The structure-based design of zinc finger nucleases can facilitate genomic editing

A recent study of significant research value carried out at the State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou,     

基于结构光立体视觉的激光再制造工件的测量

为了实现激光再制造工件的快速准确测量,提出了1套与激光再制造机器人耦合的视觉系统.该视觉系统由2个摄像机、1个激光投射器和计算机组成.摄像机和激光投射器组成扫描测头,由6自由度机器人手持实现多视角扫描.并自动完成数据拼接,消除‘死角'.首先,通过MATLAB编程完成系统标定,分别标定出单目摄像机内外参数矩阵,双目相机关...     

基于浙江省台风灾害保险数据的农村住房易损性评价

利用浙江省农业政策性保险试点项目中的农村住房保险及理赔数据,定量分析了浙江省2007年圣帕、韦帕及罗莎3场台风灾害期间农村住房投保金额、赔付金额、保额损失率的分县汇总数据,以及与这3场台风的极大风速、过程降水量等致灾因子强度的定量关系.研究发现,浙江省农村住房的台风灾害保险金额损失率,其对数与过程降雨量有着很好的线性相关关系.依据这一关系,建立了浙江省农村住房台风易损性方程并给出相关参数.     

金洞森林旅游开发的前景及效益分析

文章从发展生态旅游入手,结合当前森林旅游形势的需要,从社会基础、自然条件、区位优势与资源优势进行分析,以突出金洞的本土特色,提出合理的建设原则,并设计相应的森林旅游项目,从实际出发提出可行的开发形式与管理办法,通过效益分析得出开发森林旅游的可行性结论。     

裂解汽油一段加氢催化剂的研究进展

乙烯工业副产物裂解汽油是芳烃抽提的重要原料,加氢精制是处理裂解汽油最有效、最经济的方法.文章主要介绍了裂解汽油一段加氢钯系、镍系催化荆的研究进展,同时指出裂解汽油一段加氢催化剂在工业应用上存在的问题.     

一类人口发展方程解的存在性和收敛性的研究

用线性算子的理论将人口发展的偏微分方程模型转化为抽象的Cauchy问题,并用泛函分析中的C0半群理论来研究该系统解的存在性和收敛性.     

多星载光学传感器系统误差极大似然配准算法

针对低轨星座协同探测弹道目标过程中存在系统误差的问题,提出多星载光学传感器系统误差极大似然配准（maximum likehood registration,MLR）算法。通过一阶Taylor近似对非线性量测转换线性化,推导出目标状态的误差协方差与卫星轨道定向、姿态角测量和传感器测量等随机误差的关系,并基于视线交叉获得观测在状态空间中的近似投影,从而将MLR算法扩展到低轨星座多光学传感器的误差配准。通过引入各类测量误差的先验信息对目标状态的误差协方差进行修正,利用期望极大化迭代,实现了对系统误差的无偏有效估计及目标轨迹的融合估计。仿真验证了所提算法的有效性,且配准性能优越。     

Study on the application of active balancing device to solve the vibration problem for the rotor with bending fault

The rotor with bending faults that occurrs on the rotating machinery usually vibrates seriously. This paper investigates to apply the active balancing device on a flexible rotor with bending faults to solve the vibration problem. Two problems are studied by finite element method firstly： Where the balance actuator is fixed on the shaft and how much the balancing capacity of the active balancing device is needed. The experiment is then carried out on the test rig, which consists of a flexible rotor with bending faults. The test results indicate that the bending rotor peak vibration response can be decreased from 550~m to 40~tm below by using the active balancing device. The peak vibration response decreases approximately by 93 %. The synchronous vibration due to the rotor bending faults can be controlled effectively by using ac- tive balancing device. The active balancing device is especially adapted to solve the problem caused by thermal distortion with time-variation and randomness, which is varied with working conditions, thus it has good practical value in practice.     

A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia

Non-obstructive azoospermia (NOA) is one of the most severe forms of male infertility. Its pathophysiology is largely unknown, and few genetic influences have been defined. To identify common variants contributing to NOA in Han Chinese men, we performed a three-stage genome-wide association study of 2,927 individuals with NOA and 5,734 controls. The combined analyses identified significant (P < 5.0 × 10(-8)) associations between NOA risk and common variants near PRMT6 (rs12097821 at 1p13.3: odds ratio (OR) = 1.25, P = 5.7 × 10(-10)), PEX10 (rs2477686 at 1p36.32: OR = 1.39, P = 5.7 × 10(-12)) and SOX5 (rs10842262 at 12p12.1: OR = 1.23, P = 2.3 × 10(-9)). These findings implicate genetic variants at 1p13.3, 1p36.32 and 12p12.1 in the etiology of NOA in Han Chinese men.