对日ITO失败案例的分析与思考

日本的海外发包总额中有65%外包业务漉向我国,其中ITO占较大份额,由于中国企业对日ITO服务的经验不足,再加上项目经理大多数没有接受过专门对日ITO项目的正规训练以及专业知识和技巧的不足.造成较多的对日ITO项目的失败.调用一个对日ITO失败的典型案例,并分别在项目管理计划、项目任务和人力资源等方面进行分析.提出一些有益的启示,相信通过本案例的剖析,将有助于中国企业对日ITO的成功.     

2402例肿瘤化疗患者医院感染分析及预防措施

目的了解肿瘤化疗患者医院感染的现状,并探讨预防医院感染的相关措施.方法用回顾性调查方法对2 402例肿瘤化疗住院患者进行医院感染监测.结果有87例肿瘤化疗患者发生医院感染,感染率为3.62%;感染部位以呼吸道感染最高,占75.86%;肿瘤类型以肺恶性肿瘤居首,占51.72%;检出的病原菌中以革兰阴性杆菌检出最高,占65...     

急性脑梗死患者血清基质金属蛋白酶-9测定的临床意义

目的探讨血清基质金属蛋白酶-9(MMP-9)含量对急性血栓形成性脑梗死(ACI)患者并发出血性脑梗死(HI)、多脏器功能障碍(MODS)影响的临床意义。方法应用酶联免疫吸附试验双抗体夹心法(ELSA),对72例ACI患者及50例正常人血清MMP-9定量分析,对72例血清MMP-9含量不同程度增高ACI患者并发HI、MODS发生率进行比较分析。结果 ACI患者血清MMP-9含量病后6 h明显高于正常人(P0.01),病后2 d达最高,6 d恢复正常。ACI患者急性期血清MMP-9含量越高,HI、MODS发生率越高(P0.01)。结论 ACI患者急性期血清MMP-9含量增高是CI发生的重要的病理学基础,MMP-9含量与HI、MODS发生率呈正相关,提示检测MMP-9含量可为临床评估ACI的病情及预后提供有价值的依据。     

高校特殊学生信息数据库的模型构建

探讨了高校中特殊学生的现状,阐述了构建特殊学生信息数据库的必要性,提出了特殊学生信息数据库模型构建的方法。     

Mutations of the BRAF gene in human cancer

Cancers arise owing to the accumulation of mutations in critical genes that alter normal programmes of cell proliferation, differentiation and death. As the first stage of a systematic genome-wide screen for these genes, we have prioritized for analysis signalling pathways in which at least one gene is mutated in human cancer. The RAS RAF MEK ERK MAP kinase pathway mediates cellular responses to growth signals. RAS is mutated to an oncogenic form in about 15% of human cancer. The three RAF genes code for cytoplasmic serine/threonine kinases that are regulated by binding RAS. Here we report BRAF somatic missense mutations in 66% of malignant melanomas and at lower frequency in a wide range of human cancers. All mutations are within the kinase domain, with a single substitution (V599E) accounting for 80%. Mutated BRAF proteins have elevated kinase activity and are transforming in NIH3T3 cells. Furthermore, RAS function is not required for the growth of cancer cell lines with the V599E mutation. As BRAF is a serine/threonine kinase that is commonly activated by somatic point mutation in human cancer, it may provide new therapeutic opportunities in malignant melanoma.     

Rough set-based feature selection method

A new feature selection method is proposed based on the discern matrix in rough set in this paper. The main idea of this method is that the most effective feature, if used for classification, can distinguish the most number of samples belonging to different classes. Experiments are performed using this method to select relevant features for artificial datasets and real-world datasets. Results show that the selection method proposed can correctly select all the relevant features of artificial datasets and drastically reduce the number of features at the same time. In addition, when this method is used for the selection of classification features of real-world underwater targets,the number of classification features after selection drops to 20% of the original feature set, and the classification accuracy increases about 6% using dataset after feature selection.     

浅析工程量清单报价的优点及尚需探讨的问题

建筑工程招投标采用工程量清单模式,是适应与国际接轨和建立以市场形成工程造价机制的有效方法,也是我国工程造价体制改革的方向。工程量清单报价模式在推行中存在一些问题,政府有关部门和广大业内人士应重视这些问题,并采取相关措施,使工程量清单报价模式不断完善起来,使它沿着一条正确的道路健康发展。     

基于Prony算法的暂态电能质量扰动信号分析

针对电能质量扰动信号特性,提出了一种基于Prony方法的信号分解算法.该方法将指数变换的时频特性与暂态信号特性描述相结合,可以提供各种分量的特征指标,如频率、幅值、相位等,利用最小二乘法得到高精度的拟合,并对暂态电能质量扰动的仿真信号和实测信号进行了分析.结果表明,Prony算法在暂态电能质量扰动信号分析中,可提供有效、准确的分析结果.     

优化提取与分离海兔大脑神经节蛋白质组

蓝斑背肛海兔(Notarcus Leachii cirrosus Stimpson, NLCS)属于海洋软体动物. NLCS大脑神经节(cerebral ganglion, CG)富含高丰度的脂类物质,并干扰了三氯醋酸-丙酮法沉淀CG蛋白质. 本实验的目的是找到一种适合提取、分离海兔CG蛋白的方法. 经各种实验方法对比后,发现超速离心法能有效分离CG破碎液中的脂类化合物,提高双向凝胶电泳法分离BG蛋白质组的分辨率,大约可检测到450个蛋白质点.     

四光耦线性隔离放大器原理及实验研究

应用普通运算放大器LF353和普通光耦TLP521设计了一种新型线性隔离放大器．介绍了设计方案及其电路结构，并分析了其工作原理．实验结果验证了本设计方案的正确性．和同类放大器比较，该隔离放大器除了在性能上和集成模拟隔离放大器相接近外，还具有电路结构简单、易于实现、造价低廉等优点．