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41.
Eight glacial cycles from an Antarctic ice core 总被引:9,自引:0,他引:9
Augustin L Barbante C Barnes PR Barnola JM Bigler M Castellano E Cattani O Chappellaz J Dahl-Jensen D Delmonte B Dreyfus G Durand G Falourd S Fischer H Flückiger J Hansson ME Huybrechts P Jugie G Johnsen SJ Jouzel J Kaufmann P Kipfstuhl J Lambert F Lipenkov VY Littot GC Longinelli A Lorrain R Maggi V Masson-Delmotte V Miller H Mulvaney R Oerlemans J Oerter H Orombelli G Parrenin F Peel DA Petit JR Raynaud D Ritz C Ruth U Schwander J Siegenthaler U Souchez R Stauffer B Steffensen JP Stenni B 《Nature》2004,429(6992):623-628
The Antarctic Vostok ice core provided compelling evidence of the nature of climate, and of climate feedbacks, over the past 420,000 years. Marine records suggest that the amplitude of climate variability was smaller before that time, but such records are often poorly resolved. Moreover, it is not possible to infer the abundance of greenhouse gases in the atmosphere from marine records. Here we report the recovery of a deep ice core from Dome C, Antarctica, that provides a climate record for the past 740,000 years. For the four most recent glacial cycles, the data agree well with the record from Vostok. The earlier period, between 740,000 and 430,000 years ago, was characterized by less pronounced warmth in interglacial periods in Antarctica, but a higher proportion of each cycle was spent in the warm mode. The transition from glacial to interglacial conditions about 430,000 years ago (Termination V) resembles the transition into the present interglacial period in terms of the magnitude of change in temperatures and greenhouse gases, but there are significant differences in the patterns of change. The interglacial stage following Termination V was exceptionally long--28,000 years compared to, for example, the 12,000 years recorded so far in the present interglacial period. Given the similarities between this earlier warm period and today, our results may imply that without human intervention, a climate similar to the present one would extend well into the future. 相似文献
42.
Holman MJ Kavelaars JJ Grav T Gladman BJ Fraser WC Milisavljevic D Nicholson PD Burns JA Carruba V Petit JM Rousselot P Mousis O Marsden BG Jacobson RA 《Nature》2004,430(7002):865-867
Each giant planet of the Solar System has two main types of moons. 'Regular' moons are typically larger satellites with prograde, nearly circular orbits in the equatorial plane of their host planets at distances of several to tens of planetary radii. The 'irregular' satellites (which are typically smaller) have larger orbits with significant eccentricities and inclinations. Despite these common features, Neptune's irregular satellite system, hitherto thought to consist of Triton and Nereid, has appeared unusual. Triton is as large as Pluto and is postulated to have been captured from heliocentric orbit; it traces a circular but retrograde orbit at 14 planetary radii from Neptune. Nereid, which exhibits one of the largest satellite eccentricities, is believed to have been scattered from a regular satellite orbit to its present orbit during Triton's capture. Here we report the discovery of five irregular moons of Neptune, two with prograde and three with retrograde orbits. These exceedingly faint (apparent red magnitude m(R) = 24.2-25.4) moons, with diameters of 30 to 50 km, were presumably captured by Neptune. 相似文献
43.
Sauvan C Lalanne P Hugonin JP 《Nature》2004,429(6988):1 p following 154; discussion 2 p following 154
One challenge in photonics is strongly to confine light in small volumes in order to increase light-matter interaction. Akahane et al. propose a new concept for increasing the lifetime of this interaction, based on tailoring of the Fourier spectrum of cavity modes, which they believe is demonstrated by the surprising enhancement (roughly tenfold) of the quality factor Q of the cavity as a result of fine-tuning the mirror-hole geometry in a photonic-crystal nanocavity. Here we question the validity of their concept and argue that the improvement in Q is due to an increase in the impedance wave matching at the cavity edges and to a slow-wave effect. This alternative interpretation opens the way to new cavity designs. 相似文献
44.
Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype 总被引:2,自引:0,他引:2
Jaillon O Aury JM Brunet F Petit JL Stange-Thomann N Mauceli E Bouneau L Fischer C Ozouf-Costaz C Bernot A Nicaud S Jaffe D Fisher S Lutfalla G Dossat C Segurens B Dasilva C Salanoubat M Levy M Boudet N Castellano S Anthouard V Jubin C Castelli V Katinka M Vacherie B Biémont C Skalli Z Cattolico L Poulain J De Berardinis V Cruaud C Duprat S Brottier P Coutanceau JP Gouzy J Parra G Lardier G Chapple C McKernan KJ McEwan P Bosak S Kellis M Volff JN Guigó R Zody MC Mesirov J Lindblad-Toh K 《Nature》2004,431(7011):946-957
Tetraodon nigroviridis is a freshwater puffer fish with the smallest known vertebrate genome. Here, we report a draft genome sequence with long-range linkage and substantial anchoring to the 21 Tetraodon chromosomes. Genome analysis provides a greatly improved fish gene catalogue, including identifying key genes previously thought to be absent in fish. Comparison with other vertebrates and a urochordate indicates that fish proteins have diverged markedly faster than their mammalian homologues. Comparison with the human genome suggests approximately 900 previously unannotated human genes. Analysis of the Tetraodon and human genomes shows that whole-genome duplication occurred in the teleost fish lineage, subsequent to its divergence from mammals. The analysis also makes it possible to infer the basic structure of the ancestral bony vertebrate genome, which was composed of 12 chromosomes, and to reconstruct much of the evolutionary history of ancient and recent chromosome rearrangements leading to the modern human karyotype. 相似文献
45.
In the hydrothermal circulation at mid-ocean ridges, sea water penetrates the fractured crust, becomes heated by its proximity to the hot magma, and returns to the sea floor as hot fluids enriched in various chemical elements. In contradiction to earlier results that predict diminishing hydrothermal activity with decreasing spreading rate, a survey of the ultra-slowly spreading Gakkel Ridge (Arctic Ocean) by Edmonds et al. and Michael et al. suggests that, instead of being rare, the hydrothermal activity is abundant--exceeding by at least a factor of two to three what would be expected by extrapolation from observation on faster spreading ridges. Here we use helium-3 (3He), a hydrothermal tracer, to show that this abundance of venting sites does not translate, as would be expected, into an anomalous hydrothermal 3He output from the ridge. Because of the wide implications of the submarine hydrothermal processes for mantle heat and mass fluxes to the ocean, these conflicting results call for clarification of the link between hydrothermal activity and crustal production at mid-ocean ridges. 相似文献
46.
47.
Reboul J Vaglio P Rual JF Lamesch P Martinez M Armstrong CM Li S Jacotot L Bertin N Janky R Moore T Hudson JR Hartley JL Brasch MA Vandenhaute J Boulton S Endress GA Jenna S Chevet E Papasotiropoulos V Tolias PP Ptacek J Snyder M Huang R Chance MR Lee H Doucette-Stamm L Hill DE Vidal M 《Nature genetics》2003,34(1):35-41
To verify the genome annotation and to create a resource to functionally characterize the proteome, we attempted to Gateway-clone all predicted protein-encoding open reading frames (ORFs), or the 'ORFeome,' of Caenorhabditis elegans. We successfully cloned approximately 12,000 ORFs (ORFeome 1.1), of which roughly 4,000 correspond to genes that are untouched by any cDNA or expressed-sequence tag (EST). More than 50% of predicted genes needed corrections in their intron-exon structures. Notably, approximately 11,000 C. elegans proteins can now be expressed under many conditions and characterized using various high-throughput strategies, including large-scale interactome mapping. We suggest that similar ORFeome projects will be valuable for other organisms, including humans. 相似文献
48.
49.
Cloning of adiponectin receptors that mediate antidiabetic metabolic effects 总被引:231,自引:0,他引:231
Yamauchi T Kamon J Ito Y Tsuchida A Yokomizo T Kita S Sugiyama T Miyagishi M Hara K Tsunoda M Murakami K Ohteki T Uchida S Takekawa S Waki H Tsuno NH Shibata Y Terauchi Y Froguel P Tobe K Koyasu S Taira K Kitamura T Shimizu T Nagai R Kadowaki T 《Nature》2003,423(6941):762-769
Adiponectin (also known as 30-kDa adipocyte complement-related protein; Acrp30) is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Levels of adiponectin in the blood are decreased under conditions of obesity, insulin resistance and type 2 diabetes. Administration of adiponectin causes glucose-lowering effects and ameliorates insulin resistance in mice. Conversely, adiponectin-deficient mice exhibit insulin resistance and diabetes. This insulin-sensitizing effect of adiponectin seems to be mediated by an increase in fatty-acid oxidation through activation of AMP kinase and PPAR-alpha. Here we report the cloning of complementary DNAs encoding adiponectin receptors 1 and 2 (AdipoR1 and AdipoR2) by expression cloning. AdipoR1 is abundantly expressed in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. These two adiponectin receptors are predicted to contain seven transmembrane domains, but to be structurally and functionally distinct from G-protein-coupled receptors. Expression of AdipoR1/R2 or suppression of AdipoR1/R2 expression by small-interfering RNA supports our conclusion that they serve as receptors for globular and full-length adiponectin, and that they mediate increased AMP kinase and PPAR-alpha ligand activities, as well as fatty-acid oxidation and glucose uptake by adiponectin. 相似文献
50.
Toppani A Robert F Libourel G de Donato P Barres O d'Hendecourt L Ghanbaja J 《Nature》2005,437(7062):1121-1124
The signature of carbonate minerals has long been suspected in the mid-infrared spectra of various astrophysical environments such as protostars. Abiogenic carbonates are considered as indicators of aqueous mineral alteration in the presence of CO2-rich liquid water. The recent claimed detection of calcite associated with amorphous silicates in two planetary nebulae and protostars devoid of planetary bodies questions the relevance of this indicator; but in the absence of an alternative mode of formation under circumstellar conditions, this detection remains controversial. The main dust component observed in circumstellar envelopes is amorphous silicates, which are thought to have formed by non-equilibrium condensation. Here we report experiments demonstrating that carbonates can be formed with amorphous silicates during the non-equilibrium condensation of a silicate gas in a H2O-CO2-rich vapour. We propose that the observed astrophysical carbonates have condensed in H2O(g)-CO2(g)-rich, high-temperature and high-density regions such as evolved stellar winds, or those induced by grain sputtering upon shocks in protostellar outflows. 相似文献