An ERP study for the degrees of the difficulty in visual search

The present study mainly probed the relationships between ERP components and the degrees of difficulty in visual search. Three experimental and one controlled conditions were randomly selected. Results showed that the P1, N1, and P2 amplitudes and latencies had no significant differences among the three experimental and one controlled conditions, and the ERP waveforms of low perceptual load of visual search were different from that of high perceptual load. These results might indicate that the latencies and amplitudes of initial P1, N1 and P2 in high and low perceptual load conditions were almost the same. The ERP waveforms of parallel search were very different from that of serial search, and the ERP waveforms of serial search were very similar. The P3 amplitudes increased as the degrees of the difficulty in visual search decreased.     

谈谈多媒体英语教学

文章介绍综合利用软件，创造良好的多媒体英语教学环境的方法和多媒体在英语课堂上的使用，以及多媒体英语教学需要注意的问题。     

基于SQL的报表生成系统

本文介绍的报表生成系统的取数方式可用ＳＱＬ语句，使系统具有通用性，灵活性等特点。在系统实现中采用了多窗口全屏幕方式定义报表格式及取数方式。系统用户界面友好，直观、简单易学。     

近代中国科学技术落后的思考

中国曾经创造出遥遥领先于西方一千多年的灿烂的古代科学技术．但是，从１７、１８世纪以后，中国科学技术却开始滑坡，被此时取得高速发展的西方科学技术远远地抛到了后面．这一历史大换位，成为人们关注的问题．本文通过纵向和横向比较，综述了近代中国落后的史实，探析了落后的历史经济原因、政治原因和政策原因．警示今人记取史训，努力振兴中国现代科技     

Human cytomegalovirus UL97 open reading frame encodes a protein that phosphorylates the antiviral nucleoside analogue ganciclovir.

Human cytomegalovirus (HCMV, a betaherpes virus) is the cause of serious disease in immunologically compromised individuals, including those with acquired immunodeficiency syndrome. One of the compounds used in the chemotherapy of HCMV infections is the nucleoside analogue 9-(1,3-dihydroxy-2-propoxymethyl)-guanine (ganciclovir). The mechanism of action of this drug is dependent on the formation of the nucleoside triphosphate, which is a strong inhibitor of the viral DNA polymerase. Thymidine kinase, which is encoded by many of the herpesviruses, catalyses the initial phosphorylation of ganciclovir. But there is no evidence for the coding of this enzyme by HCMV, and DNA sequence analysis of the HCMV genome has shown that there is no open reading frame characteristic of a herpesvirus thymidine kinase. Here we present biochemical and immunological evidence that the HCMV UL97 open reading frame codes for a protein capable of phosphorylating ganciclovir. This protein seems to be responsible for the selectivity of ganciclovir and will be useful tool in the understanding and refinement of the antiviral activity of new selective anti-HCMV compounds.     

Effect of volatile anesthetics on the circular dichroism of bilirubin bound to human serum albumin

The characteristic circular dichroism of bilirubin bound to human serum albumin undergoes a remarkable sign inversion on addition of halothane, chloroform and other volatile anesthetics. This sign inversion, which is completely reversed by removal of the anesthetic, reflects a pronounced conformational change of the bound ligand; probably a complete inversion of chirality. The observation suggests that association of volatile anesthetics with proteins can markedly alter the internal topography of receptor sites and potentially influence the stereoselectivity of ligand binding.     

几个求和公式的推导

本文利用差分的方法，推导出几个常见的求和公式。