《河南植物志》虎耳草科补遗

报道了《河南植物志》中未记录的虎耳草科植物9种5变种(均采有标本)。     

Biosynthesis of 1-alkenes in the defensive secretions ofTribolium confusum (Tenebrionidae); stereochemical implications

Summary The terminally unsaturated hydrocarbons of the defensive secretion ofTribolium confusum are biosynthesized from fatty acids by oxidative decarboxylation. The process involves an enantiospecific cleavage of the C–H bond of thepro-(S) C(3)–H atom and simultaneous decarboxylation of the acid into an 1-alkene and carbon dioxide via ananti-periplanar transition state geometry (anti-elimination). The stereochemistry of this biotranformation is identical in all respects with the same reaction in higher plants. The mechanism seems to be of general importance for the biosynthesis of many vinylic substructures of natural products from oxygen-containing precursors.     

Experimentelle Reversion von Tumorzellen in vivo

Summary European eels with fast growing epidermal papillomas (cauliflower disease) were treated with quinine-sulphate. At concentrations of 15 to 60 mg/l and after 8 weeks of treatment, there occurred newly formed mucous cells and club cells in the tumor tissue. Tight contact between all cells was reestablished. The nucleus-plasma-relation had evidently decreased. Electron microscopical studies showed a restauration of degenerated cell organelles, especially of the outer membrane. Growth rate of the tumors was reduced, and at a concentration of 60 mg/l the tumor tissue ceased growing from the beginning of treatment.     

Wiederherstellung des normalen Herzschlages nach elektrisch erzeugtem Kammerflimmern durch Adenosintriphosphorsäure

Summary (1) In the isolated mammalian heart (rabbit, cat, dog) electrically induced ventricular fibrillation is stopped in practically 100% of the cases by adenosin-triphosphoric acid (ATP) in doses of 0.25–20 mg, and the normal rhythm of the heart is permanently restored (as far as the experiment extends).(2) This effect of ATP follows from a primary blocking, which leads to a complete cessation of the activity of the ventricles with diastolic dilatation of the heart.(3) In as much as adenyl acid from yeast and adenosin (in large doses) also stop ventricular fibrillation, the energetic effect of ATP seems to be of no importance in stopping it; it is a specific effect of the adenyl compounds on the bundle ofHis.     

Geschwindigkeit der selektiven Akkumulation von Mercurascan-203 im geschädigten Muskel und im ischämischen Myokard

Summary The authors demonstrate that a hydroxy derivative of fluorescein — Mercurascan 203 — very rapidly and selectively accumulates in the injured muscle and in the ischaemic myocardium and is cleared rapidly from the blood and other tissues. In vivo, scanning is positive soon after Mercurascan-203 administration.     

Mutagenic action of ethylene halogenhydrins

Zusammenfassung Eine stark mutagene Wirkung wird durch äthylenchlorhydrin, äthylenbromhydrin und äthylenjodhydrin aufKlebsiella pneumoniae ausgeübt.