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991.
原油中的水滴在高压直流电场中被电场力分散成小液滴。通过测定小液滴的平均粒径和原油中被分散的水量,发现水滴的电分散程度与温度和电场强度的变化有密切关系。温度改变原油性质来影响水滴的变形断裂,其中粘性阻力起主导作用。电场强度会明显影响水滴所受的电场力。在80℃下,场强1500V/cm时有10%以上的水滴被分散,到场强5 000V/cm时则达到40%以上。场强超过7 000V/cm以后分散作用的增强逐步减弱。  相似文献   
992.
Stable propagation of synchronous spiking in cortical neural networks   总被引:25,自引:0,他引:25  
Diesmann M  Gewaltig MO  Aertsen A 《Nature》1999,402(6761):529-533
The classical view of neural coding has emphasized the importance of information carried by the rate at which neurons discharge action potentials. More recent proposals that information may be carried by precise spike timing have been challenged by the assumption that these neurons operate in a noisy fashion--presumably reflecting fluctuations in synaptic input and, thus, incapable of transmitting signals with millisecond fidelity. Here we show that precisely synchronized action potentials can propagate within a model of cortical network activity that recapitulates many of the features of biological systems. An attractor, yielding a stable spiking precision in the (sub)millisecond range, governs the dynamics of synchronization. Our results indicate that a combinatorial neural code, based on rapid associations of groups of neurons co-ordinating their activity at the single spike level, is possible within a cortical-like network.  相似文献   
993.
Wodarz A  Ramrath A  Kuchinke U  Knust E 《Nature》1999,402(6761):544-547
Asymmetric cell division generates daughter cells with different developmental fates from progenitor cells that contain localized determinants. During this division, the asymmetric localization of cell-fate determinants and the orientation of the mitotic spindle must be precisely coordinated. In Drosophila neuroblasts, inscuteable controls both spindle orientation and the asymmetric localization of the cell-fate determinants Prospero and Numb. Inscuteable itself is localized in an apical cortical crescent and thus reflects the intrinsic asymmetry of the neuroblast. Here we show that localization of Inscuteable depends on Bazooka, a protein containing three PDZ domains with overall sequence similarity to Par-3 of Caenorhabditis elegans. Bazooka and Inscuteable form a complex that also contains Staufen, a protein responsible for the asymmetric localization of prospero messenger RNA. We propose that, after delamination of the neuroblast from the neuroepithelium, Bazooka provides an asymmetric cue in the apical cytocortex that is required to anchor Inscuteable. As Bazooka is also responsible for the maintenance of apical-basal polarity in epithelial tissues, it may be the missing link between epithelial polarity and neuroblast polarity.  相似文献   
994.
Distribution of spatial and nonspatial information in dorsal hippocampus   总被引:10,自引:0,他引:10  
Hampson RE  Simeral JD  Deadwyler SA 《Nature》1999,402(6762):610-614
The hippocampus in the mammalian brain is required for the encoding of current and the retention of past experience. Previous studies have shown that the hippocampus contains neurons that encode information required to perform spatial and nonspatial short-term memory tasks. A more detailed understanding of the functional anatomy of the hippocampus would provide important insight into how such encoding occurs. Here we show that hippocampal neurons in the rat are distributed anatomically in distinct segments along the length of the hippocampus. Each longitudinal segment contains clusters of neurons that become active when the animal performs a task with spatial attributes. Within these same segments are ordered arrangements of neurons that encode the nonspatial aspects of the task appropriate to those spatial features. Thus, anatomical segregation of spatial information, together with the interleaved representation of nonspatial information, represents a structural framework that may help to resolve conflicting views of hippocampal function.  相似文献   
995.
Identification of in vivo substrates of the chaperonin GroEL   总被引:22,自引:0,他引:22  
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996.
A plant regulator controlling development of symbiotic root nodules   总被引:37,自引:0,他引:37  
Schauser L  Roussis A  Stiller J  Stougaard J 《Nature》1999,402(6758):191-195
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997.
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1000.
Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana   总被引:21,自引:0,他引:21  
Arabidopsis thaliana (Arabidopsis) is unique among plant model organisms in having a small genome (130-140 Mb), excellent physical and genetic maps, and little repetitive DNA. Here we report the sequence of chromosome 2 from the Columbia ecotype in two gap-free assemblies (contigs) of 3.6 and 16 megabases (Mb). The latter represents the longest published stretch of uninterrupted DNA sequence assembled from any organism to date. Chromosome 2 represents 15% of the genome and encodes 4,037 genes, 49% of which have no predicted function. Roughly 250 tandem gene duplications were found in addition to large-scale duplications of about 0.5 and 4.5 Mb between chromosomes 2 and 1 and between chromosomes 2 and 4, respectively. Sequencing of nearly 2 Mb within the genetically defined centromere revealed a low density of recognizable genes, and a high density and diverse range of vestigial and presumably inactive mobile elements. More unexpected is what appears to be a recent insertion of a continuous stretch of 75% of the mitochondrial genome into chromosome 2.  相似文献   
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