北部湾大型海藻资源研究及应用展望

对北部湾大型海藻物种多样性、地理分布、资源研究成果、研究现状以及开发利用等进行总结和分析,发现北部湾在大型海藻资源调查、开发利用和生态修复等方面还有巨大的研究空间,提出大力发展海藻生态养殖业,加大对大型海藻科研的支持和投入,扶助海藻产业链建设的观点,以期为北部湾海洋经济持续发展提供参考。     

Research progress in ZnO single-crystal: growth,scientific understanding,and device applications

Zinc oxide, a wide band-gap semiconductor, has shown extensive potential applications in high-efficiency semiconductor photoelectronic devices, semiconductor photocatalysis, and diluted magnetic semiconductors. Due to the undisputed lattice integrity, ZnO single crystals are essential for the fabrication of high-quality ZnO-based photoelectronic devices, and also believed to be ideal research subjects for understanding the underlying mechanisms of semiconductor photocatalysis and diluted magnetic semiconductors. This review, which is organized in two main parts, introduces the recent progress in growth, basic characterization, and device development of ZnO single crystals, and some related works in our group. The first part begins from the growth of ZnO single crystal, and summarizes the fundamental and applied investigations based on ZnO single crystals. These works are composed of the fabrication of homoepitaxial ZnO-based photoelectronic devices, the research on the photocatalysis mechanism, and dilute magnetic mechanism. The second part describes the fabrication of highly thermostable n-type ZnO with high mobility and high electron concentration through intentional doping. More importantly, in this part, a conceptual approach for fabricating highly thermostable p-type ZnO materials with high mobility through an integrated three-step treatment is proposed on the basis of the preliminary research.     

Dynamic analysis of DNA damage induced miRNAs in colon cancer cells

It is known that microRNAs （miRNAs） expression profile shows substantial changes in cells under DNA damage. Here, we did miRNA microarray and quantitative real-time PCR to comprehensively identify the differentially expressed miRNAs in colon cancer cell lines HCT116 p53＋/＋ and HCT116 p53-/-. Cluster analysis revealed a panel of differentially expressed miRNAs which are regulated by p53 and/or UV-C induced DNA damage. These altered miRNAs tend to be located in chromosomes 13, X and 17. Moreover, pathways enrichment analysis estimated that MAPK pathway, focal adheren pathway, p53 pathway and Wnt pathway were mediated by these miRNAs to exert their functions in DNA damage response. Additionally, we found that miR- 320a, one of the UV-C induced miRNAs, play a role in protecting cells from DNA damage. Taken together, our results show that miRNAs are dynamic regulated in p53- dependent or -independent manners in different cell contexts and different situations following DNA damage.     

Stable silver nanoparticles–aptamer bioconjugates for cellular prion protein imaging

Combining the unique optical properties of metal nanoparticles and the specific recognition of aptamer,aptamer–nanoparticle conjugates have been extensively used in a wide range of applications,particularly multifunctional nanoparticles for cell detection and molecular imaging.Conventional conjugates prepared by chemisorption of monothiol-modified oligonucleotides onto nanoparticle surfaces suffer from a lack of stability when exposed to a variety of small molecules.If silver is used in place of gold,then this lack of stability is even more pronounced.In this study,we reported here the effective and facile strategy of preparing stable silver nanoparticle–aptamer conjugates by in situ generation of strong metal affinity capping ligands,dithiocarbamates modified anti-prion protein aptamer.The conjugates produced are stable and can withstand NaCl concentration at0.25 mol/L.Meanwhile,they could be applied in the cellular prion protein imaging successfully.     

金属离子负载树脂对水中氨氮的吸附特征

研究了金属离子负载树脂对水中氨氮的吸附特征.金属离子负载树脂对氨氮的吸附等温线表明,温度的升高有利于吸附,且吸附等温线都符合Langmuir模型.两种金属离子负载树脂对氨氮的吸附都符合准二级动力学方程.     

广西大瑶山野生绞股蓝六种无机元素的测定

目的：对广西大瑶山野生绞股蓝茎、叶中的六种无机元素进行测定.方法：采用湿法消化法和原子吸收法进行研究.结果：广西大瑶山野生绞股蓝茎、叶中六种元素含量差异较大,叶中的含量明显高于茎中的含量,所测的六种元素的含量依次为：Ca〉Mg〉Fe〉Mn〉Zn〉Cu.结论：广西大瑶山野生绞股蓝六种无机元素的含量较为丰富,可以满足人体的需要,本研究为探讨无机元素与绞股蓝药理作用之间的关系提供了可靠的依据,为绞股蓝药物开发提供了方向.     

A novel GEL-OHA/HAp bone substitute

Self-crosslinked gelatin-oxidized hyaluronic acid/ hydroxyapatite (GEL-OHA/HAp) composite bone substitute was successfully prepared with a novel in situ precipitation method without using any toxic chemical cross-linkers, and its characterizations, including elemental composition, surface morphology, crystallinity, and structure of crystalline phase, were carried out. In order to evaluate its corresponding performances, comparisons with glutaraldehyde crosslinked gelatin/hydroxyapatite (GEL-Glu/ HAp) composite were made in detail. The results indicate that nano-HAp crystallites are homogeneously dispersed in both GEL-OHA/HAp and GEL-Glu/HAp composites, and the HAp crystallites in the former take larger particle size than those in the latter. Mechanical property tests show the acceptable mechanical strength at high strain of GEL-OHA/HAp composite. Study of in vitro degradation and swelling demonstrate that the two composites have similar degradation rate and water absorption capability. By in vitro cell culture, it has been found out that the cells on the GEL-OHA/HAp composite show higher proliferative potential than the cells on the GEL-Glu/HAp composite. Compared with GEL-Glu/HAp composite, GEL-OHA/HAp composite provides an excellent strategy for preparation of non-toxic bone substitute with acceptable corresponding properties.     

Generalized inverse eigenvalue problem for (<Emphasis Type="Italic">P</Emphasis>,<Emphasis Type="Italic">Q</Emphasis>)-conjugate matrices and the associated approximation problem

In this paper, the generalized inverse eigenvalue problem for the (P,Q)-conjugate matrices and the associated approximation problem are discussed by using generalized singular value decomposition (GSVD). Moreover, the least residual problem of the above generalized inverse eigenvalue problem is studied by using the canonical correlation decomposition (CCD). The solutions to these problems are derived. Some numerical examples are given to illustrate the main results.     

A star-style trust model with the ability of data recovery for trusted computing platform

Varieties of trusted computing products usually follow the mechanism of liner-style chain of trust according to the specifications of TCG. The distinct advantage is that the compatibility with the existing computing platform is preferable, while the shortcomings are obvious simultaneously. A new star-style trust model with the ability of data recovery is proposed in this paper. The model can enhance the hardware-based root of trust in platform measurement, reduce the loss of trust during transfer process, extend the border of trust flexibly, and have the ability of data backup and recovery. The security and reliability of system is much more improved. It is proved that the star-style trust model is much better than the liner-style trust model in trust transfer and boundary extending etc. using formal methods in this paper. We illuminate the design and implementation of a kind of trusted PDA acting on star-style trust model.     

Attribute level lineage in uncertain data with dependencies

In uncertain data management, lineages are often used for probability computation of result tuples. However, most of existing works focus on tuple level lineage, which results in imprecise data derivation. Besides, correlations among attributes cannot be captured. In this paper, for base tuples with multiple uncertain attributes, we define attribute level annotation to annotate each attribute. Utilizing these annotations to generate lineages of result tuples can realize more precise derivation. Simultaneously, they can be used for dependency graph construction. Utilizing dependency graph, we can represent not only constraints on schemas but also correlations among attributes. Combining the dependency graph and attribute level lineage, we can correctly compute probabilities of result tuples and precisely derivate data. In experiments, comparing lineage on tuple level and attribute level, it shows that our method has advantages on derivation precision and storage cost.