线性与非线性有限单元分析概论计算方法

本书是关于线性和非线性有限单元法的入门教材，是根据作者在过去12年里为美国新奥尔良大学的多个专业学生讲授这两门课程的基础上逐步编撰而成。本书不同于已有教材，有许多新颖的特点，如重视基础应用，力求最少涉及数学理论；内容涉及的专业范围宽，选用大量不同专业的问题进行引导，可供多种学科背景的学生学习；在讲述理论的同时将相关软件的使用贯穿全书。     

下一代传输网络：传输、管理和控制位面

本书全面论述了传输、管理和控制位面的技术，介绍了一些有用的、现行的和下一代电讯网络技术的参考信息。四位作者均在电信学研究、产品开发等方面具有20年以上的经验。     

哲学性的科学家伟大科学发现之哲学结果

这是一本关于哲学如何给物理带来灵感，而物理又如何去影响哲学的书。哲学给科学带来基本观念和预设，但通过科学发现，这些观念又常常受到怀疑和修正，而伟大的科学家常常知道这种影响的脉络所在。本书通过清晰的论述和精美的插图，以科学哲人为中心讲述了他们的伟大发现，以及什么力量又促使他们重新考虑那些过去科学描述自然世界的惯常观念。书中还阐述了：因为电磁学、热力学和原子结构上的发现，使我们对科学和自然的理解经历了基本概念上的改变。     

The effects of manganese and barium on the cardiac pacemaker current,i f,in rabbit sino-atrial node myocytes

Summary The isolation of ionic fluxes contributing to electric currents through cell membranes often requires block of other undesired components which can be achieved, among others, by divalent cations. Mn²⁺ and Ba²⁺ are often used, for example, to block Ca and K currents. Here we have investigated the effects of these two cations on the properties of the hyperpolarization-activated pacemaker current i_f, in rabbit sino-atrial node myocytes, as obtained by voltage clamp analysis. We find that 2 mM Mn²⁺ shifts the i_f activation curve by 3.2±0.3 mV towards more positive values. However, when 1 mM Ba²⁺ is also added, the positive shift is more than halved (1.3±0.2 mV). We find, too, that in the absence of blocking cations the ACh-induced i_f inhibition is slightly higher than in their presence. These results indicate that the alteration of i_f kinetic properties by Ba²⁺ plus Mn²⁺-containing solutions is minimal.     

Heterochromatin characterization and distribution in the chromosomes of two populations ofIdotea baltica basteri Audouin, 1826 (Isopoda,Valvifera)

Two mediterranean populations ofIdotea baltica basteri from Messina and Naples showed a set of chromosomes composed by 58 all-biarmed chromosomes. The heterochromatin was located in the pericentromeric region of the chromosomes, and its composition appeared heterogeneous. In fact, not all the homologs showed heterochromatin resistant to digestion with three restriction enzymes (Alu I, Hae III and Sau 3A). Moreover, the two populations showed polymorphism in a band of G+C-rich telomeric heterochromatin, which was present only in the population from Messina. It is hypothesized that chromosomal polymorphism might reflect the geographical isolation of the two populations. It is also suggested that a process of diversification is taking place.     

Neuronal cell-cell adhesion depends on interactions of N-CAM with heparin-like molecules

Cell-cell interactions are of critical importance during neural development, particularly since the migration of neural cells and the establishment of functional interactions between growing axons and their target cells has been suggested to depend upon cell recognition processes. Neurone-neurone adhesion has been well studied in vitro, and is mediated in part by the neural cell adhesion molecule N-CAM. N-CAM-mediated cell-cell adhesion has been postulated to occur by a homophilic binding mechanism, in which N-CAM on the surface of one cell binds to N-CAM on a neighbouring cell. Studies in our laboratory have identified a cell surface glycoprotein, now known to be N-CAM, which participates in cell-substratum interactions in the developing chicken nervous system. Although this adhesion involves a homophilic binding mechanism, the binding of the cell surface proteoglycan heparan sulphate to the glycoprotein is also required. This raises the question of whether the binding of heparan sulphate to N-CAM is also required for cell-cell adhesion. Here we show that the binding of retinal probe cells to retinal cell monolayers is inhibited by heparin, a functional analogue of heparan sulphate, but not by chondroitin sulphate. Monoclonal antibodies that recognize two different domains on N-CAM, the homophilic-binding and heparin-binding domains, inhibit cell-cell adhesion. The heparin-binding domain isolated from N-CAM by selective proteolysis also inhibits cell-cell adhesion when bound to the probe cells.