The finished DNA sequence of human chromosome 12

Human chromosome 12 contains more than 1,400 coding genes and 487 loci that have been directly implicated in human disease. The q arm of chromosome 12 contains one of the largest blocks of linkage disequilibrium found in the human genome. Here we present the finished sequence of human chromosome 12, which has been finished to high quality and spans approximately 132 megabases, representing approximately 4.5% of the human genome. Alignment of the human chromosome 12 sequence across vertebrates reveals the origin of individual segments in chicken, and a unique history of rearrangement through rodent and primate lineages. The rate of base substitutions in recent evolutionary history shows an overall slowing in hominids compared with primates and rodents.     

VARIATION OF WOVEN FABRIC GEOMETRY——Non-uniform Flattening of Yarns

In previous research much effort has been devoted to the geometry of woven fabrics and relat-ed problems under the assumption of constant yarn configuration in fabric.This paper will first re-port that image crimp (yarn crimp measured by an image analysis method) seems larger than actualvalue.From the explanation of this result,the variation of yarn configuration in woven fabric dueto the non-uniform flattening is revealed.The significance of this actual structure of woven fabricsis discussed.It is believed that the variation of yarn configuration is very important for fabric per-formance,and may be an advantage for fabric quality.