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101.
Summary After injection of microspheres into both renal arteries of rats, an irreversible shock syndrome develops, resulting in death within 4–12 h. Ligation of both renal pedicles after injection of microspheres prevents the shock. It is presumed that kininogenases released from the kidneys participate in the pathogenesis of the shock syndrome.These studies were supported in part by the Deutsche Forschungsgemeinschaft within the SFB 90, Cardiovasculäres System. 相似文献
102.
J. Kapitola H. Dlouhá Dr. J. Křeček J. Zicha 《Cellular and molecular life sciences : CMLS》1977,33(12):1615-1616
Summary Neurohypophyseal blood flow increases in water-deprived rats. This increase is independent of vasopressin release, since it occurs even in rats with hereditary defect of hypothalamic vasopressin synthesis.Acknowledgment. The technical assistance of D. Vilimovská is acknowledged. 相似文献
103.
H. -J. Hess J. S. Bindra J. W. Constantine W. Elger O. Loge E. Schillinger W. Losert 《Cellular and molecular life sciences : CMLS》1977,33(8):1076-1077
Summary N-methanesulfonyl 16-phenoxy--tetranor PGE2 is a prostaglandin analog which is markedly more tissue selective than PGE2. This compound is 10–30 times more potent than PGE2 in animal models which are considered relevant to antifertility effects in humans. In pharmacological tests which are believed to be predictive for side effects in humans, the compound has potency either equal to or less than that of PGE2. 相似文献
104.
105.
M. B. Castillo M. D. Gonzalez G. Burton C. P. Lantos A. Roldán 《Cellular and molecular life sciences : CMLS》1983,39(6):617-618
Summary A dissociation between inhibition of RNA synthesis and cell lysis was observed when thymocytes of adrenalectomized rats were incubated with high concentrations of pregn-4-ene-11-ol-3, 20-dione and pregna-1,4-diene-11-ol-3,20-dione. In contrast, no dissociation of these effects was found with the typical glucocorticoids cortisol and corticosterone, nor with their 1,4-diene analogs under the same conditions.Acknowledgments. This work was supported by grants from the Consejo Nacional de Investigaciones Científicas y Técnicas de la República Argentina to the Instituto de Biologia y Medicina Experimental and the Programa de Regulación Hormonal y Metabólica as well as by financial help from the Secretaría de Ciencia y Tecnología. 相似文献
106.
Summary Daily evening injections of isoproterenol extended the period of high pineal N-acetyltransferase activity and retarded the growth of testes, seminal vesicles and prostate in rats treated neonatally with testosterone propionate.The authors are grateful to Mrs Marie Svobodová for her skillful technical assistance. 相似文献
107.
G. D. Ledney H. M. Gelston Jr S. R. Weinberg E. D. Exum 《Cellular and molecular life sciences : CMLS》1982,38(10):1228-1230
Summary Wound trauma-induced survival from radiation may be related to increased mitosis in hematopoietic cells. This is supported by the cell cycle-dependent drug hydroxyurea, which 1. blocked survival of wounded mice injected 2 or 3 days after 900 rad and 2. reduced the number of endogenous CFU-s in wounded mice injected shortly before 700 rad.Supported by the Armed Forces Radiobiology Research Institute, Defense Nuclear Agency, under Research Work Unit MJ00018. Views presented in this paper are those of the authors; no endorsement by the Defense Nuclear Agency has been given or should be inferred.Research was conducted according to the principles enunciated in the Guide for the Care and Use of Laboratory Animals prepared by the Institute of Laboratory Research, National Research Council. 相似文献
108.
G. Zamboni E. Perez P. L. Parmeggiani 《Cellular and molecular life sciences : CMLS》1982,38(10):1188-1189
Summary In rats adapted to a 1212 h light-dark (LD) schedule, cyclic AMP concentration in the preoptic region showed a L minimum and D maximum. No significant fluctuations were observed in the parietal cortex.Supported by grant No. 79.01946.04 awarded by the National Research Council (CNR), Rome, Italy. 相似文献
109.
Captopril (SQ 14,225): In vitro and in vivo influence on the proliferative response of rat lymphocytes 总被引:1,自引:0,他引:1
Lise Binderup E. Bramm E. Arrigoni-Martelli 《Cellular and molecular life sciences : CMLS》1982,38(3):399-401
Summary Captopril in vitro (50–500 g/ml) increased3H-TdR incorporation in unstimulated and mitogen-stimulated cultures of rat lymphocytes. Unseparated spleen and lymph node cells of rats orally treated with captopril (50 mg/kg/day×4) showed decreased basal and mitogen stimulated3H-TdR incorporation. The removal of macrophages abrogated this inhibitory effect. Leucine aminopeptidase activity of macrophages was reduced — in vivo and in vitro — by captopril.Acknowledgments. The authors thank the Squibb Institute for Medical Research for the gift of Captopril. The excellent technical assistance of Ms B. Hasselriis, Ms B. Rumler and Ms E. Greve Petersen is gratefully acknowledged. 相似文献
110.
Summary The defense secretion of soldiers ofReticulitermes lucifugus has been shown to contain, predominantly, (R)-(–)-(E,E)-geranyllinalool together with germacrene A and -farnesene.This report covers part of a collaborative study with J.-L. Clément, Lab. d'Evolution, Université P. et M. Curie, Paris, to whom we are grateful for supplies of material and discussions. We also thank Dr O.T. Jones for collections ofReticulitermes lucifugus. 相似文献