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11.
飞龙掌血水提物的扩血管作用及原理初探 总被引:6,自引:4,他引:6
任先达 《暨南大学学报(自然科学与医学版)》1990,11(2):29-35
飞龙掌血的水提物飞龙一号(F01)给小鼠腹腔注射,其 LD_(50)=3.70g/kg。F01(80mg/kg)对麻醉 S.D.大鼠有明显降血压作用,伴有心率加快。该作用无快速耐受性,且不被 H_1及 H_2组胺受体、M 胆碱受体及β肾上腺素受体之阻断剂取消。对于离体 S.D.大鼠尾动脉螺旋条,F01(0.3至3mg/ml)可使由 KCl(60mmol/L)、NE(0.1μmol/L)或 AVP(0.01μmol/L)刺激而收缩的组织明显舒张。KCI(80mmol/L)增加血管平滑肌组织对钙的撮取,这可以通过测定组织中未被镧置换的低亲和力同位素~(45)Ca 的含量来确定。F01(0.06至4mg/ml)可显著降低这种钙摄取的增加。上述结果表明,F01具有直接扩张血管作用,此种作用与抑制钙内流有关。 相似文献
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胡坚达 《浙江万里学院学报》2002,15(2):85-87
随着高等教育收费制度改革力度的加大,家庭经济困难的学生化比例日增,特别是在浙江省的民办二级学院中,这一现象更为明显。国家助学贷款政策的出台,有效地解决了部分经济困难家庭孩子上大学的问题。但由于宁波科技学院2001年才实施这项利国利民的政策,并且在实际实施过程中有一定难度。为此文章针对民办二级学院中实施国家助学贷款的现状进行了分析研究,提出了相应对策,力求把助学贷款工作做得更好。 相似文献
13.
为提高存储系统的可用性 ,在 Windows2 0 0 0系统中实现了SCSI冗余路径驱动程序 RDP。在路径发生故障时由 RDP将 I/ O切换到其他路径。通过将 I/ O负载均衡分布在各 SCSI路径 ,能增加系统 I/ O处理能力 相似文献
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Viable metacyclic forms of T. cruzi, Y strain, treated with an adequate dose of actinomycin D (50 micrograms Act-D/ml/10(7) parasites/ml for 72 h at 28 degrees C) showed the following properties: 1) they lost their ability to replicate in culture medium, in blood and in tissues of normal mice and were no longer able to incorporate tritiated thymidine; 2) they could not penetrate into Vero cells and could not replicate inside normal macrophages; 3) they retained their immunogenicity and the ability to protect mice against a virulent infection; 4) they did not induce histological lesions as described in chronic experimental Chagas' disease. 相似文献
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Crystallization of a second adenovirus protein (the fibre) 总被引:5,自引:0,他引:5
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Hummingbirds have developed a wealth of intriguing features, such as backwards flight, ultraviolet vision, extremely high metabolic rates, nocturnal hibernation, high brain-to-body size ratio and a remarkable species-specific diversity of vocalizations. Like humans, they have also developed the rare trait of vocal learning, this being the ability to acquire vocalizations through imitation rather than instinct. Here we show, using behaviourally driven gene expression in freely ranging tropical animals, that the forebrain of hummingbirds contains seven discrete structures that are active during singing, providing the first anatomical and functional demonstration of vocal nuclei in hummingbirds. These structures are strikingly similar to seven forebrain regions that are involved in vocal learning and production in songbirds and parrots--the only other avian orders known to be vocal learners. This similarity is surprising, as songbirds, parrots and hummingbirds are thought to have evolved vocal learning and associated brain structures independently, and it indicates that strong constraints may influence the evolution of forebrain vocal nuclei. 相似文献
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Accurate modelling of volatility (or risk) is important in finance, particularly as it relates to the modelling and forecasting of value‐at‐risk (VaR) thresholds. As financial applications typically deal with a portfolio of assets and risk, there are several multivariate GARCH models which specify the risk of one asset as depending on its own past as well as the past behaviour of other assets. Multivariate effects, whereby the risk of a given asset depends on the previous risk of any other asset, are termed spillover effects. In this paper we analyse the importance of considering spillover effects when forecasting financial volatility. The forecasting performance of the VARMA‐GARCH model of Ling and McAleer (2003), which includes spillover effects from all assets, the CCC model of Bollerslev (1990), which includes no spillovers, and a new Portfolio Spillover GARCH (PS‐GARCH) model, which accommodates aggregate spillovers parsimoniously and hence avoids the so‐called curse of dimensionality, are compared using a VaR example for a portfolio containing four international stock market indices. The empirical results suggest that spillover effects are statistically significant. However, the VaR threshold forecasts are generally found to be insensitive to the inclusion of spillover effects in any of the multivariate models considered. Copyright © 2008 John Wiley & Sons, Ltd. 相似文献