工程建设用地信息管理系统的研究

工程建设用地信息管理系统”是“工程建设用地辅助决策支持系统”的一个子系统，它对土地管理部门的基础资料和信息进行统一分类和集中管理．本文对该系统从研制背景、数据库结构、整体结构、基本技术和未来发展几个方面，作一详细论述．     

鸡大肠杆菌病的现状与综合防治

从病原、流行病学、临床症状、诊断、防治等方面，对鸡大肠杆菌病的发病现状与综合防治进行了论述，为肉鸡、蛋鸡养殖生产中大肠杆菌病的诊断和综合防治提供了有意义的建议。     

Cyclosporine is angiostatic

The systemic effect of the immunosuppressive drug cyclosporine (CS) on formation of new blood vessels was studied quantitatively in rats using the mesenteric-window assay. Angiogenesis was induced by i.p. injection of saline. CS at a s.c. dose of 4 mg/kg/day, which is in the range used clinically, suppressed angiogenesis (inhibiting branching or tortuosity more than spatial expansion), and appeared to be non-toxic. This is the first report on an apparently selective angiostatic effect of CS. The finding is likely to have implications for the clinical use of CS, not only in certain types of organ transplantation but possibly also in psoriasis and other angiogenesis-dependent diseases.     

Mutation of the matrix metalloproteinase 2 gene (MMP2) causes a multicentric osteolysis and arthritis syndrome.

The inherited osteolyses or 'vanishing bone' syndromes are a group of rare disorders of unknown etiology characterized by destruction and resorption of affected bones. The multicentric osteolyses are notable for interphalangeal joint erosions that mimic severe juvenile rheumatoid arthritis (OMIMs 166300, 259600, 259610 and 277950). We recently described an autosomal recessive form of multicentric osteolysis with carpal and tarsal resorption, crippling arthritic changes, marked osteoporosis, palmar and plantar subcutaneous nodules and distinctive facies in a number of consanguineous Saudi Arabian families. We localized the disease gene to 16q12-21 by using members of these families for a genome-wide search for homozygous-by-descent microsatellite markers. Haplotype analysis narrowed the critical region to a 1.2-cM region that spans the gene encoding MMP-2 (gelatinase A, collagenase type IV; (ref. 3). We detected no MMP2 enzymatic activity in the serum or fibroblasts of affected family members. We identified two family-specific homoallelic MMP2 mutations: R101H and Y244X. The nonsense mutation effects a deletion of the substrate-binding and catalytic sites and the fibronectin type II-like and hemopexin/TIMP2 binding domains. Based on molecular modeling, the missense mutation disrupts hydrogen bond formation within the highly conserved prodomain adjacent to the catalytic zinc ion.     

现行科技成果奖励办法的利弊分析与对策初探

文章对现行科技成果奖励办法的利弊进行了分析探讨，并提出了相相应对策建议。     

谈中国术语学的理论建设

本文论述了中国术语学建设的灵魂是理论，而理论建设需要的途径有四条：继承，借鉴，移植、升华。     

基于BP神经网络的增益量化中的阶距自适应

本文分析了G.728语音编码算法增益固定量化的缺陷,设计了精确表示增益的自适应量化方案。采用BP神经网络对增益的量化步长进行非线性自适应量化,并提出一种新的用于训练BP神经网络的数据的获取方法。     

光辐射在光学纤维波导中的传输

从麦克斯韦方程出发，讨论了光学纤维波导中光辐射场的解，得到光辐射在光学纤维波导中的传播特征。     

Age distribution of circulatingα-interferon

Summary A sensitive radioimmunoassay showed that circulating -interferon in the plasma of healthy individuals was low in children and reached the highest level in the young adult, then declined gradually with age. Circulating -interferon was 0.201±0.059 ng/ml in males (n=19) and 0.184±0.076 ng/ml in females (n=14) at ages 30–39 years old. It was noted that circulating -interferon was maintained up to a certain level even in elderly individuals.