量子力学的经典极限与库仑散射

论述了量子力学的经典极限问题,并运用狄拉克判据研究了库仑散射的经典极限;指出库仑散射存在一经典极限的“黑箱”禁区,在经典极限的“黑箱”禁区以外,库仑散射的经典理论是量子理论的很好近似。     

二(1-苯基-3-甲基-4-苯甲酰吡唑啉酮-5)合钯(Ⅱ)的热分解机理

报道了二（１－苯基－３－甲基－４－苯甲酰吡唑啉酮－５）合钯（Ⅱ）的合成、红外表征及非等温热分解动力学．采用微分和积分相结合的方法,推断出了可能的热分解机理及热力学方程．     

Preparation of the selenomethionine derivative of tabtoxin resistance protein

In order to obtain phase information for the X-ray diffraction of tabtoxin resistance protein (TTR) crystal using the MAD phasing method, a selenomethionine (Se-Met) derivative of TTR was overexpressed in E. coli strain M15, with pQE-30 plasmid, through IPTG induction in M9 medium containing Se-Met. The product was purified to an estimated homogeneity of greater than 95% according to SDS-PAGE, by a Ni-NTA metal affinity followed by a Mono Q anion exchange column chromatography. The successful substitution of Se-Met for methionine (Met) was confirmed by MALDI-TOF and ESI-Quadrupole Mass Spectrometry analysis. The derivative crystal was obtained using similar conditions as those for the native.     

神经网络的遗传设计及其在甲醛生产建模及优化中的应用

采用遗传算法的机制设计了一种同时对前向网络的连接权值及拓扑结构进行搜索的方法，并采用以隐结点为基本基因型的方式，同时在算法中加入了局部搜索的方法．该算法已被应用于甲醛生产过程的建模及优化，达到了良好的效果．     

Lidamycin inhibits tumor growth and pulmonary metastasis in murine breast carcinoma and shows synergy with paclitaxel

The main goal of this study was to investigate whether lidamycin (LDM) could enhance the efficacy of paclitaxel (TAX) against breast cancer. In the MTT assay, LDM showed much more potent cytotoxicity than paclitaxel, and there was a synergy on the 4T1/luc breast cancer cells treated with a combination of paclitaxel and LDM. Western blot analysis showed that paclitaxel and LDM synergistically downregulated MMP9, MMP2, VEGF, and upregulated the cleaved PARP proteins. By wound closure cell migration assay, paclitaxel combined LDM obviously inhibited the migration of 4T1/luc cells. At therapeutic dosage level, LDM, paclitaxel, and the combination suppressed the pulmonary metastases by 70.2%, 53.8%, and 88.7%, respectively, and the CDI value was 0.82, indicating synergism. The results show that LDM enhances the antitumor effect of paclitaxel on 4T1/luc breast cancer, in particular, the antimetastatic effects on pulmonary metastasis.     

奶牛乳房炎的病因分析

对引起奶牛乳房炎的病原微生物，包括接触传染性病原菌和环境性病原菌的种类及症状做了阐述与分析。     

多目标混流装配计划排序问题

在总结混流装配线排序问题的优化目标基础上,给出了一种混流装配线排序多目标优化模型.采用一种染色体映射的策略,有效地解决了遗传算法中染色体变化后难以保证主生产计划约束的问题.对比计算的结果表明:多目标计划排序不仅能有效保证基于生产负荷平衡的目标和基于物流平顺化的目标的要求,同时还能减少装配中品种切换频繁的问题.     

超声波振动切削时振动刀具对工件的冲击作用

通过实验,明确了影响振动切削效果的主要因素,认清了超声振动切削对切削过程所起的作用。推导出振动刀具与回转工件在接触瞬间产生碰撞的功能损失公式,并对该能量在切削过程中所起的作用及获得最佳效果所需要的条件进行了研究。     

胶结液参数对微生物加固粉土的影响

胶结液对微生物土体加固具有重要作用,以海相粉土为处理对象,选用巴氏芽孢杆菌作为微生物、尿素和氯化钙作为胶结液,研究胶结液参数对加固效果的影响.采用将菌液与粉土拌合制样,然后入渗多轮胶结液的方法对试样进行有效加固.通过试验研究了浓度、轮数、配比、体积等胶结液参数对加固效果的影响.结果 表明:当胶结液浓度不低于0.50 m...     

受载试剂在二环倍半萜类天然产物全合成中的应用

在二环倍半萜天然产物的全合成过程,使用SeO2/SiO2、CuSO4/S2O2、FeCl/SiO2等受载试剂,有效地完成了烯丙位选择性氧化、脱水及性缩硫酮化等反应。