Simulations of the formation, evolution and clustering of galaxies and quasars

The cold dark matter model has become the leading theoretical picture for the formation of structure in the Universe. This model, together with the theory of cosmic inflation, makes a clear prediction for the initial conditions for structure formation and predicts that structures grow hierarchically through gravitational instability. Testing this model requires that the precise measurements delivered by galaxy surveys can be compared to robust and equally precise theoretical calculations. Here we present a simulation of the growth of dark matter structure using 2,160(3) particles, following them from redshift z = 127 to the present in a cube-shaped region 2.230 billion lightyears on a side. In postprocessing, we also follow the formation and evolution of the galaxies and quasars. We show that baryon-induced features in the initial conditions of the Universe are reflected in distorted form in the low-redshift galaxy distribution, an effect that can be used to constrain the nature of dark energy with future generations of observational surveys of galaxies.     

Melatonin,clock genes and mitochondria in sepsis

After the characterization of the central pacemaker in the suprachiasmatic nucleus, the expression of clock genes was identified in several peripheral tissues including the immune system. The hierarchical control from the central clock to peripheral clocks extends to other functions including endocrine, metabolic, immune, and mitochondrial responses. Increasing evidence links the disruption of the clock genes expression with multiple diseases and aging. Chronodisruption is associated with alterations of the immune system, immunosenescence, impairment of energy metabolism, and reduction of pineal and extrapineal melatonin production. Regarding sepsis, a condition coursing with an exaggerated response of innate immunity, experimental and clinical data showed an alteration of circadian rhythms that reflects the loss of the normal oscillation of the clock. Moreover, recent data point to that some mediators of the immune system affects the normal function of the clock. Under specific conditions, this control disappears reactivating the immune response. So, it seems that clock gene disruption favors the innate immune response, which in turn induces the expression of proinflammatory mediators, causing a further alteration of the clock. Here, the clock control of the mitochondrial function turns off, leading to a bioenergetic decay and formation of reactive oxygen species that, in turn, activate the inflammasome. This arm of the innate immunity is responsible for the huge increase of interleukin-1β and entrance into a vicious cycle that could lead to the death of the patient. The broken clock is recovered by melatonin administration, that is accompanied by the normalization of the innate immunity and mitochondrial homeostasis. Thus, this review emphasizes the connection between clock genes, innate immunity and mitochondria in health and sepsis, and the role of melatonin to maintain clock homeostasis.     

Air Pollution,Government Pollution Regulation,and Industrial Production in China

Over the last four decades, a severe deterioration in air quality has accompanied China's rapid industrialization. As a result, the Chinese government has implemented stricter policies and regulation to control air pollution. In this paper, the authors create a measure of government policies on air pollution by tracking all pollution-related government announcements in Chinese newspapers. The authors then use this variable, along with measures of actual pollution, to investigate how air pollution,industrial production, and government policies on air pollution are interrelated. The authors conduct this investigation nationwide, as well as in five large cities in China. A vector autoregression model suggests that, nationwide, government policies seem to decrease air pollution without significantly affecting industrial production. However, the effect appears to be short-lived, dissipating after a few months. In addition, the authors find that the dynamic relationship among these variables differs by city. For instance, following an adverse air quality shock in Beijing, government efforts to control pollution seem to have an ameliorating city-wide effect, decreasing local air pollution in subsequent months. In Shanghai and Guangzhou, while the local government reacts to adverse air pollution shocks,the ameliorating effects are not statistically significant. In Chengdu and Shenyang, the authors detect no significant local government reaction to adverse air pollution shocks. Moreover, in these cities, local government policies do not impart a statistically measurable effect on air pollution.     

Primary forests are irreplaceable for sustaining tropical biodiversity

Human-driven land-use changes increasingly threaten biodiversity, particularly in tropical forests where both species diversity and human pressures on natural environments are high. The rapid conversion of tropical forests for agriculture, timber production and other uses has generated vast, human-dominated landscapes with potentially dire consequences for tropical biodiversity. Today, few truly undisturbed tropical forests exist, whereas those degraded by repeated logging and fires, as well as secondary and plantation forests, are rapidly expanding. Here we provide a global assessment of the impact of disturbance and land conversion on biodiversity in tropical forests using a meta-analysis of 138 studies. We analysed 2,220 pairwise comparisons of biodiversity values in primary forests (with little or no human disturbance) and disturbed forests. We found that biodiversity values were substantially lower in degraded forests, but that this varied considerably by geographic region, taxonomic group, ecological metric and disturbance type. Even after partly accounting for confounding colonization and succession effects due to the composition of surrounding habitats, isolation and time since disturbance, we find that most forms of forest degradation have an overwhelmingly detrimental effect on tropical biodiversity. Our results clearly indicate that when it comes to maintaining tropical biodiversity, there is no substitute for primary forests.     

Action Research for Emancipation Informed by Habermas and Hierarchy of Systems: Case Study on Environmental Education and Management of Water Resources in Brazil

Technology is used in order to emancipate. Emancipation for social and environmental justice ought to shape the way technology is designed and used. The relationships across action research, action research spiral, and the General Systems Theory was investigated. The case study refers to environmental education activities as part of a participative management approach to water resources on the Hydrographic Basin of the Upper Maranhão River (Brazil). By introducing action research spiral as a search of rationality in social practices, and describing the nature of lower and higher hierarchical level in General Systems Theory, the higher hierarchical level was associated with Habermasian emancipatory interest, whereas lower hierarchic levels were associated with the specific instrumental concern. To conclude, it is said that the articulation between action research spiral and General System Theory can be the means to strengthen the dialectical potential of the action research spiral in order to achieve both individual and collective empowerment.     

The large-scale structure of the Universe

Research over the past 25 years has led to the view that the rich tapestry of present-day cosmic structure arose during the first instants of creation, where weak ripples were imposed on the otherwise uniform and rapidly expanding primordial soup. Over 14 billion years of evolution, these ripples have been amplified to enormous proportions by gravitational forces, producing ever-growing concentrations of dark matter in which ordinary gases cool, condense and fragment to make galaxies. This process can be faithfully mimicked in large computer simulations, and tested by observations that probe the history of the Universe starting from just 400,000 years after the Big Bang.