碳纤维布在混凝土大梁加固中的应用

通过对某教学楼钢筋混凝土大梁的裂缝成因分析 ,针对该裂缝的特点 ,选择用碳纤维布进行加固 ,实践证明碳纤维布可以明显地提高钢筋混凝土梁的抗弯承载力     

养殖大黄鱼细菌性疾病的病原研究

从患病大黄鱼体内分离到二株病原菌，经人工感染试验及菌种鉴定研究，认为致病菌为熔藻弧菌Vibrio algi-nolyticus。药敏实验结果表明：磺胺 TMP、氯霉素、环丙沙星、呋喃妥因等对致病菌有较强的抑制作用。     

"恩七叶甜"绞股蓝总皂甙提取工艺研究

采用除离子水作溶剂,80℃减压提取,选用筛为1500分子量的滤膜超滤除杂,D101－A型树脂分离,活性碳精制方法提取“恩七叶甜”绞股蓝总皂甙,提取率90．8％,收得率92％,精制的总皂甙纯度99％。     

基于案例推理的知识库系统设计

基于案例推理技术是近年出现的具有一定的代表性的推理技术,利用这种技术进行知识库系统设计可简化问题,提高效率。从基于案例推理机制入手,阐述了基于案例推理知识库系统的工作过程和原理,提出了系统设计的方法。     

热分层环境下船模尾流温度分布与扩展规律试验研究

通过对船模在水槽中稳定热分层环境下运动后留下的尾流中的温度测量及红外摄像,试验研究了双螺旋桨船模在二种速度运动下,螺旋桨相对向内旋转、向外旋转及螺旋桨不工作时,船模尾流中的温度分布与扩展规律.     

一种新型的光纤荧光温度传感器

介绍一种基于稀土荧光材料（Y^2O^2S:Eu)温度－荧光特性的光纤荧光温度传感器,由紫外汞灯发出的紫外光补调制成脉冲激励光,通过光纤传输激发探头处的荧光材料产生荧光,通过测量两个峰值荧光信号的值得到输出与温度的关系,温度测量误差小于0．5℃。实验结果表明,文具该测系统能够有效地消除光源不稳定及测量通道中光强度化对测量 结果的影响。     

钢棒/环氧拔出试件界面端奇异应力场强度表征及其试验测试

传统复合材料界面强度细观试验采用界面端部脱粘时的剪切应力作为界面剪切强度的表征,而理论分析表明双材料界面端应力场存在奇异性。在分析拔出试件界面端应力奇异性的基础上,对钢棒/环氧复合材料在宏观尺度进行断裂韧性的试验测试,所得结果与压入试件界面端试验结果比较,表明不同类型界面端断裂韧性也不相同,其中原因有待深入研究与分析。     

数据仓库技术研究

数据仓库是近几年数据库领域研究的热点问题之一 ,也是决策支持系统 ( DSS)与数据库技术的结合点。在对传统的数据库与数据仓库的实现技术进行分析的基础上 ,讨论了数据仓库的实现过程、关键环节及相关技术。     

Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors

H5N1 influenza A viruses have spread to numerous countries in Asia, Europe and Africa, infecting not only large numbers of poultry, but also an increasing number of humans, often with lethal effects. Human and avian influenza A viruses differ in their recognition of host cell receptors: the former preferentially recognize receptors with saccharides terminating in sialic acid-alpha2,6-galactose (SAalpha2,6Gal), whereas the latter prefer those ending in SAalpha2,3Gal (refs 3-6). A conversion from SAalpha2,3Gal to SAalpha2,6Gal recognition is thought to be one of the changes that must occur before avian influenza viruses can replicate efficiently in humans and acquire the potential to cause a pandemic. By identifying mutations in the receptor-binding haemagglutinin (HA) molecule that would enable avian H5N1 viruses to recognize human-type host cell receptors, it may be possible to predict (and thus to increase preparedness for) the emergence of pandemic viruses. Here we show that some H5N1 viruses isolated from humans can bind to both human and avian receptors, in contrast to those isolated from chickens and ducks, which recognize the avian receptors exclusively. Mutations at positions 182 and 192 independently convert the HAs of H5N1 viruses known to recognize the avian receptor to ones that recognize the human receptor. Analysis of the crystal structure of the HA from an H5N1 virus used in our genetic experiments shows that the locations of these amino acids in the HA molecule are compatible with an effect on receptor binding. The amino acid changes that we identify might serve as molecular markers for assessing the pandemic potential of H5N1 field isolates.