基于非对称交叉开关的高阶路由器设计

对非对称交叉开关的吞吐率进行了理论分析和模拟测试,得出非对称交叉开关中排头兵效应的影响非常弱,几乎可以忽略.在此基础上,提出了一种基于非对称交叉开关的高阶路由器交换结构,即层次式非对称交叉开关结构设计方法,同时,给出了该交换结构的瓦片化微结构.结果表明,该结构可以获得很高的吞吐率.     

剑杆织机打纬引纬系统结构尺寸误差对打纬和引纬运动的影响

本文用矩阵法分析了剑杆织机系统结构尺寸误差对打纬和剑头引纬运动的影响,建立了打纬和剑头运动两者的误差与系统各结构参数误差之间关系的矩阵方程。以1511普及型剑杆织机为实例进行了分析计算,得到了较满意的结果。本文所述及的方法具有一般性。     

钢筋混凝土有边框剪力墙抗剪因素分析

依据试验资料论述钢筋混凝土有边框剪力墙的工作机理和强度性能,综合分析剪跨比、配筋率、混凝土强度等因素对剪力墙抗剪强度的影响。     

非均匀地表的湍流通量和掺混高度

叙述了掺混高度的概念及运用。利用大涡模拟作为手段,研究了地表平坦但地表热通量非均匀情况下的掺混高度。考察了地表热通量非均匀性尺度、风速以及非均匀性强度对掺混高度的影响,发现掺混高度是否存在以及高度受非均匀尺度和风速大小的影响非常明显,受非均匀性强度的影响不明显。若规定掺混高度出现在垂直湍流热通量水平涨落的标准差减为地表感热通量标准差5％的高度,这时掺混高度可以拟合为：Z_b = 1/C_wm * w'θ'_sfc/Θ₀ * L^a_hetero/U^b,其中a=1.266,b=0.854,C_wm=3.205×10^-3。     

海藻多糖片中多糖含量测定

建立了一种测定海藻多糖片中多糖含量的苯酚-硫酸法.以葡萄糖作为标准品,在490nm波长处测定吸光度,在浓度20.16～100.80μg/mL之间线性关系良好(r=0.998 2),平均回收率为99.55%,相对标准偏差(RSD)为0.56%.本方法简单、准确,可用于海藻多糖片中多糖含量的检测.     

Application of EEG multipole model in the diagnosis of Alzheimer''''s disease

In order to find the electroencephalogram （EEG） characteristic parameters typical of Alzheimer＇s disease （AD） and explore an effective diagnostic method, a new mobile current multipole model was proposed to simulate the AD patient＇s cortical dipole source activities. The indicators of goodness of fit （GOF） and DtononD （DD） were calculated from EEG samples to evaluate the performance of this model. Relevant results showed that this multipole model with higher GOFvalues and larger DD change well fitted the pathological electrical activities of cortical neurons aroused by AD＇s extended sulcus and gyrus in the cerebral cortex. Meanwhile, the products of DD mean ＆ standard variance were found in a clear linear correlation with the diagnostic data of mini-mental state examination （MMSE） used in AD clinics. Furthermore, by tracing this multipole model＇s indicators in typical patients and contrasting with the functional magnetic resonance image （fMRI） as AD progressed, we suggested that the DD index may be suitable for monitoring the AD developments as a new diagnostic parameter.     

棉花种子变温冷害的初步研究

以棉花种子新陆早１号为材料，研究了２０～１２℃、２０～８℃、２０～２℃、１６～８℃、１６～２℃、１２～５℃六种不同变温分别处理１天、２天、３天、４天、５天后的发芽率，初步认清了棉花种子变温与冷害的关系．结果表明，变温的幅度及低温的程度是决定冷害的主要因素，低变温的持续时间也是影响冷害的主要因素．     

隧道代理的负载均衡问题研究

隧道代理是IPv4-IPv6过渡过程中的重要技术,分布式部署隧道代理有利于提高系统的可靠性.为了解决隧道代理分布式部署面临的负载均衡问题,本文从调度者,参数和调度算法3个方面研究了隧道代理的负载均衡问题,并结合最少利用率算法和加权叫算法,提出了一种包含简单预测机制和过载预警机制的负载均衡算法.仿真实验的结果表明,所提出的算法在突发用户接入、突发初始负载和预防过载的方面,优于现有的负载均衡算法,适应于隧道代理系统的分布式运行实践.     

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

The recycling of the amyloid precursor protein (APP) from the cell surface via the endocytic pathways plays a key role in the generation of amyloid beta peptide (Abeta) in Alzheimer disease. We report here that inherited variants in the SORL1 neuronal sorting receptor are associated with late-onset Alzheimer disease. These variants, which occur in at least two different clusters of intronic sequences within the SORL1 gene (also known as LR11 or SORLA) may regulate tissue-specific expression of SORL1. We also show that SORL1 directs trafficking of APP into recycling pathways and that when SORL1 is underexpressed, APP is sorted into Abeta-generating compartments. These data suggest that inherited or acquired changes in SORL1 expression or function are mechanistically involved in causing Alzheimer disease.