Characterization of the Antigenicity and Immunogenicity of the Escherichia Coli Produced RNase Domain of the Classical Swine Fever Virus Glycoprotein E~(rns)

Erns is a highly glycosylated envelope protein of classical swine fever virus (CSFV) with RNase activity. Erns can induce neutralizing antibodies and provide immune protection against CSFV infection. In this study, the RNase domain of the Erns was produced in Escherichia coli. Its reactivity with CSFV-positive sera and its ability to induce antibodies and to provide protective immunity were then investigated. The serological tests showed that the prokaryotically expressed RNase domain of the Erns retained i...     

Effective Factors on Forming Precision in Patternless Casting Manufacturing Technique

The patternless casting manufacturing (PCM) technique, which adopts a new concept of double scanning method, combines the principle of discreteness and deposition with resin-bonded sand technique. This paper is to evaluate the dimensional accuracy of sand mould on PCM. The two important factors-the liquid penetration rule in the space of particles and the shape and dimension of the agglomeration unit body, which influence the process parameters such as scanning speed, layer thickness, liquid flux on dimension accuracy, and surface qualities, were investigated systematically, thus the theoretical basis for these parameters was provided. Experiments on rapid manufacturing of sand mould were carried out, and the results of the free penetration and the constraint penetration well verified the relationship of the two factors and the process parameters.     

New Voronoi Diagram Algorithm of Multiply-Connected Planar Areas in the Selective Laser Melting

This paper studies the practical generation of Voronoi diagrams for multiply-connected planar areas bounded by line segments. The core of the algorithm was calculating Voronoi polygon of every Voronoi object in planar areas independently. The main approach had two steps. The first step was calculating all relevant bisectors of every Voronoi object. The second was combining obtained bisectors into completed Voronoi polygons individually. All code was implemented in Visual C++ platform. The resulting code was extensively tested in real-world data and its practical running time grew only linearly. Three statistical CPU-consumption charts had been drawn with the Voronoi diagrams computation data, and compared with other published codes for computing Voronoi diagrams. The algorithm was applied to compute offsetting of slice area consisting of large-scale line segments for the selective laser melting (SLM) trajectory scanning technology which is a kind of rapid prototyping (RP). The experimental results of offsetting for slice area based on Voronoi diagrams show that the approach is effective and simple for polygon offsetting problems. The method is helpful to those offsetting work and can provide more effective offsetting solution.     

Rapid Manufacturing of Sand Molds by Direct Milling

Direct milling of sand molds is an important development in rapid manufacturing of sand molds. Direct milling is an effective method for manufacturing single or small batches of cast parts. This paper describes experimental investigations to find sand blocks with the appropriate strength, to describe wear patterns of different tools (high-speed steel (HSS), carbide, and polycrystalline diamond (PCD) tools), and to analyze sand mold cutting mechanisms. The results show that the PCD tool outperformes the other tools in terms of tool life. Average flank wear and micro-tipping are the dominant tool failure modes in the sand mold milling process. With a flank wear limit of 0.3 mm, the PCD tool works continuously for about 70 h under the experimental conditions. The experimental results show that the cutting mechanism for direct milling sand molds differs from metal cutting.     

Slack-nibbling battery-aware task scheduling

Dynamic voltage scaling (DVS) is an efficient approach to maximize the battery life of portable devices. A novel overall planning strategy (OPS II) balancing slack supply and demand for DVS is proposed. An OPS II-based slack-nibbling overall planning strategy (SNOPS) algorithm is also proposed, which iteratively nibbles slacks for appropriate tasks selected by an overall planning dynamic priority function to perform DVS until the slack is exhausted and an optimum voltage setting is obtained. For a high-load task set, SNOPS manages to recover battery overload while maintaining schedulability. For random variable-load task sets, SNOPS achieves a saving of 29.51% battery capacity on average, the suboptimal gap is 27.84% narrower than that of our previously proposed OPS-based algorithm, and 92.10% narrower than that of the algorithm proposed by Chowdhury et al. Results indicate that OPS II manages to save battery to various extents while maintaining schedulability, and demonstrates good load compatibility and close-to-optimal performance on average. Biography: GAO Xun(1981–), male, Ph.D. candidate, research direction: embedded system, power optimization.     

阿苯达唑自微乳的研制及稳定性分析

以阿苯达唑为模型药物,筛选其自微乳的处方并对其自微乳进行稳定性考察.通过溶解度实验、油与乳化剂的配伍实验及伪三元相图的建立,筛选阿苯达唑自微乳的组成.采用HPLC法测定处方中药物的含量并对其稳定性进行考察.阿苯达唑自微乳的组成为阿苯达唑、油酸、辛酸/葵酸三甘油酯(GTCC)、聚氧乙烯蓖麻油(Cremopher EL)和Transcutol 的质量比为0.076∶0.1∶0.1∶0.32∶0.48;强光照射(4500lx)、高温(60℃)、低温(4℃)、高低温循环实验(40℃和4℃)结果表明,该自微乳性状、含量均无明显变化.阿苯达唑自微乳能有效改善药物的溶解度,制备方法简单可行,且稳定性良好.     

位势法在交通优化问题中的应用

研究了单源多汇交通优化问题及其重要性质,提出了单源多汇交通优化问题的位势法,该算法以关于费用的最短路程为初始势,以非零流的最小费用流为初始流;用标号法找可行的增广链,在标号过程中若某点不满足平衡要求则由到达该点的可行的增广链增广最小费用流的流量;以弧割为工具,计算最小费用流的势的最大调整量,并修改最小费用流的势.算例证明了算法的正确性和复杂性及算法的有效性.     

从历史文化视角看英汉语言中的性别歧视现象

性别歧视作为一种社会现象曾普遍存在于东西方文化中.语言是文化的载体,在很大程度上是文化的一面镜子.英汉语言中带有性别歧视的词汇就是这种文化现象的反映.本文拟从历史文化视角探悉这一现象产生的根源并提出当下的应对策略.     

累进评分法在体育课田径技术教学考核中的应用

采用累进评分方程计算新标准进行田径课程的评分,并对该方法进行理论验证和实际应用的检验,证明新的评分标准能反映学生的整体水平,是一种科学、合理和实用的方法.     

同伦近似对称法：六阶Boussinesq方程的同伦级数解

提出了用以处理非线性问题的同伦近似对称法,并利用该方法研究流体动力学中的六阶Boussinesq方程.各阶相似约化解和各阶相似约化方程均可以写出通式,从而导出相应的同伦级数解.零阶相似约化方程等价于Painlevé IV型方程或Weierstrass椭圆方程,高阶相似解可以通过解线性变系数常微分方程得到.辅助参数具有调节同伦级数解的收敛性的作用.由近似对称法得到的级数解和各阶相似约化方程均能够由同伦近似对称法重新得到.