有摩擦的动力接触问题 模型、方法、试验和应用，第二版

摩擦接触用来传递力或耗散能量，较好地认识摩擦现象可以降低噪音和维护费用，增加机器的使用寿命，提高能源的效率。本书论述模拟有摩擦的动力接触问题的有效程序，这个程序可用于不同的实际问题，并用实验检验。     

Signal recognition particle contains a 7S RNA essential for protein translocation across the endoplasmic reticulum

In addition to its previously characterized, six different polypeptide components, signal recognition protein--which functions in protein translocation across and integration into the endoplasmic reticulum membrane--contains a 7S RNA molecule. The RNA is closely identified with the small cytoplasmic 7SL RNA and is required for both structural and functional properties of signal recognition protein--which we therefore rename signal recognition particle.     

经典数理物理学——动力学系统和场理论第三版

本书是关于经典数理物理学方面的专著，出版以来，一直受到物理及相关科学的重视，现已出版第三版。     

Vocalization during copulation behavior in greater horseshoe bats, Rhinolophus ferrumequinum

Vocal communication plays an important role for individual recognition and male-female interaction during mating in greater horseshoe bats,especially in respect to mate fidelity,which ensures that the bats can maintain a stable social organization.Few studies,however,have addressed the calling behavior during copulating in bats.Here,we initially report the copulation vocalizations and behaviors of both male and female greater horseshoe bats.During copulation,the male assumed a dorsal position and arched his back,arming around the female using his feet and thumbs.The male repeatedly produced very short constant frequency(SCF) syllables with high intensity and repetition rate(male 1:16.48±4.8 ms,male 2:17.79±4.03 ms) when he tried to insert the penis into the female,and then long syllables(male 1:42.08±12.67 ms,male 2:43.02±11.44 ms) after penile insertion.The female bats sometime refused the male bats in the early phase of copulations as emitting noise bursts and broad-band vocalizations,but kept silence during actual copulation.We also found that the SCF copulation calls of one male remained stable peak frequencies on different copulation days although its echolocation call frequency varied each day.Moreover,different male individuals maintained their own "private frequency" in the SCF copulation calls.Therefore,we predicted that the SCF copulation calls may serve as an indicator for female greater horseshoe bats to recognize the mating males in order to maintain mate fidelity because horseshoe bats exhibit sexual segregation before mating.Our results stipulate further studies on mating system and copulation strategies in polygynous bats.Such work may also aid in promoting the preservation of greater horseshoe bats.     

Evolutionary conservation of biogenesis of beta-barrel membrane proteins

The outer membranes of mitochondria and chloroplasts are distinguished by the presence of beta-barrel membrane proteins. The outer membrane of Gram-negative bacteria also harbours beta-barrel proteins. In mitochondria these proteins fulfil a variety of functions such as transport of small molecules (porin/VDAC), translocation of proteins (Tom40) and regulation of mitochondrial morphology (Mdm10). These proteins are encoded by the nucleus, synthesized in the cytosol, targeted to mitochondria as chaperone-bound species, recognized by the translocase of the outer membrane, and then inserted into the outer membrane where they assemble into functional oligomers. Whereas some knowledge has been accumulated on the pathways of insertion of proteins that span cellular membranes with alpha-helical segments, very little is known about how beta-barrel proteins are integrated into lipid bilayers and assembled into oligomeric structures. Here we describe a protein complex that is essential for the topogenesis of mitochondrial outer membrane beta-barrel proteins (TOB). We present evidence that important elements of the topogenesis of beta-barrel membrane proteins have been conserved during the evolution of mitochondria from endosymbiotic bacterial ancestors.     

Comparison of the mode of action of oxytocin and lysine-vasopressin on the isolated rat uterus

Zusammenfassung Ein der Rezeptorentheorie zugrunde liegender Vergleich der Dosis-Wirkungs-Beziehung zwischen Oxytocin und Lysine-vasopressin an der isolierten Rattengebärmutter hat gezeigt, dass während der Evolution die Oktapeptide der Neurohypophyse sowohl ihre Affinität für den Rezeptor als auch ihre maximale Aktivität bei Absättigung des Rezeptors, «intrinsic activity», verändert haben. Weiterhin wurde gefunden, dass Magnesium-Ionen in einer Konzentration von 0.5 mM nicht nur, wie bisher angenommen, die Affinität der Hormone, sondern auch ihre maximale Aktivität bei Absättigung des Rezeptors beeinflussen.     

Beethoven, a mouse model for dominant, progressive hearing loss DFNA36

Despite recent progress in identifying genes underlying deafness, there are still relatively few mouse models of specific forms of human deafness. Here we describe the phenotype of the Beethoven (Bth) mouse mutant and a missense mutation in Tmc1 (transmembrane cochlear-expressed gene 1). Progressive hearing loss (DFNA36) and profound congenital deafness (DFNB7/B11) are caused by dominant and recessive mutations of the human ortholog, TMC1 (ref. 1), for which Bth and deafness (dn) are mouse models, respectively.