Review： Deregulation of microRNA expression in thyroid tumors

MicroRNAs （miRNAs or miRs） are endogenous non-coding RNAs that negatively regulate gene expres- sion by binding to the 3＇ non-coding regions of target mRNAs, resulting in their cleavage or blocking their translation. miRNAs may have an impact on cell differentiation, proliferation, and survival, and their deregulation can be inclined to diseases and cancers, including thyroid tumors. The purpose of this review is to summarize the existing findings of deregulated miRNAs in different types of thyroid tumors and to exhibit their potential target genes, especially to demonstrate those involved in tumor invasion and metastasis. In addition, new findings of circulating miRNA expres- sion profiles, single nucleotide polymorphism （SNP） in thyroid tumors, and the correlation of somatic mutations with deregulated miRNA expression in thyroid tumors were all included in this review.     

基于计算思维的数据库教学思考与探索

针对数据库教学目前存在的问题和计算思维理论的发展,提出基于计算思维的数据库课程教学措施,通过建立计算思维的全局观,明确各知识点所用到的计算思维方法,面向应用进行讲解和提供真实案例,提高学生的计算思维能力和学习兴趣。     

论行政赔偿范围的扩大

对我国目前的行政赔偿范围进行了反思。认为我国现行的《国家赔偿法》主要以列举方式确定的行政赔偿范围,极大限制了行政赔偿范围。建议采取“概括加否定排除式”的立法模式扩大行政赔偿范围,将行政规章以下的抽象行政行为、行政不作为行为和精神损害赔偿纳入行政赔偿范围。     

浅谈我国古汉字的绘画艺术美

本文从绘画的角度，阐释了古汉字的起源、演变以及汉字本身所蕴含的绘画艺术美和书法艺术。     

实验室水槽装置液位模糊控制系统的设计

介绍一种带修正因子和寻优参数的水位模糊控制系统。实验表明 ,该系统具有较强的抗干扰能力及适应内部参数变化的能力。阐述了控制方案及软、硬件的设计。     

浅谈节能型循环流化床垃圾焚烧发电锅炉的设计

将炉排式垃圾焚烧锅炉与循环流化床垃圾焚烧锅炉进行比较.指出设计循环流化床垃圾焚烧锅炉时应重点考虑的问题,提出新一代循环流化床垃圾焚烧锅炉设计的关键点.     

活性炭负载纳米零价铁去除溴酸盐的研究

实验采用液相还原法制备活性炭负载纳米零价铁材料(nZVI/AC),并利用X射线衍射(XRD)、扫描电镜(SEM)和透射电镜(TEM)等对其结构进行表征.考察了不同反应条件下nZVI/AC对BrO3-的去除效率,并研究其去除机理.结果表明nZVI/AC具有很高的表面反应活性,且nZVI和活性炭(AC)之间存在协同作用. BrO3-的去除效率随 pH 值的减小而增大, 共存离子NO3-和SO42-对其去除率影响不大但降低了去除速率.机理分析表明BrO3-被nZVI/AC吸附而使局部BrO3-浓度升高,并被nZVI迅速还原为无毒的Br-.     

Morphological control of zinc tricarbohydrazide perchlorate crystals: Theoretical and experimental study

The theoretical crystal-morphology of zinc tricarbohydrazide perchlorate (ZnCP) was studied using the morphology simulation software. The growth trends and surface characteristics were calculated using the Bravais-Friedel-Donnay- Harker (BFDH), Growth Morphology, and Equilibrium Morphology methods; these provide theoretical guidance for the choice of crystal-control reagents. On the basis of the simulations, experiments were carried out to study the effects of five different crystal-control reagents, including carboxymethylcellulose (A), polyacrylamide (B), dextrin (C), Tween 40 (D), and Tween 60 (E), in the control of the crystal-morphology of ZnCP. Mixtures of two reagents and higher temperatures were used to further optimize the ZnCP crystals. The results show that ZnCP crystals are well dispersed, and have a large apparent density and regular crystal-morphology under the control of a mixture of reagents A and E in a mass ratio of 1:4 at 80°C.     

库区高填方桥梁墩台位移病害及处治研究

库区某梁桥高填方桥台在施工过程中及通车后,个别墩台发生纵桥向位移病害,进行数值模拟计算,分析了病害成因,并对该桥梁病害处治进行了实践研究。最后总结提出库区高填方桥台的设计和施工中应注意的事项,应采取的措施及对策。     

带有强迫项的具分布型时滞的非线性系统的渐近性

研究了一类带有强迫项的具有连续型滞量的非线性微分方程组解的渐近性，进一步推广了文[6]中的主要结果，得到了系统的解趋于零的充分条件。