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91.
Zusammenfassung Die Stereospezifität der Enzyme des Allantoinabbaus inStreptococcus allantoicus und die optische Drehung der Reaktionsprodukte wurde bestimmt. Allantoinase war aspezifisch, während Allantoate-amidohydrolase ausschliesslich (-)-Ureidoglykolate bildete. Diese Substanz wurde durch (-)-Ureidoglykolase hydrolysiert. 相似文献
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93.
Dr. D. Keslev S. Van Puymbroeck O. Van der Borght 《Cellular and molecular life sciences : CMLS》1972,28(5):524-525
Résumé L'administration presque simultanée d'un gel de phosphate d'alumine et de226RaCl2 réduit de 800 fois l'absorption intestinale du226Ra chez la souris. La charge corporelle en85Sr et47Ca est réduite d'environ 10 resp. 3 fois. 相似文献
94.
N. Radoiu P. L. Wolf F. A. Zydeck E. T. Konno Janice Vazquez Elisabeth Von der Muehll 《Cellular and molecular life sciences : CMLS》1968,24(7):719-721
Zusammenfassung Dank einer neuen Anwendung von Lymphknotenextrakten (statt Röntgenextrakten, Corticosteroiden, Antilymphozytenserum usw.) wird eine erhebliche Reduktion der immunologischen Reaktion erzielt, wenn die Tiere mit diesen Extrakten vorbehandelt und gleichzeitig mit Antigenen behandelt werden.
This investigation was supported in part by U.S.P.H.S. Research Grant No. CA-02624 from National Cancer Institute; and in part by an institutional grant to Detroit Institute of Cancer Research from United Foundation of greater Detroit allocated through Michigan Cancer Foundation and the Detroit General Hospital Research Corporation, and Newaygo County Cancer Society. 相似文献
This investigation was supported in part by U.S.P.H.S. Research Grant No. CA-02624 from National Cancer Institute; and in part by an institutional grant to Detroit Institute of Cancer Research from United Foundation of greater Detroit allocated through Michigan Cancer Foundation and the Detroit General Hospital Research Corporation, and Newaygo County Cancer Society. 相似文献
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96.
Suh GS Wong AM Hergarden AC Wang JW Simon AF Benzer S Axel R Anderson DJ 《Nature》2004,431(7010):854-859
All animals exhibit innate behaviours in response to specific sensory stimuli that are likely to result from the activation of developmentally programmed neural circuits. Here we observe that Drosophila exhibit robust avoidance to odours released by stressed flies. Gas chromatography and mass spectrometry identifies one component of this 'Drosophila stress odorant (dSO)' as CO2. CO2 elicits avoidance behaviour, at levels as low as 0.1%. We used two-photon imaging with the Ca2+-sensitive fluorescent protein G-CaMP to map the primary sensory neurons governing avoidance to CO2. CO2 activates only a single glomerulus in the antennal lobe, the V glomerulus; moreover, this glomerulus is not activated by any of 26 other odorants tested. Inhibition of synaptic transmission in sensory neurons that innervate the V glomerulus, using a temperature-sensitive Shibire gene (Shi(ts)), blocks the avoidance response to CO2. Inhibition of synaptic release in the vast majority of other olfactory receptor neurons has no effect on this behaviour. These data demonstrate that the activation of a single population of sensory neurons innervating one glomerulus is responsible for an innate avoidance behaviour in Drosophila. 相似文献
97.
Sand can normally support a weight by relying on internal force chains. Here we weaken this force-chain structure in very fine sand by allowing air to flow through it: we find that the sand can then no longer support weight, even when the air is turned off and the bed has settled--a ball sinks into the sand to a depth of about five diameters. The final depth of the ball scales linearly with its mass and, above a threshold mass, a jet is formed that shoots sand violently into the air. 相似文献
98.
van Boekel R Min M Leinert Ch Waters LB Richichi A Chesneau O Dominik C Jaffe W Dutrey A Graser U Henning T de Jong J Köhler R de Koter A Lopez B Malbet F Morel S Paresce F Perrin G Preibisch T Przygodda F Schöller M Wittkowski M 《Nature》2004,432(7016):479-482
Our Solar System was formed from a cloud of gas and dust. Most of the dust mass is contained in amorphous silicates, yet crystalline silicates are abundant throughout the Solar System, reflecting the thermal and chemical alteration of solids during planet formation. (Even primitive bodies such as comets contain crystalline silicates.) Little is known about the evolution of the dust that forms Earth-like planets. Here we report spatially resolved detections and compositional analyses of these building blocks in the innermost two astronomical units of three proto-planetary disks. We find the dust in these regions to be highly crystallized, more so than any other dust observed in young stars until now. In addition, the outer region of one star has equal amounts of pyroxene and olivine, whereas the inner regions are dominated by olivine. The spectral shape of the inner-disk spectra shows surprising similarity with Solar System comets. Radial-mixing models naturally explain this resemblance as well as the gradient in chemical composition. Our observations imply that silicates crystallize before any terrestrial planets are formed, consistent with the composition of meteorites in the Solar System. 相似文献
99.
100.
Earl PL Americo JL Wyatt LS Eller LA Whitbeck JC Cohen GH Eisenberg RJ Hartmann CJ Jackson DL Kulesh DA Martinez MJ Miller DM Mucker EM Shamblin JD Zwiers SH Huggins JW Jahrling PB Moss B 《Nature》2004,428(6979):182-185
The potential use of smallpox as a biological weapon has led to the production and stockpiling of smallpox vaccine and the immunization of some healthcare workers. Another public health goal is the licensing of a safer vaccine that could benefit the millions of people advised not to take the current one because they or their contacts have increased susceptibility to severe vaccine side effects. As vaccines can no longer be tested for their ability to prevent smallpox, licensing will necessarily include comparative immunogenicity and protection studies in non-human primates. Here we compare the highly attenuated modified vaccinia virus Ankara (MVA) with the licensed Dryvax vaccine in a monkey model. After two doses of MVA or one dose of MVA followed by Dryvax, antibody binding and neutralizing titres and T-cell responses were equivalent or higher than those induced by Dryvax alone. After challenge with monkeypox virus, unimmunized animals developed more than 500 pustular skin lesions and became gravely ill or died, whereas vaccinated animals were healthy and asymptomatic, except for a small number of transient skin lesions in animals immunized only with MVA. 相似文献