Chiglitazar monotherapy with sitagliptin as an active comparator in patients with type 2 diabetes:a randomized,double-blind,phase 3 trial(CMAS)

Chiglitazar(Carfloglitazar)is a novel peroxisome proliferator-activated receptor(PPAR)pan-agonist that has shown promising effects on glycemic control and lipid...     

Single-cell atlas of domestic pig cerebral cortex and hypothalamus

The brain of the domestic pig(Sus scrofa domesticus)has drawn considerable attention due to its high similarities to that of humans.However,the cellular composi...     

Optimization in the Migration Problem of Mobile Agents in Distributed Information Retrieval Systems

In this paper,we employ genetic algorithms to solve the migration problem (MP).We propose a new encoding scheme to represent trees,which is composed of two parts;the pre-ordered traversal sequence of tree vertices and the children number sequence of corresponding tree vertices.The proposed encoding scheme has the advantages of simplicity for encoding and decoding,ease for GA operations,and better equilibrium between exploration and exploitation.It is also adaptive in that,with few restrictions on the length of code,it can be freely lengthened or shortened according to the characteristics of the problem space.Furthermore,the encoding scheme is highly applicable to the degreeconstrained minimum spanning tree problem because it also contains the degree information of each node.The simulation results demonstrate the higher performance of our algorithm,with fast convergence to the optima or sub-optima on various problem sizes.Comparing with the binary string encoding of vertices,when the problem size is large,our algorithm runs remarkably faster with comparable search capability.     

天津市高新技术产业发展的特色及策略研究

系统的分析了天津市高新技术产业发展的现状及特色,并指出在发展过程中存在的约束条件和突出问题;在此基础上,提出了促进高新技术产业发展壮大,使天津从“生产型城市”向“创新型城市”转变的对策建议。     

Banach代数之间可加映射的若干性质

本文研究了Banach代数A与B之间某些可加映射f:A→B的性质。做为应用,得到f自动连续的几个代数条件。     

非线性退缩椭圆边值问题的多重解

1.问题与条件 在有界凸区域Q R~n(n≥2)上考虑问题:的多重解。其中aj_1(x)=aj_1(x)∈C°(Ω),且a_1(x)ξ_1ξ_j≥λ(x)|ξ|~2≥0(x)∈Ω 、ξ∈R~n),λ~(-1)(x)∈L~s(Ω)(s n)。∑=Ω,∑_3(=∑\∑_0)非空,∑_0=|x∈∑|n_1j(x)nj(x)。     

高校图书馆工作人员的信息素养

本文从图书馆发展需要与图书馆员自身发展的需要出发,论述了图书馆员应具备的信息素养,阐述了信息素养的内涵,分析了图书馆员信息素养的现状,并提出了培养图书馆员信息素养的举措。     

利用有机溶剂法快速纯化绿色荧光蛋白

介绍非色谱GFP纯化方法——有机溶剂纯化法．该方法在短时间内（30min）即可获得大量较高纯度（91．7％）,且荧光光谱特征不改变的GFP蛋白．纯化过程简单,无需昂贵的仪器和设备,适合绝大多数中小实验室使用．     

铁路基床翻浆冒泥病害成因的细观机理分析

基于朔黄铁路基床填料动力响应特性试验数据,建立PFC2D饱和粗颗粒土动三轴数值模型,选用线性黏结颗粒接触反映粗颗粒土的黏结特性,从细观力学和几何学角度研究翻浆冒泥病害形成的细观机理.结果表明:该数值模型能较好地反映粗颗粒土的动力响应特性.振动荷载通过改变土体颗粒与颗粒之间的接触荷载,破坏颗粒间的黏结键,形成自由颗粒和孔...