Adrenal lipid and plasma corticosterone depletion after 7,12-dimethylbenz(a)anthracene administration to the albino rat

Zusammenfassung Fluorometrische Messungen zeigten eine Abnahme von Plasmacorticosterone (CCS). Die Bedeutung dieser Resultate für theoretische Aspekte der Karzinogenese wird diskutiert.     

On the possible existence of muscarinic cholinoreceptors on the postsynaptic membrane of the frog muscle

Zusammenfassung An den postsynaptischen Muskelzellmembranen werden Befunde erhoben, welche darauf hinweisen, dass qualitativ keine Differenzierung zwischen muskarin- und nikotinartigen Rezeptoren möglich ist.     

Kompensation der teratogenen Wirkung eines Thalidomid-Metaboliten durchl-Glutaminsäure

Summary Skeletal defects were observed in the off-spring of SWS-mice following i.p. administration of phthaloyl-l-glutamic acid, a metabolite of thalidomide. The fetuses of animals which receivedl-glutamic acid in addition to the teratogenic drug, did not show any malformations, whereas concurrent i.p. administration of thed-isomer of glutamic acid failed to reverse teratogenicity induced by phthaloyl-l-glutamic acid.