模压工艺参数对聚酰亚胺树脂压缩强度的影响及其数学模型的建立

研究了模压温度、保温时间对聚酰亚胺树脂强度的影响,并建立了这些工艺参数与树脂强度的数学模型.研究结果表明,热压成型过程中的成型工艺会显著影响聚酰亚胺树脂的强度.当成型温度为653 K、无压力时的保温时间为25 min时,聚酰亚胺树脂的压缩强度达到最大值.通过正交中心复合设计,拟合得到的多元二次方程式可以在研究范围内充分描述聚酰亚胺树脂的压缩强度特性.     

腾格里沙漠南缘全新世古气候变化初步研究

通过对腾格里沙漠南缘红水河剖面的地层分析和年代序列建立，依据分辨率４０￣５０ａ的ＴＯＣ、ＴＩＣ、元素和稳定同位素（δ＾１８Ｏ）分析及孢粉分析，重建了腾格里沙漠南缘过程区全新世８０００￣３０００ａＢＰ期间的古气候演变序列。结果显示，（７９８０￣６８７０ａＢＰ气候变化特点为具振汇性的升温期，且尤以７４１０￣６８７０ａＢＰ最为明显；６８７０￣４６２０ａＢＰ为高温期，并可分为６６２０￣５７７０ａＢＰ温暖而     

Initial sequencing and comparative analysis of the mouse genome

The sequence of the mouse genome is a key informational tool for understanding the contents of the human genome and a key experimental tool for biomedical research. Here, we report the results of an international collaboration to produce a high-quality draft sequence of the mouse genome. We also present an initial comparative analysis of the mouse and human genomes, describing some of the insights that can be gleaned from the two sequences. We discuss topics including the analysis of the evolutionary forces shaping the size, structure and sequence of the genomes; the conservation of large-scale synteny across most of the genomes; the much lower extent of sequence orthology covering less than half of the genomes; the proportions of the genomes under selection; the number of protein-coding genes; the expansion of gene families related to reproduction and immunity; the evolution of proteins; and the identification of intraspecies polymorphism.     

Identification of the familial cylindromatosis tumour-suppressor gene

Familial cylindromatosis is an autosomal dominant genetic predisposition to multiple tumours of the skin appendages. The susceptibility gene (CYLD) has previously been localized to chromosome 16q and has the genetic attributes of a tumour-suppressor gene (recessive oncogene). Here we have identified CYLD by detecting germline mutations in 21 cylindromatosis families and somatic mutations in 1 sporadic and 5 familial cylindromas. All mutations predict truncation or absence of the encoded protein. CYLD encodes three cytoskeletal-associated-protein-glycine-conserved (CAP-GLY) domains, which are found in proteins that coordinate the attachment of organelles to microtubules. CYLD also has sequence homology to the catalytic domain of ubiquitin carboxy-terminal hydrolases (UCH).     

Collective synthesis of natural products by means of organocascade catalysis

Organic chemists are now able to synthesize small quantities of almost any known natural product, given sufficient time, resources and effort. However, translation of the academic successes in total synthesis to the large-scale construction of complex natural products and the development of large collections of biologically relevant molecules present significant challenges to synthetic chemists. Here we show that the application of two nature-inspired techniques, namely organocascade catalysis and collective natural product synthesis, can facilitate the preparation of useful quantities of a range of structurally diverse natural products from a common molecular scaffold. The power of this concept has been demonstrated through the expedient, asymmetric total syntheses of six well-known alkaloid natural products: strychnine, aspidospermidine, vincadifformine, akuammicine, kopsanone and kopsinine.     

纳粹为何造不出原子弹?

英美当局确实晓得了在一九四五年有造成原子弹的可能,当然是立刻要想知道,德国人有没有抢在他们的前面。希特勒的周期性地誇耀秘密武器,加重了他们的恐懼。于是美国人成立一个机构,叫做阿尔沙斯(Alsos),探听德国人在造些     

法共三巨頭

法国共产党是法国三大政党之一,也是欧洲(除了苏联)的最大最成功的共产党。战後的欧洲,在政治上可以说已普遍地向左倾。在这种情形之下,法国共产党的成败,不特可以决定法国的命运,也足以左右今後整个欧洲的政治动向。所以,法共的首脑人物和它的发展情形,是我们研究欧洲政治问题时所不能忽略的。