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71.
72.
An unresolved issue in cortical development concerns the relative contributions of intrinsic and extrinsic factors to the functional specification of different cortical areas. Ferrets in which retinal projections are redirected neonatally to the auditory thalamus have visually responsive cells in auditory thalamus and cortex, form a retinotopic map in auditory cortex and have visual receptive field properties in auditory cortex that are typical of cells in visual cortex. Here we report that this cross-modal projection and its representation in auditory cortex can mediate visual behaviour. When light stimuli are presented in the portion of the visual field that is 'seen' only by this projection, 'rewired' ferrets respond as though they perceive the stimuli to be visual rather than auditory. Thus the perceptual modality of a neocortical region is instructed to a significant extent by its extrinsic inputs. In addition, gratings of different spatial frequencies can be discriminated by the rewired pathway, although the grating acuity is lower than that of the normal visual pathway. 相似文献
73.
Hobmayer B Rentzsch F Kuhn K Happel CM von Laue CC Snyder P Rothbächer U Holstein TW 《Nature》2000,407(6801):186-189
74.
Infection by porcine endogenous retrovirus after islet xenotransplantation in SCID mice 总被引:56,自引:0,他引:56
van der Laan LJ Lockey C Griffeth BC Frasier FS Wilson CA Onions DE Hering BJ Long Z Otto E Torbett BE Salomon DR 《Nature》2000,407(6800):90-94
75.
76.
Colloidal suspensions that form periodic self-assembling structures on sub-micrometre scales are of potential technological interest; for example, three-dimensional arrangements of spheres in colloidal crystals might serve as photonic materials, intended to manipulate light. Colloidal particles with non-spherical shapes (such as rods and plates) are of particular interest because of their ability to form liquid crystals. Nematic liquid crystals possess orientational order; smectic and columnar liquid crystals additionally exhibit positional order (in one or two dimensions respectively). However, such positional ordering may be inhibited in polydisperse colloidal suspensions. Here we describe a suspension of plate-like colloids that shows isotropic, nematic and columnar phases on increasing the particle concentration. We find that the columnar two-dimensional crystal persists for a polydispersity of up to 25%, with a cross-over to smectic-like ordering at very high particle concentrations. Our results imply that liquid crystalline order in synthetic mesoscopic materials may be easier to achieve than previously thought. 相似文献
77.
Doron-Mor I Hatzor A Vaskevich A van der Boom-Moav T Shanzer A Rubinstein I Cohen H 《Nature》2000,406(6794):382-385
Probing the structure of material layers just a few nanometres thick requires analytical techniques with high depth sensitivity. X-ray photoelectron spectroscopy (XPS) provides one such method, but obtaining vertically resolved structural information from the raw data is not straightforward. There are several XPS depth-profiling methods, including ion etching, angle-resolved XPS (ref. 2) and Tougaard's approach, but all suffer various limitations. Here we report a simple, non-destructive XPS depth-profiling method that yields accurate depth information with nanometre resolution. We demonstrate the technique using self-assembled multilayers on gold surfaces; the former contain 'marker' monolayers that have been inserted at predetermined depths. A controllable potential gradient is established vertically through the sample by charging the surface of the dielectric overlayer with an electron flood gun. The local potential is probed by measuring XPS line shifts, which correlate directly with the vertical position of atoms. We term the method 'controlled surface charging' and expect it to be generally applicable to a large variety of mesoscopic heterostructures. 相似文献
78.
Subduction erosion along the Middle America convergent margin 总被引:5,自引:0,他引:5
'Subduction erosion' has been invoked to explain material missing from some continents along convergent margins. It has been suggested that this form of tectonic erosion removes continental material at the front of the margin or along the underside of the upper (continental) plate. Frontal erosion is interpreted from disrupted topography at the base of a slope and is most evident in the wake of subducting seamounts. In contrast, structures resulting from erosion at the base of a continental plate are seldom recognized in seismic reflection images because such images typically have poor resolution at distances greater than approximately 5 km from the trench axis. Basal erosion from seamounts and ridges has been inferred, but few large subducted bodies--let alone the eroded base of the upper plate--are imaged convincingly. From seismic images we identify here two mechanisms of basal erosion: erosion by seamount tunnelling and removal of large rock lenses of a distending upper plate. Seismic cross-sections from Costa Rica to Nicaragua indicate that erosion may extend along much of the Middle America convergent margin. 相似文献
79.
Gloeckler G Geiss J Schwadron NA Fisk LA Zurbuchen TH Ipavich FM von Steiger R Balsiger H Wilken B 《Nature》2000,404(6778):576-578
Remote sensing observations and the direct sampling of material from a few comets have established the characteristic composition of cometary gas. This gas is ionized by solar ultraviolet radiation and the solar wind to form 'pick-up' ions, ions in a low ionization state that retain the same compositional signatures as the original gas. The pick-up ions are carried outward by the solar wind, and they could in principle be detected far from the coma (Sampling of pick-up ions has also been used to study interplanetary dust, Venus' tail and the interstellar medium.) Here we report the serendipitous detection of cometary pick-up ions, most probably associated with the tail of comet Hyakutake, at a distance of 3.4 AU from the nucleus. Previous observations have provided a wealth of physical and chemical information about a small sample of comets, but this detection suggests that remote sampling of comet compositions, and the discovery of otherwise invisible comets, may be possible. 相似文献
80.
Phylogenetic position of sponges in early metazoan evolution and bionic applications of siliceous sponge spicules 总被引:1,自引:0,他引:1
Werner E G MULLER WANG XiaoHong ZENG LingSen Heinz C SCHRODER 《科学通报(英文版)》2007,52(22):3029-3040
Sponges are the oldest and the simplest but not primitive multicellular animals. They represent the earliest evolutionary metazoan phylum still extant. It was a long and painful scientific process to posi-tion the most enigmatic and mysterious metazoan,the Porifera,into their correct phylogenetic place among the eukaryotes in general and multicellular animals in particular. As living fossils,sponges provide the best evidence for the early evolution of Metazoa. More recently,interest has been focused on the bionic applications of sponges' siliceous spicules,after the discovery of their unique structure and high fiber performance. In this review,the emergence of sponges,evolutionary novelties found in sponges,and the phylogenetic position of sponges in early metazoan evolution are highlighted. In ad-dition,the present state of knowledge on silicatein-mediated "biosilica" formation in marine sponges,including the involvement of other molecules in silica metabolism and their potential application in nanobiotechnology and medicine,is given. 相似文献