行星际空间中的磁重联事件

对１９７５￣１９８１年间Ｈｅｌｉｏｓ飞船的０．１８ｈ平均的磁场和等离子体测量予以了分析，发现行星际空间存在磁重联现象，通过重建方位角φ平面磁场位形的物理图象看到，时间尺度为天（ｄ）的磁重联事件－由一个介体（等离体团）和位于两侧的磁中性线（分隔区）构成，是行星际磁重联现象的一种重要表现形式，它可能源于日冕物质抛射事件或磁云，原理性的数值模拟再现了磁重联事件的基本观测特征。     

Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1

We report a genome-wide association study for open-angle glaucoma (OAG) blindness using a discovery cohort of 590 individuals with severe visual field loss (cases) and 3,956 controls. We identified associated loci at TMCO1 (rs4656461[G] odds ratio (OR) = 1.68, P = 6.1 × 10(-10)) and CDKN2B-AS1 (rs4977756[A] OR = 1.50, P = 4.7 × 10(-9)). We replicated these associations in an independent cohort of cases with advanced OAG (rs4656461 P = 0.010; rs4977756 P = 0.042) and two additional cohorts of less severe OAG (rs4656461 combined discovery and replication P = 6.00 × 10(-14), OR = 1.51, 95% CI 1.35-1.68; rs4977756 combined P = 1.35 × 10(-14), OR = 1.39, 95% CI 1.28-1.51). We show retinal expression of genes at both loci in human ocular tissues. We also show that CDKN2A and CDKN2B are upregulated in the retina of a rat model of glaucoma.