Mechanisms of heterotypic immunity against canine distemper.

Hep-2 cells infected with measles virus (MV) for as short as 6 h became refractory to superinfection with canine distemper virus (CDV) but not to vesicular stomatitis virus (VSV). The exact mechanism of such interference is unknown but probably occurs after virus attachment and penetration. These results verify the suggestion that virus interference may be a mechanism of heterotypic protection against canine distemper.     

Amphiphilic spectroscopic probes utilizing metal chelates.

The synthesis and initial applications are reported for 1-[p-(palmitamido)-phenyl]ethylenedinitrilotetraacetic acid. The results demonstrate the versatility of this spectroscopic probe molecule, which allows choice of a particular technique for a particular system as well as use of multiple spectroscopic techniques for complementary information about hydrophobic regions in biological systems.     

Octopamine levels during the moult cycle and adult development in the migratory locust, Locusta migratoria.

Octopamine content of the head of the locust Locusta migratoria has been determined during the last larval stage, moulting and adult life of 3 groups of insects: female and male gregarious, solitary and CO2 solitarized. An important difference was found between these 3 groups. Octopamine contents increased in the middle of the larval life and during the adult life. The moulting time is characterized by a sharp decrease of the octopamine content which becomes identical in the 3 groups of insects. The relation between octopamine content, hormone cycles and motility is discussed.     

Myosin-like protein in the human parathyroid glands: an immunohistochemical study.

The immunofluorescent staining of the human parathyroid glands shows that the principal cells bind antimyosin-like antibodies. The presence of a myosin-like protein in the principal cells of the human parathyroid glands is presumably in rapport with parathormone secretion.     

Relationship between the pentose phosphate shunt and methemoglobin reductase activity in human erythrocytes: Effect of aging on methemoglobin reductase activity.

The increase in methemoglobin reductase activity in human erythrocytes upon incubation with inosine, phosphate, pyruvate occurs only in the presence of methylene blue. No difference in activity of the methemoglobin reductases was observed between enzyme extracts of fresh cells and aged cells.     

Age variation in the increase of hypothalamic and brain stem contents of phenylethanolamine m-octopamine and p-octopamine in spontaneously hypertensive rats (SH Kyoto).

Phenylethanolamine, m-octopamine and p-octopamine contents were determined as a function of age in the hypothalamus and brain stem of spontaneously hypertensive rats and controls Wistar Kyoto. In hypothalamus, the content of the 3 amines was 2--4-fold greater for the SH rats. In the brain stem, the phenylethanolamine and p-octopamine contents were 2--3-fold greater in SH rats but 5--6-fold higher in the case of m-octopamine. The difference appears at 3 weeks and correlates the blood pressure with the increase of age. The significance of these findings is discussed.     

The effect of age on cardiac output and its distribution in the rat.

Cardiac output distribution in the rat was found to be affected by age. Cardiac index and blood flow to the liver, kidneys, skin and skeletal muscle were lower in 11-12 month compared to 3-4 month old rats.     

Cathétérisme intracardiaque en clinique

Summary Cardiac catheterization, initially conducted byForssmann in 1929, has become a qualified clinical method. A fine rubber catheter is introduced into the antecubital vein and mechanically reaches the right heart chambers; auricular and ventricular, as well as the pulmonary artery. In some exceptional cases the left auricle and ventricle likewise lend themselves to exploration.     

Fettsäuren aus dehydratisiertem Rizinusöl mit sog. Vitamin-F-Wirkung

Summary The fatty acids from dehydrated castor oil, mainly consisting of 9,11- and 9,12-linoleic acid, show in biological tests vitamin effects similar to those of the so-called essential fatty acids.     

Un curare d'une Erythrine africaine

Summary An alcaloid C₁₆H₁₉NO₃ has been isolated fromErythrina tholloniana; the iodohydrate of this erythroidine has a melting point of 225°C and 239°C for its chlorhydrate. It has a powerful curare-like action on the frog or on its isolated sciatic-sartorius preparation; at a concentration of less than 1/1,000,000, a complete neuromuscular block is produced: the electrical stimulation of the motor nerve does not produce any contraction, but the muscle reacts by an end-plate potential having the same characteristics (shape, duration, possibility of summation) as the electrical waves produced in the same preparation curarized by ordinary curare or by quaternary ammonium derivatives. Decurarization by veratrine 1/200,000 is accompanied by the same electrical reactions as those which have been described in preparations treated by curare.On mammals, the alcaloid has little curariform activity; on the isolated phrenic-diaphragm preparation of the rat, incomplete block was produced at a concentration of 1/5000.