构建科技中介体系 促进科技成果转化——上海科技中介的瓶颈和对策研究

笔者指出，通过调研发现，上海的科技中介体系薄弱是影响科技成果转化的瓶颈之一。针对这个问题，文章介绍了上海科技中介服务取得的基本成绩，分析了上海科技中介服务存在的主要问题，提出了发展科技中介服务的对策和建议。     

沥青混凝土路面水损害防治措施浅谈

沥青路面的水损害问题是公路工程的通病之一；本文分析了沥青路面水损坏发生机理与相关因素，对沥青路面水损害产生的危害进行剖析，并针对性地提出了控制水损害出现的相应措施。     

关于提高PLC控制系统可靠性的研究

可编程控制器在工业生产中的应用极为广泛,如何保证其可靠性成为系统设计中一个不可忽视的问题。本文从提高可靠性入手,对系统的软硬件设计进行了综合分析和说明,便于相关技术人员在系统设计施工过程中参考应用。     

曲安京、姚远主持的课题分获中国科学院知识创新工程项目资助

20 0 0年 1 1月 1 2日在北京结束的中国科学院综合计划局课题启动工作会议表明 ,我校数学与科学技术史研究中心曲安京教授主持的“中国近现代奖励制度之研究”和学报编辑部姚远编审主持的“中国近现代科学技术期刊研究”分获 3.8万元和 3万元的资助 ,另外相应配套有出版资助。学报编辑部张银玲副编审、徐象平副编审和博士生尚宇红等均参与该课题。这两项课题属于中国科学院知识创新工程项目“中国近现代科学技术发展综合研究”的二级课题 ,均为中国科学院重点科研项目 ,总资助额达 350余万元。该课题将形成由路甬祥院长总主编的《中国近现代…     

Antioxidant activity of N-acetyl-glucosamine based thiazolidine derivative

N-acetyl-glucosamine,the monomer of chitin,was cyclo-condensed with L-cysteine to prepare thiazolidine derivative2-N-acetyl-glucosamine-thiazolidine-4(R)-carboxylic acid(GlcNAcCys).The stability of GlcNAcCys was evaluated by high performance liquid chromatography(HPLC)measurement.The results showed that GlcNAcCys Was more stable than other TCA derivatives,especially in alkaline condition.The direct in vitro antioxidative properties of GlcNAcCys were investigated by using UV radiation-induced lipid peroxidation(LPO)in mitochondria and nuclei and.OH-induced LPO in red blood cell (RBC)ghosts models.UV radiation caused dose-dependent LPO in both mitochondria and nuclei,this effect Was catalvzed by addition of Fd2 while prevented by co-incubation with GlcNAcCys.When nuclei and mitochondria Was treated with 100μl,300μl,500μl of GlcNAcCys and co-incubated at 37℃ for 30min,LPO was decreased to 96%,72%,68%in nuclei and 95%,72%,68% in mitochondria when compared to the UV radiation group respectively.Hydroxyl radicals(.OH)generated by Fenton reaction induced LPO in RBC ghosts.Pretreatment of RBC ghosts with GlcNAcCys could induce antioxidant RBC ghosts and inhibit concentration-dependent malondialdehyde(MDA)formation in antioxidant RBC ghosts.Its inhibition percent Was 14%,35%,36%,42%at 10,20,30,40ms/ml respectively.In a conclusion,the data suggest that GlcNAcCys has antioxidant ability and can significantly inhibit lipid peroxidation in biological samples tested in vitro.