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11.
Gin McCollum 《Foundations of Science》2002,7(1-2):49-72
Nervous systems are intricately organized on many levels of analysis.The intricate organization invites the development of mathematicalsystems that reflect its logical structure. Particular logical structures and choices of invariants within those structures narrowthe ranges of perceptions that are possible and sensorimotorcoordination that may be selected. As in quantum logic, choicesaffect outcomes. Some of the mathematical tools in use in quantum logic havealready also been used in neurobiology, including the mathematicsof ordered structures and a product like a tensor product. Astheoretical neurobiology is developed on its own foundation, wemay expect a rich dialogue between theoretical neurobiology andquantum logic. 相似文献
12.
管延勇 《济南大学学报(自然科学版)》1994,(1)
Shevrin提出了一个公开问题,即子半群格是可补格的半群是否是周期的。本文进一步证明了对逆半群、矩形群及幕等元集是左(右)正规带的E─右(左)么正正则半群,使公开问题有了肯定的回答。 相似文献
13.
矿井提升机PLC电控系统技术改造浅析 总被引:3,自引:0,他引:3
随着科技高新技术发展,微机保护技术已广泛应用于电力系统,文章分析了提升机电控系统进行PLC控制技术改造,可编程程序控制,保护功能齐全. 相似文献
14.
Quesada V Conde L Villamor N Ordóñez GR Jares P Bassaganyas L Ramsay AJ Beà S Pinyol M Martínez-Trillos A López-Guerra M Colomer D Navarro A Baumann T Aymerich M Rozman M Delgado J Giné E Hernández JM González-Díaz M Puente DA Velasco G Freije JM Tubío JM Royo R Gelpí JL Orozco M Pisano DG Zamora J Vázquez M Valencia A Himmelbauer H Bayés M Heath S Gut M Gut I Estivill X López-Guillermo A Puente XS Campo E López-Otín C 《Nature genetics》2012,44(1):47-52
Here we perform whole-exome sequencing of samples from 105 individuals with chronic lymphocytic leukemia (CLL), the most frequent leukemia in adults in Western countries. We found 1,246 somatic mutations potentially affecting gene function and identified 78 genes with predicted functional alterations in more than one tumor sample. Among these genes, SF3B1, encoding a subunit of the spliceosomal U2 small nuclear ribonucleoprotein (snRNP), is somatically mutated in 9.7% of affected individuals. Further analysis in 279 individuals with CLL showed that SF3B1 mutations were associated with faster disease progression and poor overall survival. This work provides the first comprehensive catalog of somatic mutations in CLL with relevant clinical correlates and defines a large set of new genes that may drive the development of this common form of leukemia. The results reinforce the idea that targeting several well-known genetic pathways, including mRNA splicing, could be useful in the treatment of CLL and other malignancies. 相似文献