含区间参数的战场资源动态调度模型及算法

战场资源调度是作战指挥领域研究的热点.首先描述了战场资源调度问题,分析了战场资源动态调度需求,在此基础上建立了包含区间参数的战场资源动态调度模型.然后设计了三种不同的贪心策略,分别为基本贪心策略、双重贪心策略和一致贪心策略,提出了模型求解的混合贪心算法.最后结合联合作战算例进行了仿真验证,结果表明本文方法可行优越,能应用于不确定性的战场环境中.     

地方高师院校生物科学专业师范生创新实验能力的提升

当前在国家大力倡导"大众创业、万众创新"的新形势下,着力构建师范生的创新创业体系,提高创新实验能力,是提升学生科研素养和创新创业能力的必然要求,特别是对于地方本科师范院校而言显得尤为必要.通过分析地方高师院校生物科学专业师范生创新实验现状及原因,提出提升师范生创新实验能力的必要性和提升途径,为培养师范生综合能力,促进毕业生就业和深造提供重要参考.     

数学实验课程考核方式改革的探索与研究

对数学实验课程的考核方式改革进行深入分析和研究.指出传统考核方式的弊端,对考核方式进行了一系列改革和有益探索,增强了实践环节的考核,并对改革效果进行了客观评价.对需要完善改进的地方进行了探讨.     

本科生导师制下地理信息科学专业实践教学模式的研究

基于地理信息科学专业实践教学的特点,阐述了重庆师范大学本科生导师制下地理信息科学专业的实践教学模式及其现状,并从专业课程教学,科研项目,导师制评价和管理制度,面向专业竞赛的实践教学,本科研学团队和专业实习基地等方面论述了教改效果及改进措施.通过改革,地理信息科学专业学生的培养质量和竞争力得到了较大提升,符合我国地理信息产业长远和健康发展的需要.     

A review of three species of Hesperonoe (Annelida: Polynoidae) in Asia,with descriptions of two new species and a new record of Hesperonoe hwanghaiensis from Korea

A taxonomic review of three Asian species of Hesperonoe (Annelida: Polynoidae) is presented. Hesperonoe hwanghaiensis Uschakov and Wu, 1959 Uschakov PV, Wu B. 1959. [The polychaete worms of the families Phyllodocidae and Aphroditidae (Polychaeta, errantia) from the Yellow Sea]. Arch Inst Oceanol Sinica. 1:1–40, pls. I–X. (In Chinese and Russian). [Google Scholar] (type locality: Qingdao, China) is redescribed based on five specimens collected from an intertidal site in the Korean coast of the Yellow Sea, as a new record of this species from Korea, which is the only known habitat outside the type locality. Hesperonoe coreensis sp. nov. is described based on nine specimens collected from two intertidal sites in the Korean coast of the Yellow Sea, including the same site as the habitat of H. hwanghaiensis. Hesperonoe japonensis sp. nov. is described by re-examination of many specimens collected from eight intertidal sites and a subtidal one in Japan, which was previously misidentified as H. hwanghaiensis. The three species are clearly distinguishable from one another by the species-specific morphology of the macrotubercles (or marked ridges) on the surface of elytra. All of the three species seemed to be commensal with the burrowing mud shrimp Upogebia major in intertidal flats, except for an additional probable host of another upogebid shrimp Austinogebia narutensis for H. japonensis sp. nov. in a subtidal habitat. The morphological characteristics and host species of the three Asian species are compared with all of the other five congeners known from the North American Pacific and Arctic Sea.

http://www.zoobank.org/urn:lsid:zoobank.org:pub:51CB5C5B-0838-48AC-A0BA-8E63AA7628CB     

聚氨酯材料在生物医学中的研究进展

聚氨酯是一种合成的高分子化合物,有较好的机械性能、高弹性和理想的生物相容性,被广泛地用于生物医学领域。本文综述了聚氨酯在凝胶材料、弹性体材料、膜材料以及抗菌材料等方面的研究现状及应用前景。     

恶性肿瘤中IGFBP-rP1的抑癌基因作用机制及其可能的临床实用价值

胰岛素样生长因子结合蛋白相关蛋白1(IGFBP-rP1)是近年来恶性肿瘤的研究热点.本文主要综述IGFBP-rP1在恶性肿瘤中的抑癌基因作用机制及可能的临床实用价值.IGFBP-rP1在恶性肿瘤中的作用广泛涉及细胞的增殖、衰老、凋亡、分化、血管生成等多方面,研究指出IGFBP-rP1可缩短细胞增殖周期并影响非停泊性生长从而抑制增殖,降低致瘤能力;调节BRAF-MEKERK信号通路及pRB、HSP60等相关蛋白的表达从而影响衰老及凋亡;主要通过IGF依赖方式抑制血管生成;而且IGFBP-rP1表达下降跟肿瘤细胞分化程度降低有关.研究显示IGFBP-rP1有一定的临床实用价值,如其表达量跟恶性肿瘤的进展相关,低表达提示某些化疗药物抵抗,可提示预后.而在恶性肿瘤中特异性地上调IGFBP-rP1,可抑制肿瘤增殖及血管生成、诱导细胞衰老凋亡、提高肿瘤分化程度及化疗敏感性,具有治疗意义,但研究者们还在努力探究,争取早日找到一种临床有效的靶向IGFBP-rP1的基因治疗方法.     

体域网中基于特征组合的步态行为识别

物联网(internet of things,IOT)拥有无处不在的识别、传感和通信能力,体域网(body area network,BAN)属于物联网中和人体相关的领域,其应用广泛,可以在日常生活中对人们进行监测及提供帮助.行走是许多日常活动的基本环节,因而步态分析能为体域网应用提供重要的生理行为信息.现有的步态分析已取得一定的研究成果,但仍存在一些问题,例如大多数步态特征提取是对加速度信号进行6重以上的变换,使得特征达到了45维以上,最后需要通过降维或优化来简化特征,较为复杂.本文设计一种灵活便捷的数据采集系统,并利用小波变换、傅里叶变换和四分位差提取出加速度信号中比较简单、低维度但能反应运动特征的步态参数,之后通过模式识别算法进行步态行为识别验证.实验结果表明该系统使用方便,特征提取方法简单实用,识别精确度为97%,EER(equal error rate)最小可到0.9%.     

基于栅极信号的功率器件老化特征分析

本文研究栅极动态信号在功率器件故障预测上的应用.首先介绍了功率器件栅极动态信号反映的相关失效机制,并分析了栅极动态信号的老化特征及影响因素.提出了老化特征提取方法,选定动态过程时间,动态过程面积比率作为老化特征.使用降频错位采样的方法还原高频采样下计算的老化特征,降低利用动态信号进行故障预测的采样频率,以提高方法可行性.通过NASA公布的数据集进行实验验证,提取的老化特征明显,降频采样达到了预期效果.     

Metabolic engineering of Saccharomyces cerevisiae: a key cell factory platform for future biorefineries

Metabolic engineering is the enabling science of development of efficient cell factories for the production of fuels, chemicals, pharmaceuticals, and food ingredients through microbial fermentations. The yeast Saccharomyces cerevisiae is a key cell factory already used for the production of a wide range of industrial products, and here we review ongoing work, particularly in industry, on using this organism for the production of butanol, which can be used as biofuel, and isoprenoids, which can find a wide range of applications including as pharmaceuticals and as biodiesel. We also look into how engineering of yeast can lead to improved uptake of sugars that are present in biomass hydrolyzates, and hereby allow for utilization of biomass as feedstock in the production of fuels and chemicals employing S. cerevisiae. Finally, we discuss the perspectives of how technologies from systems biology and synthetic biology can be used to advance metabolic engineering of yeast.