Isolation and purification of BVⅠ-2H from bee venom and analysis of its biological action

The medical use of bee venom for rheumatoid arthritis ( RA ) has a very long tradition. In this study, isolation and purification of polypeptides from bee venom were carried out on sephadex chromatography, heparin sepharose CL-6B chromatography and HPLC. Several fractions were extracted, and their effects on activation of splenocyte and THP-1 cell were studied. The inhibitory fraction was selected for further studies. Finally, BVⅠ-2H that the HPLC elution profiles was a single peak was isolated by C8 column. ESI- MS detection results showed that BVⅠ-2H was a fraction of bee venom, and the molecular weight of the major component was 644.8. BVⅠ-2H could inhibit ConA-induced splenocyte proliferation, IL-1 production and interfere with splenocyte cycle in mice. Moreover, BVⅠ-2H could inhibit PMA-induced TNFα production in THP-1 cells, which was due to its inhibitory effects on TNFα mRNA expression and protein phosphorylation of IκBα. Our studies indicated that BVⅠ-2H was one of the anti-inflammatory components of bee venom.     

可编程控制器调速器

本文以联合研制成功的水电站可编程控制调速器为对象，详细介绍其硬件与软件构成及工作原理。同时，对多种调节模式等方面也进行了一些探索。     

系统可靠性优化的离散多目标决策方法

工程实际中 ,人们往往在追求系统的可靠性达到最大的基础上 ,又追求系统的造价到达最小。另外 ,系统中单元的可靠性有时需从给定的离散集中选取。针对上述现象 ,提出了离散多目标决策方法 ,用于选取大型复杂系统中单元可靠性的最优值。算例表明所提出文方法有效     

工程设计单位小型局域网的组建与管理

介绍了小型局域网的特点，结构类型的选择，布线方法，操作系统的选择、安装与配置，安装防火墙和即时杀毒软件，并介绍了小型局域网的有效管理。     

作物高产性的光合碳同化生理限制因子分析

对影响作物高产的光合作用碳同化的生理限制因子进行了分析，提出内外因子结合考虑是提高作物的光合效率和产量的关键．     

多部图λκ_n(g)的G-设计,G为有1条悬边的4长圈

设λkn(g)是一个λ重完全n部图,G为一个不带孤立点的简单图,一个(λkn(g),G)-设计是将λkn(g)划分成边互不相交的子图,使得每一个子图都和G同构．在此基础上讨论了G为有1条悬边4长圈时多重完全多部图的G-设计的存在性．并给出其存在谱．     

Discovering Frequent Subtrees from XML Data Using Neural Networks

By rapid progress of network and storage technologies, a huge amount of electronic data such as Web pages and XML has been available on Internet. In this paper, we study a data-mining problem of discovering frequent ordered sub-trees in a large collection of XML data, where both of the patterns and the data are modeled by labeled ordered trees. We present an efficient algorithm of Ordered Subtree Miner （OSTMiner） based on two- layer neural networks with Hebb rule, that computes all ordered sub-trees appearing in a collection of XML trees with frequent above a user-specified threshold using a special structure EM-tree. In this algo- rithm, EM-tree is used as an extended merging tree to supply scheme information for efficient pruning and mining frequent sub-trees. Experiments results showed that OSTMiner has good response time and scales well.     

直觉在艺术中的作用

直觉是人类感知世界的能方和方式，是深层思维的一种形式，直觉感受因人而异。重直觉是中国传统思维方式的重要特点之一。本文仅从直觉在艺术中的作用展开说明。直觉能引发灵感，直觉在对艺术形式的把握、艺术欣赏方面都有不可估量的作用。     

交际过程中概念流利缺乏和多样性缺乏的隐喻性分析

二语学习者在交际过程中体现的概念流利的缺乏和多样性的缺乏分别由Danesi和文秋芳提出,对两者的解释都超出了语言范畴本身.本文基于概念隐喻和语法隐喻相关理论对这两种现象进行分析,认为当代隐喻理论的发展为这两种现象的解决提供了可能性,而且多样性的缺乏是概念流利缺乏的表现形式之一.     

工业CT重建图像中边缘梯度效应引起的高频伪影

为研究伪影对大型工件内部密度锐变区域高对比度微小缺陷检测的影响,从一个简单的轴对称断层模型出发,计算了边缘梯度效应引起的通过物体内部不同材料交界面处的射束的投影偏差。并研究采样相位的影响,探讨了由此偏差引起的重建图像中的高频伪影的表现形式。计算结果表明,高频伪影具有相当的强度,且具有与缺陷相似的表现形式,从而影响工业CT的检测能力。结合点扩散过程,高频伪影强度的计算为评估工业CT边缘处的缺陷检测能力提供了理论依据。