某高速公路大修养护方案设计

随着我国经济的快速发展、交通量的迅猛增长,已运营公路的养护大修工程也付诸实施。就某高速公路养护大修改造工程的实施,提出养护大修综合处治方案设计时的一些方案比选。     

肝癌介入治疗现状

为探讨肝癌目前的治疗现状,综合国内外近10 a来已公开发表的论著、文献阐述肝癌介入治疗的现状,归纳总结文献中关于肝癌介入治疗的不同方法,比较各自的优劣.认为肝癌介入治疗方法较多,目前缺乏规范,主张综合治疗为主,实施个体化方案.     

黄土公路隧道预支护施工技术研究

针对目前黄土公路隧道设计与施工的现状以及存在的问题,结合在建古浪隧道实体工程,分析了小导管注浆超前支护施工技术的要点,利用ANSYS程序建立三维实体模型分析预支护技术对开挖围岩的稳定性影响及围岩和支护结构在施工过程中的受力变化情况.结果表明,超前支护可以提高围岩自稳自承的能力,减小围岩的收敛变形.     

A tension-induced mechanotransduction pathway promotes epithelial morphogenesis

Mechanotransduction refers to the transformation of physical forces into chemical signals. It generally involves stretch-sensitive channels or conformational change of cytoskeleton-associated proteins. Mechanotransduction is crucial for the physiology of several organs and for cell migration. The extent to which mechanical inputs contribute to development, and how they do this, remains poorly defined. Here we show that a mechanotransduction pathway operates between the body-wall muscles of Caenorhabditis elegans and the epidermis. This pathway involves, in addition to a Rac GTPase, three signalling proteins found at the hemidesmosome: p21-activated kinase (PAK-1), the adaptor GIT-1 and its partner PIX-1. The phosphorylation of intermediate filaments is one output of this pathway. Tension exerted by adjacent muscles or externally exerted mechanical pressure maintains GIT-1 at hemidesmosomes and stimulates PAK-1 activity through PIX-1 and Rac. This pathway promotes the maturation of a hemidesmosome into a junction that can resist mechanical stress and contributes to coordinating the morphogenesis of epidermal and muscle tissues. Our findings suggest that the C. elegans hemidesmosome is not only an attachment structure, but also a mechanosensor that responds to tension by triggering signalling processes. We suggest that similar pathways could promote epithelial morphogenesis or wound healing in other organisms in which epithelial cells adhere to tension-generating contractile cells.     

基于KULLBACK信息融合方法的系统可靠性评估

在产品具有多源验前信息的情形下,讨论冷贮备系统的可靠性评估问题,运用Kullback信息作为分布之间距离的度量,在Kullback信息的融合准则下对多个先验分布进行融合。并以融合后的先验分布作为产品的最终验前分布,对冷贮备系统的可靠性指标进行Bayes估计。最后进行的计算机随机模拟结果表明,文中所提出的方法合理且便于应用。     

核技术与纳米技术

Nuclear science and technology(NST,here after)are based on nuclear properties,nuclear structures,nuclear effects,nuclear reactions,and nuclear radiations that highly rely on nuclear spectroscopy and nuclearfacilities,like nuclear reactors and accelerators…     

寒地城市突发公共卫生事件应对的规划响应

在全球气候变化的背景下,特殊的气候条件引发的城市突发公共卫生事件不容忽视.城市规划是政府确保公共卫生安全的重要手段,从城市规划角度预防及控制气候变化带来的突发公共卫生事件并作出一定的规划响应,对于提升寒地城市居民健康水平具有重要意义.以寒地城市为例,分析了地域气候特征对突发公共卫生事件的影响,结合城乡人口空间分布、土地...     

基于进度优化的大型项目激励机制模型

在项目管理实践中,业主通常会设立激励机制以确保项目按期完成,而承包商则会根据业主设定的激励机制合理安排项目进度.本文讨论了大型项目的激励机制,研究了业主和承包商的决策问题,建立了以项目收益净现值最大化为目标函数的Stackelberg主从递阶决策模型.通过各子项目激励强度的设定对激励机制进行优化,协调业主和各承包商的利益关系,进而实现业主收益的最大化.     

数字图像处理技术对影响投篮命中相关因素的分析

以基础力学理论对篮球飞行轨迹进行运算和分析,近年来专业体育科研机构也开始利用该方法对体育运动项目进行辅助分析。文章利用数字图像处理的基本技术,对影响篮球投篮命中率的相关因素进行研究,实验结果表明对提高运动技术水平具有一定的参考意义。     

Mechanism Construction of Human Resource Management based on Blockchain Technology

The traditional human resource management system is faced with such problems as the quality of staff recruitment can not be guaranteed, the training performance is not consistent with the actual performance, the enterprise performance appraisal is unfair, and the salary distribution is unfair, which seriously affects the enthusiasm and loyalty of employees and threatens the survival and development of enterprises. In view of the current situation and problems of human resource management system, combined with the technical characteristics of blockchain, this paper proposes a human resource management mechanism based on blockchain technology, in order to achieve the company's human resource management system accurate, efficient, open and transparent. It is found that there is a good coupling between blockchain technology and human resource management system. This paper constructs a human resource management mechanism based on blockchain, innovates the application scenarios of blockchain technology, and provides certain guiding significance for the establishment of human resource management system and process improvement in the future.