胚胎发育合子型基因激活（ZGA）的调控机制

新受精卵超越早期分裂阶段正常的发育需要胚胎基因转录的重新起动与续后调控,ZGA（合子型基因激活）是胚胎发育过程中母型调控的合子型调控过渡中的关键事件,卵为新形成合子发育程序的起动提供了特殊的环境条件,并对其调节控制起了必要的作用,各类动物早期卵裂过程的胚胎基因转录起动精确时间是可变的,涉及染色质结构成分、调控元件（顺/反式）、RNA降解、DNA复制、修饰/加工作用、卵子发生因子、合子钟及天然信号等多种因素的调节控制,本文综述了当前胚胎发育合子基因表达的时间及相关调控机制的研究进展。     

就地热再生沥青路面浅层病害影响因素分析

就地热再生技术将废旧沥青路面材料再生循环应用于道路建设和养护中,具有巨大的环保和经济效益。通过对就地热再生路面养护技术应用情况的分析,提出就地热再生路面存在的问题,并对影响就地热再生路面性能的因素进行了重点分析。     

滤波技术在实时数据处理中的应用

本文探讨了在实时数据处理中应用自适应卡尔曼滤波方法及最优预报方法。该方法具有数值稳定性好,存储量小的优点,克服了发散的缺点,具有较强的自适应性。并针对被测目标种类的多样性,测量设备的不同测量精度,以及测量设备不同的传输频率,在具体的处理中做出了相应的调整。     

A high-resolution environmental change record since 19 cal ka BP in Pumoyum Co,southern Tibet

A 380-cm-long sediment core was acquired from the deep water area of Pumoyum Co, southern Tibet. Twenty-five plant residue samples were selected, and organic carbon stable isotopes were obtained using the AMS ¹⁴C chronological method. The ¹⁴C age and carbon reservoir effect were calibrated with surface sedimentation rate measurements using ²¹⁰Pb dating. Results showed that the core sediment deposited over 19 cal ka BP. Based on a multi-proxy analysis of TOC and IC contents, grain size and pollen assemblage data, the palaeoclimatic evolution of Pumoyum Co was reconstructed since the last glacial. Pumoyum Co was a shallow lake prior to 16.2 cal ka BP; although the glacier around the lake began to melt due to increasing temperatures, climate was still cold and dry. In the interval of 16.2–11.8 cal ka BP, the sedimentary environment fluctuated drastically and frequently. Two cold-events occurred at 14.2 and 11.8 cal ka BP, and these may correspond to the Older Dryas and the Younger Dryas events, respectively. After 11.8 cal ka BP, Pumoyun Co developed into the deep lake as it is now. The lake water temperature was relatively lower at that time because of influx of cold water from glacial meltwater entering the lake. As a result, the multi-proxy indicators showed no sign of warm conditions. Comparisons between the sedimentary record of Pumoyum Co with that of other lakes of the same age in southern Tibet indicate a warmer climate following the last deglaciation influenced the southeastern Tibetan Plateau. These results imply that the southwest Asian monsoon gradually became stronger since the deglaciation during its expansion to the inner plateau. The glacial-supplied water of the lake responded sensitively to cold-events. The entire southern Tibet region was dominantly influenced climatically by the southwest Asian monsoon during the Holocene.     

Synthesis, properties, and optical applications of noble metal nanoparticle-biomolecule conjugates

Noble metal nanoparticles, such as gold or silver nanoparticles and nanorods, exhibit unique photonic, electronic and catalytic properties. Functionalization of noble metal nanoparticles with biomolecules (e.g., protein and DNA) produces systems that possess numerous applications in catalysis, delivery, therapy, imaging, sensing, constructing nanostructures and controlling the structure of biomolecules. In this paper, the recent development of noble metal nanoparticle-biomolecule conjugates is reviewed from the following three aspects: (1) synthesis of noble metal nanoparticle-biomolecule systems by electrostatic adsorption, direct chemisorption of thiol derivatives, covalent binding through bifunctional linkers and specific affinity interactions; (2) the photonic properties and bioactivation of noble metal nanoparticle-biomolecule conjugates; and (3) the optical applications of such systems in biosensors, and medical imaging, diagnosis, and therapy. The conjugation of Au and Ag nanoparticles with biomolecules and the most recent optical applications of the resulting systems have been focused on.     

具有负系数的解析函数的新子类及其性质

利用解析函数邻域的概念,并应用卷积、超几何函数构造了算子L(a,c),讨论了与算子L(a,c)相关的性质,主要证明了(n,δ)邻域以及解析函数新子类的包含关系.     

FGH95合金雾化熔滴凝固热学参数数值计算

运用等效热容法对等离子旋转电极雾化（PREP）FGH95高温合金熔滴在冷却凝固过程中的凝固热学参数进行了数值计算,给出了雾化熔滴在凝固过程中固液界面前沿的温度梯度及固液界面移动速率随固相分数的变化关系以及熔滴冷却速率和凝固时间随熔滴尺寸的变化关系。     

双S弯进气道锤激波动态特性研究

发动机喘振产生的瞬时高压引起的进气道内锤激波载荷是飞机进气道结构强度设计的关键因素之一。通过对飞行器进行内外流一体化非定常三维数值计算,分析双S弯进气道内锤激波三维流场非定常特性的演化过程,研究了不同马赫数,不同超压比对双S弯进气道锤激波载荷的影响。研究表明：锤激波经过进气道弯道时,弯道外侧流场压力远大于内侧;锤激波离开进气道入口后,进气道内流场经过数个周期逐渐恢复至初始状态;相同进气道反压时,来流马赫数越小,锤激波在进气道内部传播速度越快,且进气道内部压力系数峰值越大;相同来流马赫数下,随着超压比的增大,锤激波在进气道内部传播速度加快,进气道内部压力系数峰值增大。     

0.5—2.0eV红外光自动椭偏谱仪的研制与应用

本文介绍了一种新型的0.5～2.0eV红外光自动椭偏谱仪.采用Boxcar积分平均仪来对红外探测器输出的信号进行平均处理.大大提高了信噪比.仪器波长的变换、检偏器的步进旋转、信号的采集与处理均由微机控制.测量精度高,适用于研究材料的红外光学特性.文中给出了GaSb单晶材料红外范围光学参数的测量结果.     

离体鸡血红细胞的脆性及通透性测定

本文报道了利用7230分光光度计、显微摄影,从定性与定量上探测了多种物质溶液对鸡血红细胞的通透相对速度及导致崩解的脆性。