由电流环实现的多机通信系统

为解决恶劣环境下的远距离通信问题,本文设计了由电流环实现的多机通信系统,实践表明,该系统运行可靠,传输距离远,抗干扰能力强。     

一种电流模式有源滤波器的设计方法

论述了电流模式二阶有源滤波器的信号流图设计方法，给出了OTA－C型二阶节电路。不必改变电路结构即可以同时在三个输出端实现高通、带通、低通滤波功能。给出了计算机仿真结果。     

块状纳米材料的设计理论研究

在二元共晶Spinodal系统中 ,Spinodal波长的大小随过冷度的增加而减少 ,并存在一个最小的波长 ,此时合金的生长速度最快 .提出当过冷度足够大时 ,液态Spinodal的波长进入到纳米尺度 ,形成块状纳米材料 .由于液态的扩散较易发生 ,当波长为纳米量级时 ,Spinodal的转变时间为微秒量级 .由于液体表面张力等的影响 ,液态Spinodal的组织由网状变成微粒形态 .     

胆总管探查切口的Ⅰ期缝合

目的 :分析胆囊切除术胆总管探查阴性病例的处理方法。方法 :回顾性分析 5 5 2例良性病胆囊切除术连续病例。结果 :胆总管探查 380例中 15 1例探查阴性 ,其中 31例胆总管 期缝合 ,12 0例置 T管引流。结论 :胆总管探查阴性病例在术中胆道镜仔细检查的条件下 ,胆总管探查切口 期缝合是安全的。     

磁头定位系统温度特性的仿真研究

用计算机仿真研究磁头定位系统的性能随温度变化的特性，与测试分析相结合，得出了有关宽温带高精度磁头定位系统设计的一些有意义的结论．     

Angiotensin-converting enzyme 2 is an essential regulator of heart function

Cardiovascular diseases are predicted to be the most common cause of death worldwide by 2020. Here we show that angiotensin-converting enzyme 2 (ace2) maps to a defined quantitative trait locus (QTL) on the X chromosome in three different rat models of hypertension. In all hypertensive rat strains, ACE2 messenger RNA and protein expression were markedly reduced, suggesting that ace2 is a candidate gene for this QTL. Targeted disruption of ACE2 in mice results in a severe cardiac contractility defect, increased angiotensin II levels, and upregulation of hypoxia-induced genes in the heart. Genetic ablation of ACE on an ACE2 mutant background completely rescues the cardiac phenotype. But disruption of ACER, a Drosophila ACE2 homologue, results in a severe defect of heart morphogenesis. These genetic data for ACE2 show that it is an essential regulator of heart function in vivo.     

四生散对肺癌细胞增殖的抑制作用及毒性研究

主要探讨中药制剂四生散对人肺癌A5 4 9细胞株的增殖抑制作用以及其急性毒性.应用改进的MTT法测定四生散对肺癌细胞增殖的影响;采用琼脂糖凝胶电泳测定四生散对诱导肿瘤细胞凋亡的影响;再用分剂量组灌胃小鼠的方法,鉴定四生散的急性毒性.实验结果表明,四生散对人肺癌A5 4 9细胞株的增殖有较强的抑制作用,并具有明显的量效和时效相关性;经四生散处理后的A5 4 9细胞呈现凋亡特征性电泳条带;在3 2倍于人的剂量时,小鼠饮食和体重均在正常水平,并无异常,证实口服四生散无急性毒性.     

T形线散射电流的麦克斯韦电路

运用最新提出的麦克斯韦电路理论,分析T形线的散射电流,将该结构等效为LC电路,求解与之对应的微分方程,得到该结构的散射电流,数值实验分别计算了T形线的等效电路参数L,C,α,β,以及相应的散射电流,分析结果表明,所得电路参数和散射电流符合物理现象,并且与矩量法的结果以及相关文献中的结果均吻合,从而证明了该方法的正确性和...     

Human gamma-chain genes are rearranged in leukaemic T cells and map to the short arm of chromosome 7

Three gene families that rearrange during the somatic development of T cells have been identified in the murine genome. Two of these gene families (alpha and beta) encode subunits of the antigen-specific T-cell receptor and are also present in the human genome. The third gene family, designated here as the gamma-chain gene family, is rearranged in murine cytolytic T cells but not in most helper T cells. Here we present evidence that the human genome also contains gamma-chain genes that undergo somatic rearrangement in leukaemia-derived T cells. Murine gamma-chain genes appear to be encoded in gene segments that are analogous to the immunoglobulin gene variable, constant and joining segments. There are two closely related constant-region gene segments in the human genome. One of the constant-region genes is deleted in all three T-cell leukaemias that we have studied. The two constant-region gamma-chain genes reside on the short arm of chromosome 7 (7p15); this region is involved in chromosomal rearrangements identified in T cells from individuals with the immunodeficiency syndrome ataxia telangiectasia and observed only rarely in routine cytogenetic analyses of normal individuals. This region is also a secondary site of beta-chain gene hybridization.     

Bone marrow cells regenerate infarcted myocardium

Myocardial infarction leads to loss of tissue and impairment of cardiac performance. The remaining myocytes are unable to reconstitute the necrotic tissue, and the post-infarcted heart deteriorates with time. Injury to a target organ is sensed by distant stem cells, which migrate to the site of damage and undergo alternate stem cell differentiation; these events promote structural and functional repair. This high degree of stem cell plasticity prompted us to test whether dead myocardium could be restored by transplanting bone marrow cells in infarcted mice. We sorted lineage-negative (Lin-) bone marrow cells from transgenic mice expressing enhanced green fluorescent protein by fluorescence-activated cell sorting on the basis of c-kit expression. Shortly after coronary ligation, Lin- c-kitPOS cells were injected in the contracting wall bordering the infarct. Here we report that newly formed myocardium occupied 68% of the infarcted portion of the ventricle 9 days after transplanting the bone marrow cells. The developing tissue comprised proliferating myocytes and vascular structures. Our studies indicate that locally delivered bone marrow cells can generate de novo myocardium, ameliorating the outcome of coronary artery disease.