Development of the CAS-IBB single-particle microbeam for localized irradiation of living cells

A single-particle microbeam facility has been constructed at the Key Laboratory of Ion Beam Bioengineering (LIBB), Chinese Academy of Sciences (CAS). The system was designed to deliver a defined numbers of hydrogen ions, produced by a van de Graaff accelerator, in an energy range of 2.0-3.0 MeV, into an area smaller than that of the nucleus of an individual living cell. The beam is collimated by a borosilicate glass capillary that forms the beam-line exit. An integrated computer program recognizes the cells and locates them one by one over the microbeam exit for irradiation. We present technical details of the CAS-LIBB microbeam facility, particularly on the collimator, hardware, control program, as well as cell irradiation protocols available. Various factors contributing to the targeting and positioning precision are discussed along with accuracy measurement results.     

P-RC APMP PULPING OF THE TRIPLOID OF POPULUS TOMENTOSA

The technology parameters of P-RC APMP process of the triploid of populus tomentosa and the the comparison of P-RC APMP with one and two stage f pretreatment were investigated in this paper. The results showed that in the chemical pretreatment the s that affected the pulp qualities. The charge of NaOH,y in the first stage of chemical pretreatment,was related to pulp strength. The charge of H2O2 tant pulp.In addition, the ratio of NaOH to H2O2 and the on of chemicals in the first and second stage of impregnation also affected the pulp qualities. The and two-stage P-RC APMP pulp illustrated that the ulp had better brightness and breaking length, lower light scatting coefficient and opacity.     

Effect of New O-Superfamily Conotoxin on Voltage-Activated Currents of Hippocampal Neurons

The effects of a new O-superfamily conotoxin, SO3, on sodium current (INa), transient A-type potassium currents (IA), and delayed rectified potassium currents (IK), were examined in cultured rat hippocampal neurons using the whole-cell patch clamp technique. Addition of SO3 caused a concentration-dependent, rapidly developing, and reversible inhibition of voltage-activated currents. The IC50 values for the blockage of INa, IA, and IK were calculated as 0.49, 33.9, and 7.6 μmol/L, respectively. The determined Hill coefficients were 1.7, 0.6, and 1.2, respectively. These results indicate that SO3 can selectively inhibit neuronal sodium and potassium currents.     

WATER-BASED BINDERS USED IN PROCESS FORMAKING AUTOMOBLE FILTER PAPER

INTRODUTIONThe paper used as the filtration medium for automotbile filters has been traditionally treated with alcohol solution of phenolic resins. This has been done to improve the paper's strength properties and allow it to be pleated in an accordion-like shape and to hold the shape when the paper composite is cured.[1]With the onset of greater concern for environmental quality, the filter manufactures have requested paper suppliers to provide a free or lower formaldehyde-containing impr…     

BIOCHEMICAL PULPING OF REED PRETREATED BY WHITE ROT FUNGI

INTRODUCTIONThe origin of biological pulping is natural degradation of lignin by microorganism, such as white rot fungi. Many researches have been carried out, on the biological degradation of the lignin in raw materials, mostly on woods. Those researches were mainly focused on microorganism pretreatment as a prior proceeding of the mechanical pulping, for the rare possibility of pulping directly with the pretreatment by a microorganism. A series of reports showed that microorganism pretr…     

STUDY ON THE ELEMENTAL CHLORINE FREE BLEACHING OF BAMBOO KRAFT PULP

1INTRODUCTIONChina is a country using the most variety of non-wood fiber raw material and is the largest country producing non-wood fiber pulp and paper in the world[1]. Bamboo is one kind of the main non-wood species for papermaking in China. Although the structure of raw materials for papermaking has being adjusted through increasing the proportion of wood pulp and by effectively utilizing waste paper source, non-wood species will still remain an important fiber resource[1,2].At present…     

A framework for personalized adaptive user interest prediction based on topic model and forgetting mechanism

User interest is not static and changes dynamically. In the scenario of a search engine, this paper presents a personalized adaptive user interest prediction framework. It represents user interest as a topic distribution, captures every change of user interest in the history, and uses the changes to predict future individual user interest dynamically. More specifically, it first uses a personalized user interest representation model to infer user interest from queries in the user’s history data using a topic model; then it presents a personalized user interest prediction model to capture the dynamic changes of user interest and to predict future user interest by leveraging the query submission time in the history data. Compared with the Interest Degree Multi-Stage Quantization Model, experiment results on an AOL Search Query Log query log show that our framework is more stable and effective in user interest prediction.     

高速水润滑止推轴承的滑移润滑性能研究

建立了多种具有不同滑移区域分布特征的推力瓦数学模型,在考虑流体边界滑移效应、扩展了经典Reynolds方程并设定合理边界条件的基础上,借助MATLAB软件对模型进行数值仿真求解,研究了滑移区域分布方式、面积占比及滑移长度对轴承动压润滑性能的影响。结果表明,在靠近流场入口处沿周向分布滑移区域能显著提升不同转速条件下的推力瓦面承载力;当滑移区域面积占瓦面面积比介于0.3~0.4且滑移长度为1000nm时,轴承推力瓦面具有最优动压润滑性能。     

十字型鸭翼子弹药控制系统研究

为解决子弹药的杀伤效能低的问题,提出了一种十字型鸭式子弹药并对其进行控制系统的分析与设计.针对子弹药不断旋转摆动的问题,分析了子弹药控制力的产生原理,提出一种周期平均控制力的方法,建立了旋转摆动子弹药数学模型.为验证子弹药的飞行稳定性,应用Matlab软件进行了无控飞行轨迹仿真,得出子弹药水平位移为450 m,攻角变化在0.4°以内,满足稳定性要求.由于子弹药控制通道间具有较强耦合作用,设计了一种特殊的前馈补偿法来对子弹药进行解耦,设计了PID控制器对子弹药控制效果进行了仿真,结果表明解耦后控制通道间的耦合效果基本消失.      

多停泊基地约束下港口拖轮作业的一体化调度优化

在分析拖轮调度问题基本性质的基础上,结合多处理器任务调度理论,构建了以拖轮总作业时间最小化为目标函数、考虑多停泊基地条件下的一体化调度优化模型;针对问题特点设计了混合模拟退火算法并对其进行求解;以二维实整数的方式作为解的表现形式,在初始解的生成过程中加入首艘可用拖轮的启发式规则,并运用三点交叉的方式产生新解.数值实例结果表明,所提出的算法收敛性较好,求解结果比现行调度规则所得结果的优化率提高了20%.对系统参数的分析表明:移泊作业所占比例和到港船舶类型对目标函数的影响较大;在拖轮配备中,总作业时间对拖轮配备情况具有极弱的敏感性,而在不同装卸作业时间下总作业时间的变化无规律性.