灯盏乙素对大鼠肝线粒体氧化损伤的抑制作用

运用Fe^2 -Vc损伤体系诱导大鼠肝线粒体氧化损伤，并研究了灯盏乙素的抑制作用，采用分光光度法测定脂质过氧化物丙二醛（MDA）含量，膜蛋白巯基含量及线粒体肿胀度，利用荧光染料Rhodamine123对线粒体进行标记，跟踪线粒体膜电位的变化，研究发现20－50μmol/L的灯盏乙素能抑制MDA的生成并促使膜巯基含量下降，对线粒体肿胀和膜电位的降低都有一定的抑制作用，并呈剂量依赖关系，结果表明灯盏乙素是一种有效的抗氧化剂，能抑制活性氧诱导的线粒体氧化损伤。μ     

基于H263/TMN8的前后景码率分配及控制

在H263ZI‘MN8的控制技术基础上,提出可控的前后景码率分配算法、前景区优先编码策略以及优化的量化编码次序．可以仅使用一个控制参数来控制前后景的码率分配,并且编码后码流仍符合标准I-t263码流．试验结果表明,该算法在低比特率的情况下视频图像的主观质量要优于TMN8,非常适合窄信道视频通信的应用．     

油藏数值模拟在剩余油预测中的不确定性分析

油藏数值模拟作为一种定量的剩余油饱和度预测方法 ,在油田开发后期剩余油分布研究中起着越来越重要的作用 ,但其预测精度也不可避免地受到多种因素的影响。对剩余油预测中油藏数值模拟精度的影响因素进行了分析 ,结果表明 ,地层对比的多解性、储层物性参数求取的不确定性以及储层非均质描述的局限性是影响数值模拟精度的主要地质因素。此外 ,相对渗透率曲线的选取、动态数据的获取及数值模拟软件本身都存在较大的不确定性 ,这些都会影响到油藏数值模拟的精度。因此 ,在剩余油研究过程中 ,不能过分依赖油藏数值模拟。应该综合运用地质、地震、测井、油藏工程、油藏数值模拟等多学科知识进行研究 ,以提高剩余油饱和度的预测精度。     

基于图像信息处理的车辆自动驾驶控制方法

在分析驾驶员利用图像信息进行驾驶的一般规律基础上,提出了利用图像信息处理技术实现车辆路迹追踪自动行驶的控制方法和规则,并进行了模拟计算和试验．结果表明,所提出的控制方法和规则用于进行车辆的自动驾驶是可行的．     

用具有零权的平差方法求解秩亏自由网的研究

以秩亏自由网平差的法方程系数阵的特征根作为虚拟权 ,构造两组虚拟误差方程 ,其中一组具有零权 ,从而用具有零权的平差思想 ,导出求解秩亏自由网待估参数平差值及其协因数的公式 ,并指出 ,此结果与用主成分估计法求解秩亏自由网的结果完全一致。     

基于遗传算法的模糊聚类方法

针对模糊c 均值算法容易收敛于局部极小点的缺陷 ,将遗传算法应用于模糊c 均值算法的优化计算中 .算法采用实数编码 ,提高了试验精度 .实验证明基于遗传算法的模糊聚类方法能够在一定程度上克服初值的影响 ,跳出局部极小点 ,在大样本的聚类方面有较大的优势 .     

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease.

A locus segregating with familial Alzheimer's disease (AD) has been mapped to chromosome 21, close to the amyloid precursor protein (APP) gene. Recombinants between the APP gene and the AD locus have been reported which seemed to exclude it as the site of the mutation causing familial AD. But recent genetic analysis of a large number of AD families has demonstrated that the disease is heterogeneous. Families with late-onset AD do not show linkage to chromosome 21 markers. Some families with early-onset AD show linkage to chromosome 21 markers, but some do not. This has led to the suggestion that there is non-allelic genetic heterogeneity even within early onset familial AD. To avoid the problems that heterogeneity poses for genetic analysis, we have examined the cosegregation of AD and markers along the long arm of chromosome 21 in a single family with AD confirmed by autopsy. Here we demonstrate that in this kindred, which shows linkage to chromosome 21 markers, there is a point mutation in the APP gene. This mutation causes an amino-acid substitution (Val----Ile) close to the carboxy terminus of the beta-amyloid peptide. Screening other cases of familial AD revealed a second unrelated family in which this variant occurs. This suggests that some cases of AD could be caused by mutations in the APP gene.     

幂律流体管内充分发展的对流换热分析

将非牛顿流体的动量方程、能量方程和幂律流体的本构方程相结合 ,建立了幂律流体管内流动和换热充分发展时的对流换热控制方程组 ,并在恒热流和恒壁温边界条件下分别对方程组进行了求解 ,得到了两种不同边界条件下的温度分布和无量纲对流换热系数 (Nu数 )的表达式。结果表明 ,幂律流体的流变指数对流体流动的影响要大于对换热的影响 ;在恒热流边界条件下 ,幂律流体的温度在管内沿轴向呈线性分布 ;而在恒壁温条件下 ,其截面平均温度沿轴向呈指数规律变化。幂律流体的无量纲对流换热系数与幂律流体的流变指数有关 ,并且在两种边界条件下 ,均随着流变指数的增加而减小     

'Designer atoms' for quantum metrology

Entanglement is recognized as a key resource for quantum computation and quantum cryptography. For quantum metrology, the use of entangled states has been discussed and demonstrated as a means of improving the signal-to-noise ratio. In addition, entangled states have been used in experiments for efficient quantum state detection and for the measurement of scattering lengths. In quantum information processing, manipulation of individual quantum bits allows for the tailored design of specific states that are insensitive to the detrimental influences of an environment. Such 'decoherence-free subspaces' (ref. 10) protect quantum information and yield significantly enhanced coherence times. Here we use a decoherence-free subspace with specifically designed entangled states to demonstrate precision spectroscopy of a pair of trapped Ca+ ions; we obtain the electric quadrupole moment, which is of use for frequency standard applications. We find that entangled states are not only useful for enhancing the signal-to-noise ratio in frequency measurements--a suitably designed pair of atoms also allows clock measurements in the presence of strong technical noise. Our technique makes explicit use of non-locality as an entanglement property and provides an approach for 'designed' quantum metrology.     

复合材料层压板疲劳寿命预测方法

测定了碳纤维／树脂基T300／QY8911复合材料的3组典型单轴循环应力下的S-N曲线．基于试验数据，建立了多轴循环应力作用下单向板的寿命模型，并通过整合平面应力分析、失效分析和材料性质退化模块模拟多向层压板的疲劳失效过程．这种方法试图基于单向板在确定应力比下的疲劳试验结果，预测同种材料体系的任意铺层形式的多向层压板在复杂循环应力作用下的疲劳寿命．对于以分层破坏为主控因素的层压板，基于层间应力的计算结果，用计算面内累计损伤的方法计算分层损伤，层压板的寿命等于分层扩展寿命和分层后子层板剩余寿命之和．考虑分层扩展后，层压板的寿命预测结果得到明显改善．