Aneuploidy of glandular epithelial cells in histologically normal prostate glands

Summary The percentage of aneuploidy in normal prostate glands from subjects 13–38 years old and 45–66 years old ranged from 0–78% and 0–63%, respectively. In contrast to adults, aneuploidy was absent in fetal and postnatal prostates. It is concluded that aneuploidy is a fundamental attribute of histologically normal adult prostate glands.     

The re-emergence of the GP73 and fucosylated liver cancer biomarkers

The study shows that GP73 alone may not be sufficient to achieve the discrimination in every population. This is because many other clinical factors may influence the levels of the biomarker. This review attempts to identify some of these clinical variables, and helps provide a means of using these clinical values, in combi- nation with GP73, to achieve the best use of the entire clinical biomarker family.