Thermoregulatory heat production by periaortic brown adipose tissue in the non-cold-acclima. tized rat

Zusammenfassung Mit Thermoelementen im Aortenbogen und 35 mm distal davon gemessener Temperatur zeigt sich in thermoneutraler Umgebung entweder keine oder nur eine geringere Temperaturerhöhung des distalen Punktes. In kalter Umgebung hingegen ist die Differenz signifikant vergrössert.     

Stimulation of the growth of murine bone marrow colonies in vitro by an acute inflammatory exudate. Comparison with colony stimulating factor CSF)]

Formation of colonies from mice bone marrow progenitors of macrophages and granulocytes in methylcellulose culture was induced by an inflammatory pleural exudate obtained from mice injected with dextran. Mitogenic activity of this acute inflammatory exudate was compared with that of colony stimulating factor (CSF). It was found that colony and cluster counts, during 10 days of culture, were similar with the two types of stimulating factors. When used at the same dose, exudate was less active than CSF. It was concluded that inflammatory exudate showed an activity similar to that of CSF but contained a smaller amount of stimulating factor. Further cytochemical studies are necessary to specify whether or not the two factors induced the same type of colonies (monocytic or granulocytic).     

Oncostatic activity of extracts from Alangium vitiense on murine lymphoid neoplasms]

A total alkaloid and two purified alkaloid extracts of Alangium Vitiense were revealed by our experimental screening to be oncostatic on L1210 leukemia and two other lymphoid neoplasias in Mice. They are not active on myelomonocytoid leukemia WEHI3 nor on B16 melanoma.     

Effects of bilateral lesions of the nuclei habenulae on plasma thyroxine levels in Japanese quail

Summary Electrolytic bilateral lesions of the nuclei habenulae were made in male, adult photostimulated quail. Habenular destruction led to a marked decrease in the plasma thyroxine level (40%), whereas sham operated birds did not differ from controls. This result appears to be somewhat different from those obtained in mammals and the mechanisms of habenular-thyroid interrelationships are unknown.     

Light and electron microscopic evidence of hypothalamic afferences originating from the hippocampus in the pigeon

Summary Degenerating nervous fibres and synaptic boutons were demonstrated in the nuclei posterior medialis hypothalami after hippocampal lesions in the pigeon (light and electron microscopy).Acknowledgments. The authors are indebted to Mr.Louis Dongan for histological assistance. Parts of this experiment were supported by a grant from the C. N. R. S. (ERA No. 85).     

Incorporation of H3-progesterone activity into 18-OH-corticosterone and 18-OH-11-desoxycorticosterone,aldosterone and corticosterone following treatment of formaldehyde and hydrocortisone,in pregnant and new-born rats and immediatelypost partum

Zusammenfassung Der Einbau von H³-Progesteron-Radioaktivität in verschiedenen Corticosteroiden wurde bei mit Formalin und Hydrocortison behandelten, trächtigen und neugeborenen Ratten mit Hilfe vonin vitro überlebenden Nebennierenschnittenpost partum untersucht. Die 18-OH-Corticosteronaktivität steigt nach Formalinbehandlung an; die Aktivitätpost partum gebildeter Corticosteroide vermindert sich im allgemeinen; bei neugeborenen Ratten ist die Aktivität des Corticosterons vermindert.     

The CO2-binding capacity of rat brain tissuein vivo

Zusammenfassung 73 Ratten wurden hyperventiliert und mit Gasgemischen verschiedener CO₂-Gehalte (0–12%) während 30–180 min beatmet (arteriellerP _{CO 2} 12–107 Torr). Die Versuchstiere wurdenin situ eingefroren und der CO₂-Gehalt des Gehirngewebes mit eigener Methode bestimmt. Dissoziationskurve und Pufferkapazität des Gehirngewebes für CO₂ in vivo werden mitgeteilt.