Optimization of PZT-Based Radio-Frequency Filters

Analytical solutions are presented for the wave equation for the electrode-piezoelectric-electrode sandwich structure in film bulk acoustic resonators (FBAR). The impedance for lead-zirconate-titanate (PZT)-based FBAR was derived using the proper boundary conditions and material parameters. A method is presented to adjust the resonant frequency based on the process and material properties. Ferroelectric-based radio-frequency filters were designed using FBARs. An accurate result is given for the filter impedance which can be used for other piezoelectric devices.     

一类拟线性波动方程的初边值问题

考虑一类拟线性波动方程的初边值问题,利用Galerkin方法和位势井方法讨论在混合边界条件下,在非线性阻尼与非线性源项相互干扰的情况下,强耗散与非线性因素之间的相互作用,分别得到了大初值和小初值能量情况下该问题整体广义解的存在性,惟一性及衰减性.     

基于齿面参数化表示的准双曲面齿轮的设计

为了能将拟合齿面模型用于准双曲面齿轮的设计，采用加工仿真方法获得了齿面上离散型值点坐标数据，完成了齿面非均匀有理B样条的曲面拟合．依据准双曲面齿轮的主动设计原理，解决了在已知齿面的NURBS表示、齿面接触迹线和传动比函数的条件下来设计未知齿面的关键技术，给出了基于离散化齿坯模型的加工仿真算法，将齿面的接触分析问题转化成一个优化问题，从而构建了齿面接触分析模型，并在其中采用啮合点法线与啮合点间连线之间的夹角趋于0的条件替代了法线重合条件，研究结果表明，齿面的NURBS表示模型可以作为面向准双曲面齿轮设计与制造过程的统一模型，以该模型为基础，可以完成齿面设计、数控机床刀位数据生成和坐标测量路径规划等一系列重要工作。     

掺Er~(3+)光纤放大器的增益特性

本文通过对掺Er~(2+)光纤放大器的小信号增益特性进行理论研究,导出了小信号增益公式,从而为设计和研究掺Er~(3+)光纤放大器提供了理论依据。     

结缕草种子生物学特性和质量检验技术的研究

详细观察了结缕草开花结实的生物学特性，发现江苏北部和山东南部结缕草最适采种期是６月下旬；建立了种子容重（ｘ）与饱满度（ｙ）的关系：ｙ＝０．３６ｘ—９４。提出的水选和风选方法能极大地提高种子饱满度。用２０％氢氧化钠处理２０ｍｉｎ或用２０％氢氧化钾处理４０ｍｉｎ，能破除种子休眠，使发芽整齐、迅速，发芽率成倍提高。用１％的四唑溶液染色２４ｈ，把胚全部染色的视为活种子，所测生活力与发芽率很接近。     

二向应力状态的矢量应力圆法

本文介绍二向应力状态的另一种解法——矢量应力圆法。该方法是以力的平衡方程为基础求力,并画出单元体所受外力的矢量图,从该图上可量出所求斜截面上力的大小和方向,从而应力的大小和方向即可求得。在某些情况下比用材料力学中的解析法或图解法更快些,且更易于想象。     

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

Retinoic-acid-inducible gene-I (RIG-I; also called DDX58) is a cytosolic viral RNA receptor that interacts with MAVS (also called VISA, IPS-1 or Cardif) to induce type I interferon-mediated host protective innate immunity against viral infection. Furthermore, members of the tripartite motif (TRIM) protein family, which contain a cluster of a RING-finger domain, a B box/coiled-coil domain and a SPRY domain, are involved in various cellular processes, including cell proliferation and antiviral activity. Here we report that the amino-terminal caspase recruitment domains (CARDs) of RIG-I undergo robust ubiquitination induced by TRIM25 in mammalian cells. The carboxy-terminal SPRY domain of TRIM25 interacts with the N-terminal CARDs of RIG-I; this interaction effectively delivers the Lys 63-linked ubiquitin moiety to the N-terminal CARDs of RIG-I, resulting in a marked increase in RIG-I downstream signalling activity. The Lys 172 residue of RIG-I is critical for efficient TRIM25-mediated ubiquitination and for MAVS binding, as well as the ability of RIG-I to induce antiviral signal transduction. Furthermore, gene targeting demonstrates that TRIM25 is essential not only for RIG-I ubiquitination but also for RIG-I-mediated interferon- production and antiviral activity in response to RNA virus infection. Thus, we demonstrate that TRIM25 E3 ubiquitin ligase induces the Lys 63-linked ubiquitination of RIG-I, which is crucial for the cytosolic RIG-I signalling pathway to elicit host antiviral innate immunity.     

基于VTS的稳健语音识别

为了进一步提高矢量Taylor级数(VTS)算法的模型补偿精度以及在噪声环境下的识别性能,提出将无监督聚类与VTS算法相结合。无监督聚类算法利用噪声模型之间的Kullback-Leibler距离将含噪语音段划分为若干个子段。然后针对各个子段分别进行一阶Taylor级数展开,并在此基础上逐段估计噪声参数和补偿声学模型。该算法结合一个中文数字串识别系统进行实验,在Babble噪声和Gauss白噪声环境下该算法的误识率相对传统的VTS算法分别下降了27.7%和17.8%。证明这种结合无监督聚类的分段VTS算法能够更加有效地将语音和噪声在倒谱域上的非线性混合模型用一阶线性模型来近似。     

Generation of a recombinant herpes simplex virus which can provide packaging function for recombinant adeno-associated virus

The generation of a recombinant HSV (rHSV) that can provide packaging function for rAAV production is described. A set of cosmids including cos48, cos28, cos6, cosl4 and cos56, which represents the HSV-1 genome was used for generation of this rHSV.Rep andcap genes of AAV-2 were inserted intoXba I site ofUL2 gene on cod, generating cos6rcΔUL2. After being digested withPac I, cos6-rcΔUL2 and the other 4 cosmids were cotransfected into BHK-21 cells. The recombinant virus HSV1-rc/ΔUL2 carryingrep andcap genes was generated due to the homologous recombination of the 5 cosmids. The results showed that the existence ofrep andcap genes on this rHSV was stable from passage to passage and the rHSV could support the packaging of rAAV either in cells transiently transfected with AAV vector or in stable cell line harboring AAV vector. Further modification of this rHSV and optimization of conditions involved in rAAV preparation may lead to a large-scale production of rAAV in the near future.     

In2O3-SnO2透红外导电膜的制备

透红外导电膜在夜视光学仪器中有着重要应用。我们在研制过程中推行QC,采用正交试验和电子计算机模拟,大大缩短了研制周期,成功地利用真空蒸镀法,制备了一批优质透红外导电膜,其光学和电学参数超过了国外同类产品。