基于FLOWMASTER的制冷剂充注量对制冷系统性能影响的仿真研究

在分析制冷系统作用及基本原理的基础上,使用一维流体系统仿真软件FLOWMASTER的元件库建立了制冷系统仿真模型.用能量方程、动量方程和连续性方程联舍起来进行耦合求解,得到系统的温度和压力分布,进而得到流速及换热量等其它参数.在此基础上研究了制冷剂充注量对制冷系统性能的影响,得出了制冷量及COP（Coefficient of Performance,性能系数）随充注量变化的曲线,提出制冷剂的充注量要以制冷量达到设计要求时,系统的COP达到最大为原则.     

水肥高效利用灌排系统调控面临的问题研究

通过调查我国水肥利用的现状,指出我国农业水利中干旱缺水、非点源污染、水资源利用率低下和灌排系统不配套等问题,提出灌区水肥高效利用需深入研究的热点问题,对探讨水肥高效利用和灌排系统管理理论,指导我国灌排系统精量调控,以最少的水肥投入量获取最佳的灌区产量和经济及生态环境效益,具有重要意义.     

简单导联的非侵入便携式胎儿心电监护系统研究

提出并验证了一种简单导联方式实现的非侵入便携式胎儿心电监护仪的设计方案:以仪表放大器AD8220为核心,构建了母体胸导心电信号和腹壁混合信号的调理电路;通过AD7658实现A/D转换;然后将所得数字信号送入DSP芯片TMS320F28335,井通过USB通信模块CP2101将得到的心电信号数据传送到PC机。设计出了基于径向基函数的神经网络模块;提取出清晰的胎儿心电信号;调用绘图函数实现信号的实时显示。     

Genome-wide association studies of 14 agronomic traits in rice landraces

Uncovering the genetic basis of agronomic traits in crop landraces that have adapted to various agro-climatic conditions is important to world food security. Here we have identified ～ 3.6 million SNPs by sequencing 517 rice landraces and constructed a high-density haplotype map of the rice genome using a novel data-imputation method. We performed genome-wide association studies (GWAS) for 14 agronomic traits in the population of Oryza sativa indica subspecies. The loci identified through GWAS explained ～ 36% of the phenotypic variance, on average. The peak signals at six loci were tied closely to previously identified genes. This study provides a fundamental resource for rice genetics research and breeding, and demonstrates that an approach integrating second-generation genome sequencing and GWAS can be used as a powerful complementary strategy to classical biparental cross-mapping for dissecting complex traits in rice.     

韩国科技管理体制发展与演变探析

自20世纪60年代以来,韩国的科技发展取得了巨大的成就,其科技管理体制发挥了重要的作用.针对韩国科技管理体制形成与发展演变过程中经历的科技管理体系初步形成,以科技部为宏观管理决策部门的集中协调型管理体制,以及李明博政府对科技管理体制的重大调整等三个重要阶段进行了系统的分析研究,并对韩国科技管理体制的特点进行了总结和讨论.     

医疗服务供应链管理模型研究

在分析医疗服务特点的基础上,建立了基于信息平台的医疗服务供应链管理模型.其中,供应商、医院和患者通过信息平台进行有效沟通,进行需求管理、人力资源管理、医疗服务能力管理、供应商关系管理、医疗服务质量管理和医患关系管理,以及与卫生局、食品药品监督管理局、银行和政府等医疗服务供应链外部的联系.通过CR医院的实证分析,证明了基于信息平台的医疗服务供应链管理模型的有效性和实用性.     

煤层冲击倾向性试验及数值模拟

冲击地压是一种特殊的矿山动力现象,而冲击倾向性是煤岩体发生冲击地压的内在因素和必要条件.对松树镇煤矿主采煤层进行冲击倾向性试验,对冲击能量指数、弹性能量指数和动态破坏时间三个煤层冲击能量指标进行分析,得出煤层无冲击倾向性.但对开采煤层数值模拟,得出深部煤层顶部最大主应力值、顶板下沉较大,需要实施一定的防治措施.这为该矿防治冲击地压提供了科学依据.     

针对东方人黑色虹膜识别的光谱选择

本文以东方人黑色虹膜作为研究对象,进行两方面研究:1)对于单一光谱照明,找到某一个最适合东方人黑色虹膜的光谱段;2)对于多个光谱照明,确定东方人黑色虹膜所需要的光谱段数量.第一部分研究中,采用改进的卷积矩阵与频谱能量相结合的算法,对虹膜纹理质量进行评估;采用改进2-DGabor与1-DLog-Gabor相结合的编码方法,获得虹膜匹配性能的指标.实验显示:针对单一光谱照明,700nm对于东方人的黑色虹膜是最优的光谱段.第二部分研究中,采用改进multi-group(2D)2PCA算法,基于多光谱虹膜图像的最大不相关性进行层次聚类分析.实验显示:针对多个光谱照明,3个主聚类可以最好地描述从545nm到940nm的所有光谱段.以上研究在该领域内具有开拓性,解决了东方人黑色虹膜多光谱采集与识别的基础问题,为东方人黑色虹膜的多光谱融合提供了理论依据.     

Maize HapMap2 identifies extant variation from a genome in flux

Whereas breeders have exploited diversity in maize for yield improvements, there has been limited progress in using beneficial alleles in undomesticated varieties. Characterizing standing variation in this complex genome has been challenging, with only a small fraction of it described to date. Using a population genetics scoring model, we identified 55 million SNPs in 103 lines across pre-domestication and domesticated Zea mays varieties, including a representative from the sister genus Tripsacum. We find that structural variations are pervasive in the Z. mays genome and are enriched at loci associated with important traits. By investigating the drivers of genome size variation, we find that the larger Tripsacum genome can be explained by transposable element abundance rather than an allopolyploid origin. In contrast, intraspecies genome size variation seems to be controlled by chromosomal knob content. There is tremendous overlap in key gene content in maize and Tripsacum, suggesting that adaptations from Tripsacum (for example, perennialism and frost and drought tolerance) can likely be integrated into maize.     

Genome-wide association study of flowering time and grain yield traits in a worldwide collection of rice germplasm

A high-density haplotype map recently enabled a genome-wide association study (GWAS) in a population of indica subspecies of Chinese rice landraces. Here we extend this methodology to a larger and more diverse sample of 950 worldwide rice varieties, including the Oryza sativa indica and Oryza sativa japonica subspecies, to perform an additional GWAS. We identified a total of 32 new loci associated with flowering time and with ten grain-related traits, indicating that the larger sample increased the power to detect trait-associated variants using GWAS. To characterize various alleles and complex genetic variation, we developed an analytical framework for haplotype-based de novo assembly of the low-coverage sequencing data in rice. We identified candidate genes for 18 associated loci through detailed annotation. This study shows that the integrated approach of sequence-based GWAS and functional genome annotation has the potential to match complex traits to their causal polymorphisms in rice.