全文获取类型
收费全文 | 65027篇 |
免费 | 1024篇 |
国内免费 | 1490篇 |
专业分类
系统科学 | 2661篇 |
丛书文集 | 686篇 |
教育与普及 | 770篇 |
理论与方法论 | 609篇 |
现状及发展 | 29249篇 |
研究方法 | 92篇 |
综合类 | 31286篇 |
自然研究 | 2188篇 |
出版年
2016年 | 654篇 |
2015年 | 779篇 |
2014年 | 974篇 |
2013年 | 1399篇 |
2012年 | 1090篇 |
2011年 | 3676篇 |
2010年 | 1310篇 |
2009年 | 1670篇 |
2008年 | 1581篇 |
2007年 | 1623篇 |
2006年 | 1503篇 |
2005年 | 1707篇 |
2004年 | 3258篇 |
2003年 | 2604篇 |
2002年 | 2079篇 |
2001年 | 1557篇 |
2000年 | 972篇 |
1999年 | 1465篇 |
1998年 | 1473篇 |
1997年 | 1557篇 |
1996年 | 1059篇 |
1995年 | 964篇 |
1994年 | 1177篇 |
1993年 | 1489篇 |
1992年 | 1271篇 |
1991年 | 1186篇 |
1990年 | 1076篇 |
1989年 | 855篇 |
1988年 | 751篇 |
1987年 | 686篇 |
1986年 | 669篇 |
1985年 | 711篇 |
1984年 | 640篇 |
1982年 | 710篇 |
1981年 | 756篇 |
1980年 | 815篇 |
1979年 | 1048篇 |
1978年 | 1002篇 |
1977年 | 1005篇 |
1976年 | 911篇 |
1975年 | 871篇 |
1974年 | 598篇 |
1973年 | 941篇 |
1972年 | 1011篇 |
1971年 | 943篇 |
1970年 | 910篇 |
1969年 | 902篇 |
1968年 | 863篇 |
1967年 | 722篇 |
1966年 | 578篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
481.
B. Streit 《Cellular and molecular life sciences : CMLS》1995,51(5):425-436
The goal of this article is twofold: 1) It aims at providing an overview on some major results obtained from energy flow studies in individuals, populations, and communities, and 2) it will also focus on major mechanisms explaining community structures. The basis for any biological community to survive and establish a certain population density is on the one hand energy fixation by primary producers together with adequate nutrient supply and the transfer of energy between trophic levels (bottom-up effect). On the other hand, predator pressures may strongly control prey population densities one or more trophic levels below (top-down effect). Other interpopulation effects include competition, chemical interactions and evolutionary genetic processes, which further interact and result in the specific structuring of any community with respect to species composition and population sizes. 相似文献
482.
Thrombospondin (TSP) is a multifunctional glycoprotein which is synthesised by several cell types including osteoblasts, and incorporated into the extracellular matrix (ECM) of these cells. The function and regulation of TSP in bone is not clear. In this study, using a long term culture model of human osteoblast-like cells, we examined the distribution of TSP in the ECM and its modulation by added estradiol. In this model the osteoblast-like cells form a regular multilayer which continues to increase in depth up to 50 days post confluence. In the ECM of these cultures and in 19-week fetal bone, the bone markers osteocalcin and alkaline phosphatase were diffusely distributed in the matrix. In contrast, labelling for TSP was concentrated, confined to the banded collagen and its immediately adjacent ECM. This pattern of labelling resembled that of the growth factors transforming growth factor-I (TGF), and insulin-like growth factor-I (IGF-I), with which TSP label co-localised. Labelling intensities were comparable between fetal bone and the in vitro material for TSP, TGF and IGF-I. TSP label was present by 10 days post confluence, reached a maximum by 20 days, and declined slowly thereafter, a time course which was similar to that of IGF-I. Incubation of osteoblast-like cell cultures with 17 estradiol resulted in an increase in multilayer depth and a maximal 3-fold increase in TSP labeling at 30 days as well as approximately 2-fold increases for TGF and IGF-I. The dose-response relationship for these responses to estradiol treatment was biphasic with maximal increases at 10–10 M–10–11 M of added estradiol. Treatment with 17 estradiol produced labelling intensities that were not significantly different from controls. Studies with other cell types have suggested that TSP may be involved in modulation of growth factor activity. The similarities between TSP, TGF and IGF-I, in terms of their distribution and regulation by 17 estradiol treatment, may indicate a role for TSP in modulating bone cell proliferation and function through interaction with local growth factors. 相似文献
483.
G. Bergström A. -B. Wassgren O. Anderbrant J. Fägerhag H. Edlund E. Hedenström H. -E. Högberg C. Geri M. A. Auger M. Varama B. S. Hansson J. Löfqvist 《Cellular and molecular life sciences : CMLS》1995,51(4):370-380
The main component of the sex pheromone secretion of femaleDiprion pini L. (Hymenoptera: Diprionidae) from insects collected both in Finland and in France has been identified as athreo-3,7-dimethyl-2-tridecanol (8 ng per female) stereoisomer by GC-MS and synthesis. The secretion also contains lower and higher homologues in small amounts (1–4% of the main component). Combined gas chromatographic-electroantennographic detection showed activity in both natural and esterified extracts (acetates and propionates); the esters of the main component gave the largest responses. The acetates and propionates of the eight stereoisomers of 3,7-dimethyl-2-tridecanol were synthesized from enantiomerically highly enriched (>99% ee) building blocks. The stereochemistry of the main component was established to be (2S,3R,7R)-3,7-dimethyl-2-tridecanol by GC analysis of the natural material. It was purified by liquid chromatography prior to the GC analysis of both its pentafluorobenzoates and its isopropylcarbamates on a non-chiral polar column (ECD) and a chiral column (NPD), respectively. Field tests demonstrated that both the acetate and propionate of the main component (100 g of each applied on cotton roll dispensers) were active in attracting males, with or without the presence of several of the minor compounds. Experiments with smaller amounts of the acetate and the propionate (1 g in France and 50 g in Finland) demonstrated that the propionate was more active than the acetate, and that it also caught more males than a blend of the two compounds. 相似文献
484.
J. Martín-Gil F. J. Martín-Gil G. Delibes-de-Castro P. Zapatero-Magdaleno F. J. Sarabia-Herrero 《Cellular and molecular life sciences : CMLS》1995,51(8):759-761
Vermillion has been shown to be useful in preserving human bones from 5000 years ago. Remarkably well-preserved human bones have been found in the dolmenic burial La Velilla in Osorno (Palencia, Spain), carefully covered by pulverized cinnabar (vermillion) which ensured their preservation even in non-favorable climatic conditions. We believe the red powder was deliberately deposited for preservative use because no cinnabar mine is to be found within 160 km, because of the large amount (hundreds of kilograms) used, and because its composition, red mercuric sulphide, is similar to that of preparations used in technical embalming. This finding pushes back the data of the use of mercury ore for preservation by four millennia in South America, and by at least one millennium in the Old World. Chemical and thermal analyses of vermillion in La Velilla have demonstrated its great purity and shown that the cinnabar was pulverized and washed (but not heated), producing a bright red-orange tone. 相似文献
485.
X. Wang C. A. Lessman D. B. Taylor T. K. Gartner 《Cellular and molecular life sciences : CMLS》1995,51(11):1097-1102
Gastrulation is characterized by dramatic cell migration which is thought to require the interaction of cell adhesion molecules with extracellular molecules. We have tested two novel peptides, a fibronectin peptide and a fibronectin receptor peptide, for their effects on gastrulation of the leopard frogRana pipiens. The fibronectin peptide DRVPHSRNSIT corresponds to residues 1373–1383 of the cell-binding domain of fibronectin; the receptor peptide DLYYLMDL corresponds to residues 124–131 of 1 subunit of a variety of integrins including 51. Either of these peptides significantly inhibited gastrulation after being microinjected into mid-blastulae. These results indicate that these sequences may correspond to the ligand/receptor interaction sites of fibronectin and its receptor(s). 相似文献
486.
提出一种可用于机类和非机类使用的金属工艺学试题库软件系统。该系统具有较强的管理与维护功能,能自动成卷,接口技术简单,可采用不同软件排版、输出。具有快速处理试卷表格题与图形题的能力。 相似文献
487.
The INDSCAL individual differences scaling model is extended by assuming dimensions specific to each stimulus or other object, as well as dimensions common to all stimuli or objects. An alternating maximum likelihood procedure is used to seek maximum likelihood estimates of all parameters of this EXSCAL (Extended INDSCAL) model, including parameters of monotone splines assumed in a quasi-nonmetric approach. The rationale for and numerical details of this approach are described and discussed, and the resulting EXSCAL method is illustrated on some data on perception of musical timbres. 相似文献
488.
本文是关于非线性模拟电路故障诊断的测试点选择问题的研究,在本文提出的关于诊断方程的雅可比矩阵的物几乎处处恒等这一概念的基础上,研究了非线性情况下诊断方程的形式及其可测性问题。 相似文献
489.
针对机载雷达面临的杂波抑制问题,在考虑阵元误差、通道误差和杂波起伏等误差因素对杂波特性影响的基础上,建立了机载MIMO雷达杂波数学模型,提出了一种基于MIMO雷达体制下的空时自适应新方法——M3-CAP方法。对接收信号进行时域滤波,选取被检测通道与其2个相邻通道为一组,进行自适应处理。该方法通过MIMO技术与3-CAP方法的有效结合,将波形分集的优势扩展到3-CAP方法中,显著提高了雷达系统自由度和杂波协方差矩阵估计精度。通过对不同雷达体制以及不同误差条件下杂波抑制性能的分析比较,结果表明:提出的M3-CAP方法的杂波抑制性能明显优于JDL-GMB、改进的JDL、3-CAP等方法。 相似文献
490.