关于生物工程技术与水污染控制的思考

文章概括介绍生物工程技术的概念、特点、发展状况以及在废气处理和固体废物处理中的应用,重点介绍生物工程技术在污水处理中的应用。     

基于混合DBN的海上编队通信链路威胁估计

针对海上编队通信链路威胁估计涉及因素多、知识表示与推理存在不确定性等问题,分析了海上编队通信链路威胁要素,依据要素间因果关系建立了通信链路威胁估计的混合动态贝叶斯网络(DBN)模型,提出了混合DBN模型中连续型网络节点变量的学习方法。仿真分析证实了该方法的有效性和可操作性。     

A second generation human haplotype map of over 3.1 million SNPs

We describe the Phase II HapMap, which characterizes over 3.1 million human single nucleotide polymorphisms (SNPs) genotyped in 270 individuals from four geographically diverse populations and includes 25-35% of common SNP variation in the populations surveyed. The map is estimated to capture untyped common variation with an average maximum r2 of between 0.9 and 0.96 depending on population. We demonstrate that the current generation of commercial genome-wide genotyping products captures common Phase II SNPs with an average maximum r2 of up to 0.8 in African and up to 0.95 in non-African populations, and that potential gains in power in association studies can be obtained through imputation. These data also reveal novel aspects of the structure of linkage disequilibrium. We show that 10-30% of pairs of individuals within a population share at least one region of extended genetic identity arising from recent ancestry and that up to 1% of all common variants are untaggable, primarily because they lie within recombination hotspots. We show that recombination rates vary systematically around genes and between genes of different function. Finally, we demonstrate increased differentiation at non-synonymous, compared to synonymous, SNPs, resulting from systematic differences in the strength or efficacy of natural selection between populations.     

Genome-wide detection and characterization of positive selection in human populations

With the advent of dense maps of human genetic variation, it is now possible to detect positive natural selection across the human genome. Here we report an analysis of over 3 million polymorphisms from the International HapMap Project Phase 2 (HapMap2). We used 'long-range haplotype' methods, which were developed to identify alleles segregating in a population that have undergone recent selection, and we also developed new methods that are based on cross-population comparisons to discover alleles that have swept to near-fixation within a population. The analysis reveals more than 300 strong candidate regions. Focusing on the strongest 22 regions, we develop a heuristic for scrutinizing these regions to identify candidate targets of selection. In a complementary analysis, we identify 26 non-synonymous, coding, single nucleotide polymorphisms showing regional evidence of positive selection. Examination of these candidates highlights three cases in which two genes in a common biological process have apparently undergone positive selection in the same population:LARGE and DMD, both related to infection by the Lassa virus, in West Africa;SLC24A5 and SLC45A2, both involved in skin pigmentation, in Europe; and EDAR and EDA2R, both involved in development of hair follicles, in Asia.     

Tibetan plateau aridification linked to global cooling at the Eocene-Oligocene transition

Continental aridification and the intensification of the monsoons in Asia are generally attributed to uplift of the Tibetan plateau and to the land-sea redistributions associated with the continental collision of India and Asia, whereas some studies suggest that past changes in Asian environments are mainly governed by global climate. The most dramatic climate event since the onset of the collision of India and Asia is the Eocene-Oligocene transition, an abrupt cooling step associated with the onset of glaciation in Antarctica 34 million years ago. However, the influence of this global event on Asian environments is poorly understood. Here we use magnetostratigraphy and cyclostratigraphy to show that aridification, which is indicated by the disappearance of playa lake deposits in the northeastern Tibetan plateau, occurred precisely at the time of the Eocene-Oligocene transition. Our findings suggest that this global transition is linked to significant aridification and cooling in continental Asia recorded by palaeontological and palaeoenvironmental changes, and thus support the idea that global cooling is associated with the Eocene-Oligocene transition. We show that, with sufficient age control on the sedimentary records, global climate can be distinguished from tectonism and recognized as a major contributor to continental Asian environments.     

滩涂湿地利用与保护的协调发展探讨 ———以上海市为例

文章就潮滩一词探索其定义,明确其研究范围,以长江口———上海市潮滩、湿地为例,论述其基本     

促进山西转型发展的研究

随着经济全球化进程的加快,中国经济发展的战略重点已开始由沿海地区向中部地区转移,给山西发展带来了大好机遇.文章从山西的优势、瓶颈问题及解决对策等方面进行了阐述,必将对山西转型发展起到一定的借鉴作用.     

Micro-expression recognition algorithm based on the combination of spatial and temporal domains

Aiming at the problem of unsatisfactory effects of traditional micro-expression recognition algorithms,an efficient micro-expression recognition algorithm is proposed,which uses convolutional neural networks(CNN) to extract spatial features of micro-expressions,and long short-term memory network(LSTM) to extract time domain features.CNN and LSTM are combined as the basis of micro-expression recognition.In many CNN structures,the visual geometry group(VGG) using a small convolution kernel is finally selected as the pre-network through comparison.Due to the difficulty of deep learning training and over-fitting,the dropout method and batch normalization method are used to solve the problem in the VGG network.Two data sets CASME and CASME II are used for test comparison,in order to solve the problem of insufficient data sets,randomly determine the starting frame,and a fixedlength frame sequence is used as the standard,and repeatedly read all sample frames of the entire data set to achieve trayersal and data amplification.Finallv.a hieh recognition rate of 67.48% is achieved.     

σ-π共轭高分子导电性的理论研究

采用密度泛函(DFT)和PBC方法对σ-π共轭高分子电子结构和带隙进行理论研究,电荷掺杂和聚合物中π共轭链长度对带隙降低起到重要作用,发现PBD是一种窄带隙的高分子.     

基于MVA的半导体生产过程质量分析方法

针对半导体晶圆生产中存在着位置间变异、晶圆间变异及批次间变异,提出了基于多变异分析(MVA)的工序质量分析方法.该方法通过建立基于方差分析晶圆生产工序质量的多变异分析模型,研究了晶圆生产过程中3种变异与总变异之间的定量关系.由定量关系推导出晶圆生产中的抽样规则,并提出了3种常用过程能力指数Cp,Cpk和Cpm的改进计算方法.通过在晶圆生产中的实际应用,证明了该方法中的抽样规则能捕获加工过程中主要随机变异,该方法计算获得的过程能力指数可较为真实地反映生产过程质量状况.